معرفی
Dr. Benjamin Trist is a Postdoctoral Research Associate at the University of Sydney, affiliated with the School of Medical Sciences and the Brain and Mind Centre. His multidisciplinary research bridges biochemistry and neuroscience, focusing on neurodegenerative diseases such as Parkinson's disease and amyotrophic lateral sclerosis (ALS).
Education:
- PhD (2019), University of Sydney
- BSc (Honours, 2014), University of New South Wales
His work investigates biochemical mechanisms of neuron death, particularly misfolded superoxide dismutase 1 (SOD1) proteinopathy, using post-mortem human tissues, induced pluripotent stem cells, and rodent models. Key themes include metal dyshomeostasis, oxidative stress, and subgroup classification of neurological diseases based on tractable mechanisms.
Research trends from publications: Recent work focuses on copper dyshomeostasis in Parkinson's disease, novel fluorescent copper sensors, SOD1 neurotoxicity mechanisms, and cross-disease proteinopathy analysis. Earlier studies explored oxidative stress, metallation analysis, and structural imaging of SOD1.
Scientific Awards:
- Brain and Mind Centre Research Excellence and Impact Award (2022, 2018)
- Nina Buscombe Award (2022, 2019)
- Best ECR presentations (2022, 2021)
- Mark Rowe Award (2018)
- Professor John Irvine Hunter Prize (2017)
- Parkinson’s NSW Young Researcher of the Year (2016)
Dr. Trist supervises honours and doctoral students and has secured grants from the Brain and Mind Centre, Motor Neurone Disease Research Institute of Australia, and the Neil and Norma Hill Foundation. He is a member of the Brain and Mind Centre and Charles Perkins Centre at the University of Sydney.
