Urs Leuenberger

Dr. Urs Leuenberger is a Professor in the Department of Medicine Division of Cardiology at Penn State University, serving as Associate Director of both the Penn State Clinical and Translational Science Institute (CTSI) and Penn State Heart and Vascular Institute. His work intersects cardiovascular physiology, autonomic regulation, and translational medicine.

• Research Foci: Muscle Sympathetic Nerve Activity, Blood Pressure Control, Coronary Circulation, Peripheral Artery Disease, Intermittent Hypoxia, Exercise Reflexes
• Key Projects: National Heart, Lung, and Blood Institute-funded studies on circulatory control mechanisms, chemoreflex responses, and metabolic vasodilation inhibition

Recent Publications (2023–2025) address:

• Intermittent hypoxia effects on neurocirculatory responses
• Dietary nitrate supplementation for coronary blood flow optimization
• Autonomic dysfunction in type 2 diabetes during exercise
• Hyperoxia impacts on cardiovascular tone
• Exercise hemodynamics in peripheral artery disease

Collaborations span human physiology core laboratories with technical expertise in autonomic function assessment, limb blood flow measurement, and metabolic stress testing.