معرفی
Lee Miles is a Research Fellow at the School of Biological Sciences, Monash University. His research focuses on muscle biology, genetic disorders, and CRISPR/Cas9 gene editing techniques, with a particular emphasis on zebrafish models to study muscular dystrophies and proteostasis networks. He has contributed to projects analyzing muscle homeostasis mechanisms and developing gene-editing protocols.
- Lead researcher in projects: 'Testing of a VUS in distal myopathy and neuropathy' (2024–2026) and 'Functional evaluation of UBA5 variants' (2025–2027).
- Published in high-impact journals like Nature Communications and Science Translational Medicine.
Research interests include understanding genetic mutations' impact on muscle function and developing therapeutic strategies using CRISPR-based tools. Recent work explores FKRP-dependent glycosylation pathways and sarcomere contractility disruptions.
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