معرفی
Prof. Dr. Kai Tittmann is a Professor at the University of Göttingen and MPI-NAT Fellow leading the Department of Molecular Enzymology within the Göttingen Center of Molecular Biosciences (GZMB). His research is based at the Albrecht-von-Haller-Institute for Plant Sciences at the University of Göttingen.
Professor Tittmann's research focuses on the molecular reaction mechanisms of enzymes (biocatalysts). His work particularly emphasizes enzymes with vitamin-derived cofactors, metal ions, and Schiff base-forming enzymes. His laboratory employs a multidisciplinary approach combining high-resolution X-ray crystallography, steady-state and transient kinetic methods, NMR spectroscopy, and theoretical studies to characterize enzyme reaction intermediates.
The knowledge gained from these mechanistic studies is directly applied to redesign enzymes for biocatalytic applications and drug design. This translational approach bridges fundamental biochemical understanding with practical applications in biotechnology and medicine. His work contributes significantly to the scientific community at the intersection of structural biology, enzymology, and biocatalysis.
