Ingo Greger

Ingo Greger is a Researcher at the MRC Laboratory of Molecular Biology, focusing on AMPA-type glutamate receptors central to excitatory neurotransmission and synaptic plasticity. His work integrates structural biology, electrophysiology, and computational simulations to elucidate receptor biogenesis and function.

Research highlights include

• Structural studies (X-ray crystallography, cryo-EM) of AMPA receptor tetramers and hetero-octamers
• Investigations into allosteric modulation by interacting proteins and TARPs
• Mechanistic insights into receptor anchoring, gating, and synaptic targeting

Recent publications (2012-2023) demonstrate expertise in combining structural analysis with functional electrophysiology to understand receptor dynamics in synaptic transmission. The group employs advanced techniques like super-resolution microscopy and brain slice recordings to study receptor roles in cognitive processes.

Current team members include Ondrej Cais, Kieron Cartwright, and other researchers collaborating on molecular neuroscience projects.