معرفی
Associate Professor Julia Pagan leads the Targeted Protein Degradation lab at the School of Biomedical Sciences, The University of Queensland. With a PhD from UQ, her research focuses on the ubiquitin proteasome system (UPS) in regulating cellular homeostasis through centrosome, microtubule, and mitochondrial quality control. Her work has implications for cancers, neurodegenerative disorders, and mitochondrial diseases.
- Bachelor of Science (UQ)
- Bachelor (Honours) of Science (Advanced) (UQ)
- Doctor of Philosophy (UQ)
Research Interests: Investigates UPS mechanisms in organelle regulation, particularly:
- Mitochondrial biology and mitophagy receptors (BNIP3/NIX)
- Centrosome-microtubule dynamics in cell division
- Ubiquitin ligase pathways in disease contexts
- Therapeutic targeting of protein degradation
Publication Trends: Recent articles (2023-2025) emphasize mitophagy regulation, mitochondrial diseases, and AI-driven cancer stress assays. Earlier work (2009-2018) explores centrosome biology, DNA repair, and UPS roles in heart disease and neurodevelopment.
Scientific Awards:
- ARC Future Fellowships (2019-2023)
Supervision & Grants: Mentors PhD students in mitochondrial diseases and organelle regulation. Current grants include NHMRC IDEAS Grants (2023-2025) and Australian Functional Genomics Network funding (2025-2026). Former grants targeted Parkinson's disease, cardiac stress responses, and DNA replication defects.
