جست‌وجوی استاد و پژوهشگر

Jennifer Rossمشاهده پروفایل

استاد

• Biophysics
• Soft Matter Physics
• Biological Condensed Matter Physics
• +۵ مورد دیگر

Jennifer Ross is a Professor of Physics and Associate Dean for Creativity, Scholarship, and Research at the College of Arts & Sciences of Syracuse University . As a biophysicist, she investigates how cells organize their interiors through self-assembly and active matter principles, focusing on the microtubule cytoskeleton and enzyme-driven systems using single-molecule imaging . Her research bridges fundamental physics with biological organization . Education: Ph.D. in Physics, University of California, Santa Barbara (2004) B.A. in Physics and Mathematics, Wellesley College (2000) Research Focus: Self-organization of cytoskeletal networks Active matter dynamics in biological systems Motor protein interactions and cargo transport Programming circadian materials via biomolecular systems Microtubule severing mechanisms Recent Article Trends: 2025 studies explore kinesin-driven cytoskeletal composites, urease-DNA origami engineering, and crosslinker-regulated network mechanics 2024-2023 work examines ionic strength effects on microtubules, programmable circadian materials, and motor-cargo dynamics Earlier studies analyze actin-microtubule composites, liquid crystal phase control, and severing enzyme mechanisms Scientific Awards: Fellow of the American Physical Society (APS) and American Association for the Advancement of Science (AAAS) Cottrell Scholar (2025) and STAR Award Margaret Oakley Dayhoff Award (Biophysical Society) Grants: Leads multiple NSF, Sloan Foundation, and Research Corporation grants for projects like "Energy and Entropy Sculpting" and "Explorations: SUPER-Tech SHIP" . Teaching: Offers courses in experimental physics, microscopy, and biophysics, including a globally adopted hands-on microscope-building curriculum. Lab: Heads the Bio-Active Matter Lab , studying how cells harness noisy systems for autonomous organization.

Joseph A. Novemberمشاهده پروفایل

دانشیار

• History of Science and Technology
• Biomedical Computing
• History of Medicine
• +۳ مورد دیگر

Joseph A. November is an Associate Professor in the Department of History at the University of South Carolina, affiliated with the McCausland College of Arts and Sciences. His research focuses on the history of biomedical computing, distributed computing, and the intersection of technology and medicine. He holds a Ph.D. from Princeton University (2006), an M.A. from the University of Chicago (2002), and a B.A. from Hamilton College (1997). His work includes the award-winning book Biomedical Computing: Digitizing Life in the United States (2012), which explores the co-development of biomedicine and computing technologies. Current projects include Revolutions@home , examining distributed computing in protein folding research, and a biography of computing pioneer Robert S. Ledley. He has received grants from the NSF, NIH, and the Charles Babbage Institute. Teaching interests span the history of science and technology, including courses on the history of medicine, digital humanities, and the role of games in historical education. He actively contributes to professional organizations like SHOT and the History of Science Society. Awards include the Computer History Museum Prize (2013) and the National Institutes of Health DeWitt Stetten Fellowship (2007-2008). His research bridges historical analysis with contemporary issues in technology and biomedical ethics.

Omar A. Salehمشاهده پروفایل

استاد

• Biophysics
• Soft Matter Physics
• Polymer Physics
• +۵ مورد دیگر

Professor Omar A. Saleh is a distinguished physicist and materials scientist at the University of California, Santa Barbara, holding appointments in both the Materials and Physics Departments. Since summer 2023, he has served as Chair of the Materials Department and maintains a minority appointment in the Biomolecular Science and Engineering (BMSE) Program, where he previously served as Director from 2013-2017. His educational background includes a B.S. in Physics from MIT (1997) and a Ph.D. in Physics from Princeton (2003), supported by a Hertz Fellowship. Following postdoctoral work at École Normale Supérieure in Paris developing single-molecule techniques for motor protein/DNA studies, he joined UCSB in 2005. Saleh's research centers on fundamental principles of biomolecular behavior through experimental investigation of biopolymer elasticity and biomimetic organelles. His lab pioneers precision single-molecule stretching experiments to study entropic/energetic contributions in soft systems and creates life-like behaviors using reconstituted nucleic acid/protein assemblies. Key focus areas include DNA nanostar phase separation, liquid-liquid phase behavior, intrinsically disordered proteins, and non-equilibrium biomolecular systems. His publication trends reveal a strong emphasis on biomolecular condensates (2023-2025), with recurring themes in DNA nanotechnology, polyelectrolyte physics, and single-molecule mechanics. Recent work explores tension-mediated control of phase separation, transcriptional regulation of biomolecular liquids, and active matter principles in DNA systems. NSF CAREER Award (2008) Bessel Research Award from Alexander von Humboldt Society (2017) Fellow of the American Physical Society (2019) Saleh actively mentors graduate students and postdocs including Sam Wilken, Gabrielle Abraham, Anna Nguyen, and Aria Chaderjian, whose research spans DNA nanostar liquids, active droplets, and complex coacervation. His lab develops innovative instrumentation including high-speed magnetic tweezers and GPU-based tracking systems, supported by grants such as NSF/MCB-BSF: Direct force measurements of intrinsically disordered proteins. The Saleh Group operates at BioE 3006, focusing on creating quantitative models of biological function through physical reconstitution.

• Epigenetics
• Retroelements
• Transposable elements
• +۵ مورد دیگر

Didier Trono is a Full Professor at École Polytechnique Fédérale de Lausanne (EPFL), where he leads the Laboratory of Virology and Genetics (LVG) within the School of Life Sciences. Formerly, from 2004 to 2012, he served as the founding dean of EPFL's Faculty of Life Sciences, orchestrating its development and growth during this formative period. Trono received his medical education at the University of Geneva, followed by clinical training in pathology, internal medicine, and infectious diseases in Geneva and at Massachusetts General Hospital in Boston. His scientific career began at the Whitehead Institute of MIT, and in 1990 he was recruited by the Salk Institute of San Diego to launch an AIDS research center. After seven years in the United States, he returned to Europe and eventually joined EPFL. Dr. Trono's research has evolved significantly over his career. Initially focusing on virus-host interactions, he studied pathogens like HIV and Hepatitis B virus, creating HIV-derived genetic transfer tools that are now successfully used in gene therapy. For approximately the last fifteen years, his research has centered on epigenetics, particularly exploring the impact of retroelements and their control mechanisms on development and physiology of higher organisms, including humans. His laboratory investigates how transposable elements and KRAB zinc finger proteins regulate gene expression, with important implications for understanding cancer biology and developing new diagnostic and therapeutic approaches. Analysis of his recent publications (2022-2024) reveals a strong focus on transposable elements, KRAB zinc finger proteins, and their roles in gene regulation and cancer. His work combines molecular biology, genomics, and bioinformatics approaches to understand how these ancient viral remnants have been co-opted by the host genome to regulate development and cellular functions. The research spans basic molecular mechanisms to potential clinical applications in cancer diagnosis and therapy, with some recent work also addressing SARS-CoV-2 and immune responses. Throughout his career, Professor Trono has mentored numerous PhD students, including Bojkowska Karolina, Brandão Sanches Vong Martins Filipe Amândio, Bulliard Yannick, Coluccio Andrea, Corsinotti Andrea, Coudray Alexandre, De Tribolet-Hardy Jonas Caspar, and Dorschel Iris Arianna. His laboratory has received significant funding to support research at the intersection of virology, genetics, and epigenetics, contributing to EPFL's reputation as a leading institution in life sciences research. The Trono Laboratory continues to be at the forefront of research on retroelements and their regulatory mechanisms, maintaining a vibrant research environment that bridges fundamental biological questions with potential medical applications, particularly in cancer research and precision medicine.

Tommi Jaakkolaمشاهده پروفایل

استاد

• Machine Learning
• Artificial Intelligence
• Computational Biology
• +۷ مورد دیگر

Tommi Jaakkola is the Thomas Siebel Professor of Electrical Engineering and Computer Science and the Institute for Data, Systems, and Society at the Massachusetts Institute of Technology. He received his MSc in theoretical physics from Helsinki University of Technology in 1992 and his PhD from MIT in computational neuroscience in 1997. After completing a postdoctoral position in computational molecular biology as a DOE/Sloan fellow at UCSC, he joined the MIT EECS faculty in 1998. His research advances how machines can learn, predict or control, and do so at scale in an efficient, principled, and interpretable manner. His work in machine learning extends from foundational theory to modern applications, focusing especially on statistical inference and estimation tasks that lie at the heart of complex learning problems. He designs new methods, theory and algorithms to automate the use and generation of semi-structured data such as natural language text, images, molecules, or strategies. Jaakkola applies and develops algorithms to solve multi-faceted recommender, retrieval, or inferential tasks (particularly in biomedical contexts), design and optimize molecules or reactions for drug design, and model strategic, game theoretic interactions. His recent work heavily focuses on diffusion models, protein structure prediction, molecular design, and generative AI, with significant publications in top conferences including ICML, NeurIPS, and ICLR. His scientific contributions span multiple disciplines with significant impact in both theoretical machine learning and practical applications in computational biology and chemistry, including notable work on antibiotic discovery published in Cell. Current advisees: Julia Balla, Bowen Jing, Hannes Stärk, Peter Holderrieth, Chenyu Wang Recent graduates: Gabriele Corso (Boltz PBC), Ezra Erives (DE Shaw), Jason Yim (Xaira) Jaakkola maintains an active research program through MIT's Computer Science and Artificial Intelligence Laboratory (CSAIL) and the Institute for Data, Systems, and Society (IDSS), with his office located in the Stata Center (32-G470). His work bridges theoretical machine learning with practical applications, making significant contributions to both the academic field and potential real-world impact in healthcare and drug discovery.

Harris H. Wangمشاهده پروفایل

دانشیار

• Systems Biology
• Synthetic Biology
• Genome Engineering
• +۱۷ مورد دیگر

Harris H. Wang is an Associate Professor in the Department of Systems Biology and Department of Pathology and Cell Biology at Columbia University's Vagelos College of Physicians and Surgeons, where he also serves as Interim Chair of Systems Biology. He is affiliated with the Center for Computational Biology and Bioinformatics (C2B2) and the Integrated Program in Cellular, Molecular and Biomedical Studies (CMBS). B.S., Physics and Mathematics, MIT Ph.D., Biophysics, Harvard University Dr. Wang's research lies at the intersection of systems and synthetic biology, focusing on developing foundational technologies for genome engineering, microbiome manipulation, and synthetic genomics. His lab pioneers methods such as MAGE, MAGIC, CAST, and CAMII to enable high-throughput genetic manipulation, in situ microbiome engineering, and AI-driven microbial culturomics. Key research themes include understanding microbial community dynamics, engineering cellular memory systems, designing biocontained genetic circuits, and applying synthetic biology to human health challenges in personalized medicine and infectious disease. His recent publications reveal a strong trend in spatial and functional metagenomics, CRISPR-based microbiome editing, and synthetic biology tools for data storage and genetic stability. The articles span high-impact journals like Nature , Science , and Nature Biotechnology , reflecting his leadership in developing scalable, programmable biological systems. Scientific Awards: NIH Director’s Early Independence Award Forbes 30 Under 30 in Science Sloan Research Fellowship NSF CAREER Award ONR Young Investigator Award Burroughs Wellcome Fund PATH Award Schaefer Scholar Blavatnik National Award Vilcek Prize PECASE Dr. Wang has advised numerous PhD and postdoctoral researchers, many of whom have gone on to independent scientific careers. His lab is supported by major grants from NIH, NSF, DARPA, DOE, and foundations including the Bill & Melinda Gates Foundation and CZ Biohub NY. He is actively involved in educational initiatives, including organizing Columbia’s iGEM team and the Cold Spring Harbor Laboratory Synthetic Biology course. The Wang Lab is based at the Columbia University Irving Medical Center and is part of national consortia such as the Engineering Biology Research Consortium (EBRC) and the Genome Project-Write (GP-Write) initiative. The lab develops and applies cutting-edge technologies in automation, machine learning, and synthetic biology to engineer microbiomes for applications in medicine, global health, and climate change.

Keith Alexander Sharkeyمشاهده پروفایل

استاد

• Enteric nervous system
• Gut-brain axis
• Endocannabinoid system
• +۳ مورد دیگر

Dr. Keith Alexander Sharkey is a Professor in the Department of Physiology and Pharmacology at the Cumming School of Medicine, University of Calgary. He is also a Full Member of both the Hotchkiss Brain Institute and The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases. Dr. Sharkey has been at the University of Calgary since his appointment as Assistant Professor in 1990, dedicating his career to understanding the neural control of the gastrointestinal tract. From 2005-2021, he held the Crohn's and Colitis Canada Chair in Inflammatory Bowel Disease Research, demonstrating his longstanding commitment to advancing knowledge in gastrointestinal sciences. Dr. Sharkey's educational journey began with a BSc (Hons) in Nutrition from the University of London in 1981, followed by a PhD in Physiology from the University of Liverpool in 1985. After completing postdoctoral training in Hungary, the UK, and Canada, he joined the University of Calgary faculty in 1990, where he has remained throughout his distinguished academic career. Dr. Sharkey's research program centers on understanding the physiology and pathophysiology of the neural control of the gastrointestinal tract and brain-gut interactions in health and disease. His laboratory investigates two main areas: the role of the endocannabinoid system in regulating GI motility and intestinal barrier function, and the physiology of the enteric nervous system in controlling motility and barrier function. His work employs state-of-the-art approaches including live cell imaging and molecular genetics. Recent publications show his expanding interest in connections between gut function and neurodegenerative conditions like ALS, with multiple 2024-2025 papers examining sexual dimorphism in disease processes and gut-brain axis mechanisms. Fellow, Royal Society of Canada (2024) Cumming School of Medicine's van de Sande Distinguished Achievement Award for Mentorship (2021) Distinguished Research Award, American Physiological Society (2021) Finkelstein Award for Excellence, Crohn's and Colitis Canada (2016) Fellow, Canadian Academy of Health Sciences (2015) Fellow, Canadian Association of Gastroenterology (2015) Killam Annual Professor Award, University of Calgary (2013) Dr. Sharkey has mentored numerous students throughout his career, as evidenced by his 2021 Mentorship Award. His research is supported by significant funding, including a CIHR Foundation grant exploring how enteric nerves and glia maintain intestinal homeostasis. He has also participated in university strategic initiatives focused on Brain and Mental Health (2015-2021) and Infections, Inflammations and Chronic Diseases (2015-2021), demonstrating his interdisciplinary approach. The Sharkey Lab provides a safe, inclusive, and diverse research environment that encourages open scientific exchange from diverse viewpoints. His laboratory is actively engaged in multiple collaborative projects, including investigations with UBC Okanagan on diet and probiotics targeting the gut-brain metabolic interactome, and with University of Calgary colleagues studying gut microbiota's role in ALS. Dr. Sharkey continues to advance our understanding of neural mechanisms controlling gastrointestinal function with upcoming courses scheduled for Fall 2024 and Winter 2025.

Thomas Walzمشاهده پروفایل

استاد

• Membrane Biology
• Structural Biology
• Cryo-electron Microscopy
• +۵ مورد دیگر

Thomas Walz, PhD, is a Professor at The Rockefeller University and Head of the Laboratory of Molecular Electron Microscopy. Previously, he held positions as Assistant, Associate, and Professor at Harvard Medical School (1999–2015) and was an Investigator at the Howard Hughes Medical Institute (2008–2015). He earned his PhD and BS in biophysics from the University of Basel, Switzerland, and completed postdoctoral research at the University of Sheffield. Walz completed his education at the Biozentrum, University of Basel, Switzerland, where he received his Diploma in Biophysics (1992) and PhD in Biophysics (1996). He furthered his training as a postdoctoral researcher at the University of Sheffield (1996–1999). His research focuses on understanding membrane-related processes and the structural biology of membrane proteins in lipid environments. Utilizing cryo-electron microscopy and nanodisc technology, he investigates how lipid bilayers influence membrane protein structure and function. Key areas include mechanosensitive channels, T-cell receptor dynamics, and telomere maintenance mechanisms. Collaborations with the de Lange lab explore the CST-Polα/primase complex's role in telomere regulation. Walz has been recognized with the Genzyme Award for Outstanding Achievement in Biomedical Sciences (2004) and continues to contribute to advancements in structural biology and membrane protein research. While specific student advisees are not listed, Walz actively mentors through his roles in the David Rockefeller Graduate Program and Tri-Institutional programs. His research is supported by grants and institutional funding, though specific grants are not detailed here. He directs the Laboratory of Molecular Electron Microscopy at Rockefeller, a hub for innovative structural biology and membrane protein studies. The lab collaborates widely, integrating cryo-EM with electrophysiology and molecular dynamics simulations.

• Plant Biotechnology
• Molecular Biology
• Synthetic Biology
• +۵ مورد دیگر

Jun Hyung Lee is a Visiting Assistant Professor in the Department of Environmental Biology at SUNY College of Environmental Science and Forestry (ESF). His research focuses on advancing forest tree improvement and conservation through molecular and synthetic biology approaches, with a particular emphasis on enhancing plant resilience to environmental stresses via beneficial microbial interactions. He teaches courses in plant biotechnology and tissue culture methods. Education includes a Ph.D. in Forest Genetics from Purdue University (USA), and M.S. and B.S. degrees in Plant Science from Seoul National University (South Korea). His work integrates cutting-edge genetic engineering techniques with ecological studies to address challenges in plant stress tolerance, symbiosis, and epigenetic regulation. Recent projects include identifying novel symbiosis pathways for thermotolerance and analyzing flooding tolerance in hybrid poplars. Publications highlight contributions to plant-microbe interaction research, synthetic biology applications, and genome editing epigenetic impacts. Collaborations span institutions like Oak Ridge National Laboratory and the University of Georgia, reflecting his transdisciplinary approach to plant science. Lee’s teaching emphasizes practical skills in biotechnology, bridging laboratory innovation with field applications.

Sriram Subramaniamمشاهده پروفایل

استاد

• cryo-electron microscopy
• structural biology
• drug-design
• +۴ مورد دیگر

Sriram Subramaniam is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia (UBC) and holds the Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design. His research leverages cryo-electron microscopy (cryo-EM) to advance structural biology and drug design, focusing on protein dynamics and therapeutic target identification. Education: PhD in Physical Chemistry (1987) from Stanford University; MSc in Chemistry (1981) from Indian Institute of Technology, Kanpur. Subramaniam's interdisciplinary work combines cryo-EM with computational tools and molecular biology to study protein structures at atomic resolution. His lab has pioneered cryo-EM applications in precision medicine, including mapping small molecule drugs on patient-specific cancer mutants. Recent publications (2024-2022) highlight his contributions to understanding SARS-CoV-2 immune evasion, structural mechanisms of ATPases, and AI integration in structural biology. His research spans viral entry mechanisms, CRISPR systems, and neurodegenerative disease pathways. Scientific Awards: Gobind Khorana Canada Excellence Research Chair NIH Director’s Award for Scientific Excellence Fellow of the Biophysical Society Breakthrough Prize nomination Based at the Djavad Mowafaghian Center for Brain Health, Subramaniam leads the Program in Cryo-EM Guided Drug Design, contributing to over 177 peer-reviewed publications with a career h-index of 58 and citations exceeding 12,340.

Adam Runionsمشاهده پروفایل

پژوهشگر

• Computational Modeling
• Developmental Biology
• Computer Science
• +۴ مورد دیگر

Adam Runions is a researcher in the Department of Computer Science at the University of Calgary, leading the MPG Partner Group in computational analysis of leaf development through collaborative work with Miltos Tsiantis. His group is embedded in the Graphics Cluster, focusing on interdisciplinary problems at the intersection of computer science and developmental biology. University of Calgary - Department of Computer Science MPG Partner Group (2022) Graphics Cluster affiliation His research explores computational modeling and analysis of plant form and development across multiple scales, integrating geometric modeling, physically-based simulation, and computer-aided design. Key themes include plant morphogenesis, self-organization of natural forms, and cross-disciplinary applications in computer graphics and animation. Recent publications emphasize plant development (leaf shape, bark patterning), mathematical modeling (auxin-driven patterning), and geometric techniques (subdivision surfaces, PUPs). Collaborations span institutions like the Max Planck Institute for Plant Breeding Research. Scientific Awards Marie Sklodowska-Curie Fellowship Best Paper Award (International Conference on Cyberworlds 2015) Best Student Paper Award (Computer Graphics International 2011) The group actively recruits BSc, MSc, and PhD students with backgrounds in computer science and mathematics for projects on plant form simulation and digital content creation. Research integrates evolutionary biology, biomechanical modeling, and computational techniques.

Syed Hani Hassan Abidiمشاهده پروفایل

دانشیار

• Virology
• Immunology
• Viral Oncology
• +۷ مورد دیگر

Syed Hani Hassan Abidi is an Associate Professor at the Department of Biomedical Sciences , School of Medicine , Nazarbayev University , Kazakhstan. His research integrates virology , immunology , viral oncology , and bioinformatics , with a focus on HIV molecular epidemiology , viral evolution , and drug resistance . He has led international projects across Pakistan, Kenya, Afghanistan, and Kazakhstan, and is recognized for innovative teaching and MOOC development. Education: PhD in Virology and Immunology Research Interests: His laboratory employs bioinformatics (machine learning, AI), genomics , and proteomics to study HIV phylodynamics , viral co-infections , and oncogenic viruses like EBV in prostate cancer. He also explores microbiome-immunity interactions and designs antiviral drugs/vaccines . Recent Research Trends: His 2025 publications emphasize COVID-19 immunopathology , HIV/syphilis epidemiology in Pakistan , and particle physics contributions via ATLAS , showcasing interdisciplinary impact. Awards & Recognition: Outstanding Teachers Award (2019, Aga Khan University) Fellowship of Higher Education (UK, 2022) Teaching & Grants: He pioneered Pakistan’s first MOOC on Computer-Based Drug Discovery (2014) and received a 2022 SoTL grant for MOOC-based molecular biology education. His teaching integrates animations , films , and flipped classrooms . Collaborations & Labs: Leads projects on HIV drug resistance , HCV genomics in Kazakhstan , and AI-driven dementia diagnostics (Kazakh Brain Atlas). His lab collaborates with global institutions to advance viral disease surveillance and therapeutic innovation .

Jiaxuan Youمشاهده پروفایل

استادیار

• Graph Neural Networks
• Relational Data
• Machine Learning Systems
• +۹ مورد دیگر

Jiaxuan You is an Assistant Professor at the Siebel School of Computing and Data Science, University of Illinois at Urbana-Champaign, leading the U Lab focused on achieving Artificial General Intelligence (AGI) in digital environments. His research spans graph neural networks (GNNs), relational data, foundation models, and machine learning systems. PhD and MS in Computer Science from Stanford University (2021) Developed GraphGym and PyTorch Geometric (PyG) for graph learning Core member at Kumo AI (2021-2023) His research explores: Graph-enhanced LLMs: Integrating relational structures into foundation models AGI Development: Self-optimizing AI agents and tool utilization ML Systems: Scalable architectures and redundancy-free computation Interdisciplinary Applications: Financial networks, crop yield prediction, and metro systems Recent publications focus on temporal reasoning, multi-agent dynamics, and hybrid architectures for LLMs. He actively develops open-source tools like DBGYM and GraphRouter. Scientific recognition includes: JPMC PhD Fellowship Baidu Scholarship Best Student Paper at AAAI 2017 World Bank Big Data Innovation Challenge winner He mentors PhD and intern students, emphasizing machine learning systems expertise. His lab collaborates on AGI workshops (e.g., ICLR 2024) and industry projects.

Daniel Finleyمشاهده پروفایل

استاد

• Ubiquitin-Proteasome Pathway
• Proteostasis
• Protein Degradation
• +۷ مورد دیگر

Daniel Finley is a Professor of Cell Biology at Harvard Medical School (HMS), leading the Finley Lab focused on the ubiquitin-proteasome pathway and related regulatory mechanisms. He holds academic appointments within the Department of Cell Biology and sits on the Scientific Advisory Boards of Proteostasis and X-Chem Pharmaceuticals. His research investigates proteasome function, ubiquitin-like proteins, and proteostasis roles in diseases like Alzheimer’s and ALS. Dr. Finley earned his undergraduate degree in biochemistry from Harvard University and a Ph.D. in molecular biology from MIT. After postdoctoral training at MIT, he joined HMS in 1988. His lab explores topics including erythroid proteome remodeling, mitochondrial dysfunction, and neurodegenerative disease mechanisms. Key research areas include: (1) Ubiquitin-proteasome pathway regulation, (2) Proteasome structure/function, (3) Nonproteolytic roles of ubiquitination, and (4) Pathophysiological roles of proteostasis defects in diseases. His work bridges basic cell biology with translational medicine, particularly in neurodegeneration and anemia. Finley has secured NIH funding for projects like 'Regulation of Proteasome Activity' (R35GM145246) and 'Erythrocyte maturation through global proteome remodeling' (R01HL153970). Collaborations with industry and academic partners extend his impact in drug discovery and proteasome-targeted therapies. His lab’s contributions include defining ubiquitin chain editing mechanisms, identifying USP14’s role in mitophagy, and elucidating proteostasis defects in Alzheimer's models. Research tools developed include advanced cryo-EM analyses of proteasomal structures and functional assays for ubiquitin system enzymes.

Björn Corziliusمشاهده پروفایل

استاد

• Solid-state NMR Spectroscopy
• Dynamic Nuclear Polarization (DNP)
• Biomolecular Chemistry
• +۳ مورد دیگر

Prof. Dr. Björn Corzilius is a University Professor (W2) of Physical Chemistry at the University of Rostock, Germany, leading the Corzilius group. His research focuses on solid-state NMR spectroscopy, dynamic nuclear polarization (DNP), and applications in biomolecules and materials. He holds affiliations with the Leibniz Institute for Catalysis (LIKAT) and serves on multiple academic boards, including the transregional Collaborative Research Center TRR 386 and the journal Magnetic Resonance . Education: 1999: Studies of Chemistry, TU Darmstadt 2005: Diploma in Physical Chemistry (TU Darmstadt) 2008: Ph.D. in Physical Chemistry (TU Darmstadt) Research Interests: Solid-state NMR, DNP for sensitivity enhancement, paramagnetic metal ions, biomolecular dynamics, and method development. His work bridges theoretical and experimental approaches to advance structural and functional studies of complex systems like proteins, nucleic acids, and catalytic materials. Recent Article Trends: Focus on DNP applications in biomolecular interfaces, novel polarizing agents (e.g., Gd(III) complexes), and methodological advancements like serial polarization transfer and electron-decoupled DNP. Contributions span inorganic chemistry, materials science, and biophysical systems. Awards: Emmy Noether Fellowship (2012) Felix Bloch Lecture (2016) Regitze M. Vold Memorial Prize (2017) Best Ph.D. Supervision (2018) Grants & Labs: Principal Investigator of the Emmy Noether Group (2013–2019), now leading the DNP research team at the University of Rostock. Collaborates closely with LIKAT on catalytic and materials projects. His group actively develops open-access publishing platforms like Magnetic Resonance and hosts international conferences. Labs/Teams: The Corzilius group at the Institute of Chemistry (Rostock) specializes in NMR method development and applications. Associated with LIKAT for interdisciplinary catalysis research.