معرفی
Dr. James Burchfield is a Research Fellow and Group Leader of the Molecular Imaging Group at the University of Sydney's School of Life and Environmental Sciences. His primary roles include leading research on molecular mechanisms of metabolic disorders, particularly insulin resistance and mitochondrial dysfunction. He oversees a multidisciplinary team focused on integrating advanced imaging techniques with cellular biology.
Education: BSc Honours (University of Sydney, 2000), PhD (University of NSW, 2008), and postdoctoral research at Garvan Institute, UNSW, and the lab of Professor David James. His work bridges molecular biology, lipidomics, and computational biology to address cardiometabolic diseases.
Research interests center on insulin signaling pathways, mitochondrial-ER lipid interactions, and the development of novel imaging tools. Key innovations include ThunderBolt (a data-sharing platform) and advanced methods for quantifying mitochondrial lipidomes. His lab investigates obesity, diabetes, and metabolic syndrome using systems biology approaches.
Grant funding includes NHMRC Ideas Grants (2021) and ARC Discovery Projects (2020), focusing on mitochondrial stress pathways and imaging infrastructure. Collaborations span academia and industry to translate discoveries into clinical applications.
- Advises 9 current students (PhD, Honours, and visiting researchers).
- Labs: Charles Perkins Centre (D17), specializing in molecular imaging and metabolic cybernetics.
- Publications emphasize insulin signaling defects, lipidomics, and computational tools for omics data.
