معرفی
Jianhua Li, PhD, MD is a Professor in the Department of Medicine, Division of Cardiology at Pennsylvania State University's College of Medicine, affiliated with the Penn State Heart and Vascular Institute. With an h-index of 27 and 2066 citations, he has produced 90 research outputs since 1996, including 83 articles, 5 review articles, 1 conference article, and 1 editorial.
His research focuses on Cardiovascular Physiology, particularly the Exercise Pressor Reflex in Peripheral Artery Disease. His work investigates neural mechanisms involving Muscle Afferent Neuroscience, Baroreflex function, and Dorsal Root Ganglion Neuroscience. He studies how muscle afferents contribute to sympathetic responsiveness during exercise in conditions of arterial occlusion and ischemia-reperfusion.
Dr. Li's research demonstrates how peripheral artery disease amplifies exercise pressor reflex through mechanisms involving acid-sensing ion channels (ASICs), P2X receptors, and inflammatory cytokines in dorsal root ganglion neurons. His work has significant implications for understanding cardiovascular complications during exercise in patients with vascular diseases.
His laboratory has received continuous funding from the National Heart, Lung, and Blood Institute, with active projects extending through 2024. His research employs rat models to investigate molecular and physiological mechanisms underlying cardiovascular regulation during exercise in pathological conditions.
- Principal Investigator on multiple NIH-funded projects
- Active research extending through 2024
- 9 research projects completed since 2004
