Tommi Jaakkola

Tommi Jaakkola is the Thomas Siebel Professor of Electrical Engineering and Computer Science and the Institute for Data, Systems, and Society at the Massachusetts Institute of Technology. He received his MSc in theoretical physics from Helsinki University of Technology in 1992 and his PhD from MIT in computational neuroscience in 1997. After completing a postdoctoral position in computational molecular biology as a DOE/Sloan fellow at UCSC, he joined the MIT EECS faculty in 1998.

His research advances how machines can learn, predict or control, and do so at scale in an efficient, principled, and interpretable manner. His work in machine learning extends from foundational theory to modern applications, focusing especially on statistical inference and estimation tasks that lie at the heart of complex learning problems. He designs new methods, theory and algorithms to automate the use and generation of semi-structured data such as natural language text, images, molecules, or strategies.

Jaakkola applies and develops algorithms to solve multi-faceted recommender, retrieval, or inferential tasks (particularly in biomedical contexts), design and optimize molecules or reactions for drug design, and model strategic, game theoretic interactions. His recent work heavily focuses on diffusion models, protein structure prediction, molecular design, and generative AI, with significant publications in top conferences including ICML, NeurIPS, and ICLR.

His scientific contributions span multiple disciplines with significant impact in both theoretical machine learning and practical applications in computational biology and chemistry, including notable work on antibiotic discovery published in Cell.

• Current advisees: Julia Balla, Bowen Jing, Hannes Stärk, Peter Holderrieth, Chenyu Wang
• Recent graduates: Gabriele Corso (Boltz PBC), Ezra Erives (DE Shaw), Jason Yim (Xaira)

Jaakkola maintains an active research program through MIT's Computer Science and Artificial Intelligence Laboratory (CSAIL) and the Institute for Data, Systems, and Society (IDSS), with his office located in the Stata Center (32-G470). His work bridges theoretical machine learning with practical applications, making significant contributions to both the academic field and potential real-world impact in healthcare and drug discovery.