James Murphy

James Murphy is a Research Professor in the Drug Discovery Biology department at Monash University. His work focuses on molecular mechanisms of cell death, particularly necroptosis, with contributions to understanding cancer biology, immunology, and therapeutic target identification. He serves on editorial boards for journals including Cell Death and Differentiation, Trends in Biochemical Sciences, and Structure. His research aligns with UN Sustainable Development Goals related to health and innovation. Recent studies explore necroptotic pathway expression mapping, cancer cell invasion dynamics, and MLKL-mediated cell death mechanisms. Murphy collaborates internationally on projects investigating cell signaling pathways and their clinical applications.

• Editor in Chief: Biochemical Society Transactions (2023-2025)
• Editorial Board Member: Science Signaling, Structure, and Cell Death and Differentiation

Key research themes include necroptosis regulation, cancer metastasis, and drug discovery strategies targeting cell death pathways. His work bridges basic science with translational applications in oncology and immunotherapy.