معرفی
Professor Kay Double is a member of the Brain and Mind Centre and the Theme of Neuroscience within the School of Medical Sciences at the University of Sydney. Her research focuses on the interplay between neuropathological findings and quantitative neurochemistry, particularly investigating disease mechanisms in Parkinson’s disease. She has been funded by prestigious fellowships including the Alexander von Humboldt Foundation and consecutive Australian Research Fellowships. Her work challenges previous dogma about neuromelanin’s role in Parkinson’s, demonstrating its neuroprotective function in healthy cells and its dysregulation in disease contexts.
Her current research projects explore copper dyshomeostasis and SOD1 proteinopathy in Parkinson’s and ALS, emphasizing translational research applications. Collaborations include interdisciplinary teams working on molecular pathways, diagnostic tools, and therapeutic strategies. Key approaches in her work include aetiological studies, cellular metallation analysis, and 3D neurochemical imaging.
Scientific Awards:
- Alexander von Humboldt Research Fellowship (Germany)
- Australian Research Fellowships
Advising and Grants: Professor Double advises current PhD student Anne LI. She has secured grants from organizations like the National Health and Medical Research Council (NHMRC), Motor Neurone Disease Research Institute of Australia, and the University of Sydney. Her grants include projects on SOD1 assays, copper pathways, and Parkinson’s diagnostics.
Labs/Teams: She is part of the Brain and Mind Centre, collaborating with researchers such as Dr. Hare, Dr. Trist, and Dr. Genoud on projects involving metal-binding proteins, neurodegenerative mechanisms, and translational neuroscience.
