معرفی
Laura Sirucek is a Postdoctoral Fellow at the Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Denmark. She works at the Center for Neuroplasticity and Pain (CNAP), focusing on pain neuroplasticity research. Her work integrates various methodologies including magnetic resonance spectroscopy, psychophysics, and transcranial magnetic stimulation combined with electroencephalography to better understand chronic pain mechanisms.
Dr. Sirucek completed her educational journey at the University of Zurich, earning a Bachelor of Science in Biology (2016), a Master of Science in Biomedicine (2018), and a PhD in Neuroscience (2023). Her doctoral research focused on "Spinal and Supraspinal Sensitization in Chronic Pain – Chasing Mechanisms." She also serves as Co-Chair of the IASP Early Career Network Communication Committee for the International Association for the Study of Pain.
Dr. Sirucek's research primarily centers on chronic pain mechanisms, with special emphasis on chronic low back pain and Complex Regional Pain Syndrome. Her work investigates endogenous pain modulation systems, particularly conditioned pain modulation and descending pain pathways. She employs advanced neuroimaging techniques like magnetic resonance spectroscopy to examine neurotransmitter dynamics in pain-relevant brain regions such as the periaqueductal gray. Her research also explores pain phenotyping, sensory profiling, and the identification of biological subgroups in chronic pain conditions to advance personalized medicine approaches.
Her publication record demonstrates a consistent focus on pain mechanisms and assessment methodologies. Recent work examines neurotransmitter dysregulation in chronic pain, methodological improvements in brainstem imaging, and the identification of biological subgroups in pain conditions through transcriptomic profiling. Her research bridges basic neuroscience with clinical applications, aiming to improve pain diagnosis and treatment through a better understanding of underlying mechanisms.
Dr. Sirucek actively contributes to the pain research community through her role with the IASP Early Career Network. While specific grant information isn't detailed in the provided materials, her extensive publication record across multiple high-impact journals suggests successful research funding. She collaborates with researchers across institutions, particularly with Petra Schweinhardt's lab at Aalborg University and researchers at the University of Zurich.
Her work is conducted primarily through the Center for Neuroplasticity and Pain at Aalborg University, where she is part of a multidisciplinary team investigating pain mechanisms using advanced neuroimaging, psychophysical testing, and molecular approaches. Her recent work on transcriptomic profiling indicates expanding research into the molecular underpinnings of pain conditions.
