معرفی
Wade Harper, Ph.D., is the Bert and Natalie Vallee Professor of Molecular Pathology and Professor of Cell Biology at Harvard Medical School, where he chairs the Department of Cell Biology. He earned his Ph.D. in Chemistry from Georgia Institute of Technology and conducted postdoctoral work at Harvard Medical School. His career includes faculty positions at Baylor College of Medicine prior to joining Harvard.
Dr. Harper's research focuses on cellular homeostasis, ubiquitin-proteasome systems, and autophagy-lysosome pathways, employing quantitative proteomics and imaging to study neurodegenerative diseases like Parkinson's and Alzheimer's. His lab investigates PARKIN ubiquitin ligase mechanisms in mitochondrial quality control and develops human protein interaction networks.
His recent publications emphasize advanced proteomic techniques applied to neurodegeneration, organelle dynamics, and cellular stress responses. Research themes include ubiquitin signaling, mitophagy regulation, ribosome biology, and protein quality control under metabolic stress.
Dr. Harper directs an interdisciplinary lab collaborating extensively with the Gygi Lab at Harvard Medical School, leveraging cutting-edge biochemical and computational approaches to map proteomic landscapes in health and disease.
