Jason Farrar

Dr. Jason Farrar is an Assistant Professor in the Department of Pediatrics at the University of Arkansas for Medical Sciences (UAMS) and practices at Arkansas Children's Hospital. His research focuses on bone marrow failure syndromes, particularly Diamond Blackfan anemia (DBA), and pediatric leukemia, with a strong emphasis on genomic and molecular mechanisms. He splits his time between clinical care (20%) at ACH's Hematology-Oncology Clinic and research (80%) at the UAMS Winthrop P. Rockefeller Cancer Institute. His work includes studying the genetics of DBA, developing therapies for rare blood disorders, and collaborating on initiatives like the NCI's TARGET program to advance treatments for childhood cancers like AML. Dr. Farrar's educational background includes Rhodes College (Biology), UAMS College of Medicine (MD), residency at Children’s Hospital of Wisconsin, and fellowship at Johns Hopkins University and the National Cancer Institute.

Research interests span DBA pathogenesis, epigenetic regulation in cancer, and translational therapies for AML. He leads studies on novel treatments (e.g., eltrombopag for aplastic anemia) and leverages genomic techniques to identify biomarkers and therapeutic targets. His clinical work includes managing pediatric patients with hematological disorders like sickle cell anemia and leukemia.

Key contributions include defining genetic drivers of DBA, characterizing molecular subtypes of AML, and advancing understanding of bone marrow failure syndrome complications such as cancer predisposition. Collaborations with national networks enhance his translational research impact.