Brent Doiron is a Professor at the University of Chicago, holding appointments in the Departments of Neurobiology and Statistics, and serving on the Committee on Computational and Applied Mathematics (CCAM). His research integrates nonlinear dynamics and statistical mechanics to study neural circuit variability, focusing on mechanisms underlying neural coding and network learning through collaborations with experimentalists in sensory systems. Education: PhD in Physics (University of Ottawa, 2004) Postdoc: Center for Neural Science at New York University (2017) Previous Roles: Mathematics Professor at University of Pittsburgh (2007-2020), Co-Director of Neural Computation Program at Carnegie Mellon Neuroscience Institute Research interests center on neuronal population dynamics, recurrent circuit mechanisms, and computational neuroscience. Current work investigates correlated variability in cortical networks, inter-areal communication, and stochastic spiking models. Recent publications emphasize cortical stability/gain modulation, asynchronous/synchronous activity balance, and Bayesian inference frameworks. Key themes include sensory processing, network plasticity, and dimensionality reduction in neural coding. Scientific Awards Alfred P. Sloan Research Fellowship in Neuroscience Vannevar Bush Faculty Fellowship Chancellor’s Distinguished Research Award (University of Pittsburgh) Active grants include NIH R01 and R90/T90 awards for neuronal dynamics research and computational neuroscience training programs.
Marc V Fuccillo is an Associate Professor of Neuroscience at the Perelman School of Medicine, University of Pennsylvania, where he leads a research laboratory focused on understanding the neural circuit mechanisms underlying behavioral control. His work bridges molecular, synaptic, and behavioral approaches to investigate how striatal circuits regulate mouse behavior from simple motor patterns to complex goal-directed actions. Fuccillo holds dual appointments in the Neuroscience and Cell and Molecular Biology Graduate Groups at Penn and maintains an active laboratory investigating the synaptic and circuit basis of neuropsychiatric disorders. Education: B.A. in Molecular and Cellular Biology and Music Performance (Violin) from Brown University (1998) Ph.D. in Developmental Genetics from New York University School of Medicine (2007) M.D. from New York University School of Medicine (2008) Fuccillo's research centers on the synaptic and circuit mechanisms of behavioral control, with particular emphasis on striatal circuits. His laboratory employs a range of technologies including mouse genetics, in vitro electrophysiology, in vivo imaging, and quantitative behavioral analysis to explore how neural circuits of the striatum regulate behavior and how disruptions in these circuits contribute to neuropsychiatric disorders. His work has particularly focused on autism-associated abnormalities in behavioral control, examining how synaptic adhesion molecules like neuroligins and neurexins shape circuit function and behavior, with significant findings regarding D1 dopamine receptor positive medium spiny neurons in the nucleus accumbens. Analysis of Fuccillo's recent publications reveals a strong focus on striatal circuit function across multiple dimensions. His work spans molecular neuroscience (examining synaptic adhesion molecules), cellular physiology (studying specific neuron types in striatal circuits), systems neuroscience (mapping circuit connectivity), and behavioral neuroscience (quantifying motor learning and decision-making). A unifying theme is how disruptions in specific molecular pathways lead to circuit-level abnormalities that manifest as behavioral phenotypes relevant to neuropsychiatric disorders, with particular attention to autism, OCD, and schizophrenia models. Scientific Recognition: Publications in high-impact journals including Nature Neuroscience, Current Biology, Cell Reports, and Neuron Research supported by multiple NIH grants including NIMH F32, NIMH K01, and HHMI Gilliam Fellowship awards for lab members Fuccillo actively mentors a diverse group of trainees including postdoctoral fellows, graduate students, and undergraduates. His laboratory has produced numerous successful alumni who have gone on to faculty positions, medical residencies, and graduate programs at prestigious institutions. His mentoring approach emphasizes technical skill development across multiple neuroscience disciplines while fostering independent scientific thinking. Current research in his lab is supported by NIH funding focused on understanding the molecular architecture of striatal circuits and their role in behavioral control, with three major research directions exploring molecular logic of striatal circuits, circuit mechanisms of behavioral control, and striatal dysfunction in neuropsychiatric disease models. The Fuccillo Laboratory operates within the Department of Neuroscience at the University of Pennsylvania, with access to state-of-the-art facilities for molecular, electrophysiological, imaging, and behavioral neuroscience research. The lab maintains active collaborations with other neuroscience research groups at Penn and beyond, creating a rich intellectual environment for studying the neural basis of behavior. Current research directions include investigating whether there is a molecular logic to striatal circuit composition, how striatal circuits shape behavioral control, and what mouse models of autism, schizophrenia, and OCD can reveal about striatal circuit dysfunction in disease pathophysiology.
Benjamin Machta is an Assistant Professor of Physics at Yale University, affiliated with the Department of Physics and the QBio Institute. He holds a BS from Brown University and a PhD from Cornell University, followed by a postdoctoral fellowship at Princeton University. His research focuses on applying theoretical physics to understand biological systems, particularly leveraging statistical physics and information theory to study biological membranes near critical points and the energetic constraints of biological signaling. Education: BS in Physics (Brown University), PhD in Physics (Cornell University), Postdoc at Princeton University (Lewis-Sigler Theory Fellow). Research Interests include: membrane criticality, phase transitions in biological systems, information-theoretic limits in organism function, and energy dissipation in biological processes. His work often bridges theoretical models with experimental data, such as collaborations with Sarah Veatch’s lab on membrane phase behavior. Publications highlight themes like membrane criticality, protein phase separation, and energy constraints in signaling. His group’s current projects explore cochlear mechanics, thermodynamic control in biological systems, and the role of criticality in sensory systems. Awards: 2019 Simons Investigator Award. Lab Affiliations: QBio Institute and Department of Physics at Yale, located in YSB-C164. Group members include postdocs Isabella Graf and Michael Abbott, and graduate students Asheesh Momi, Mason Rouches, and others.
Colin J Akerman is Professor of Neuroscience and Group Leader in the Department of Pharmacology at the University of Oxford, concurrently serving as Corange Fellow and Medical Tutor at Corpus Christi College. His research investigates fundamental mechanisms of synaptic circuit formation and plasticity, with direct implications for epilepsy, dementia, and schizophrenia through multidisciplinary approaches integrating electrophysiology, optical imaging, and computational modeling. His primary research interests encompass Synaptic Plasticity, Neural Circuit Formation, and Excitatory-Inhibitory Balance, with specific focus on neuronal progenitor influences on connectivity, chloride dynamics in inhibitory transmission, and learning mechanisms in disease contexts. The lab employs custom-built equipment and molecular tools to probe synaptic function across in vivo , in vitro , and in silico platforms, emphasizing how activity-dependent processes shape neural networks during development and disease. Recent publications (2023-2025) reveal strong thematic convergence on intracellular chloride regulation in sleep-wake cycles, cortical circuit assembly from embryonic progenitors, and innovative optical tools for neural monitoring. This work bridges molecular neuroscience with systems-level understanding of synaptic plasticity, particularly regarding ionic mechanisms in epilepsy and sleep homeostasis. No scientific awards or fellowships are explicitly documented in the source materials. Professor Akerman currently mentors four PhD students (Vourvoukelis, Selfe, Wang, Gemayel) and multiple postdoctoral researchers, having previously trained scientists now leading independent groups in Toronto, Edinburgh, Cape Town, Oxford, and London. His research is funded by the European Research Council, Innovative Medicines Initiative, and Wellcome Trust, supporting investigations into synaptic mechanisms underlying neurological disorders. The Akerman Group, established in 2008, operates as an integrative neuroscience hub within Oxford's Pharmacology Department. The 10-member team combines expertise in patch-clamp electrophysiology, optogenetics, multiphoton imaging, and computational modeling, with current projects spanning neuronal progenitor biology, inhibitory synaptic plasticity, and learning rule implementation in neural networks. The lab emphasizes technical innovation, regularly developing custom instrumentation and molecular tools for neural observation and manipulation.
Marco Fritzsche is a Professor of Biophysical Immunology at the University of Oxford. He serves as the Scientific Director of the Oxford-ZEISS Centre of Excellence and leads the Biophysical Immunology Laboratory (www.bpi-oxford.com), which operates at the intersection of biophysics and immunology. BSc in Mathematics (2003–2006), University of Saarbrücken BSc in Physics (2003–2006), University of Saarbrücken MSc in Theoretical Physics (2006–2008), University of Saarbrücken PhD in Experimental Physics and Biology (2008–2012), University College London His research focuses on biophysical and mechanobiological mechanisms governing immune responses in health and disease. The BPI Laboratory develops advanced microscopy technologies to study these processes, integrating theoretical physics with experimental immunology. Recent publications highlight his work in quantitative imaging of biomolecular organization , traction force microscopy for immune cell dynamics, and trans-synaptic vesicle analysis in T-cell interactions. His studies bridge disciplines like biophysics, immunology, and cell mechanics. Rosalind Franklin Kennedy Trust Research Fellow The BPI Laboratory collaborates with institutions such as the Howard Hughes Medical Institute Janelia Farm and the Rosalind Franklin Institute . His roles include leadership in the Oxford-ZEISS Centre of Excellence and contributions to cutting-edge immunology research.
University of California, Los AngelesUnited States
Istvan Mody is a Professor at the University of California, Los Angeles (UCLA) with appointments in the Department of Neurology and Department of Physiology . His research focuses on synaptic signaling in health and disease, including mechanisms of GABAergic transmission, calcium homeostasis, and their roles in neurological disorders such as epilepsy, Alzheimer's disease, Huntington's disease, stress, alcoholism, and postpartum depression. He utilizes advanced techniques like patch-clamp electrophysiology, neuroanatomical and immunohistochemical methods, and molecular biology in animal models and human brain tissue . Research Interests: Dr. Mody investigates the physiology, pharmacology, and pathology of synaptic transmission and extrasynaptic receptor activation , with a particular emphasis on GABA(A) receptors and their subunit-specific modulation. His work explores how disruptions in excitation-inhibition balance contribute to neurological diseases, including mechanisms of tonic inhibition , calcium signaling , and neurosteroid interactions . He also studies the effects of chronic stress and hormonal fluctuations on neural excitability and behavior. Publications Trends: Recent studies highlight his work on gamma oscillations in Alzheimer's models, microglial dynamics , and rehabilitation strategies for stroke. His lab develops optical tools like dqGEVI for neuronal activity monitoring and investigates human brain organoids to model network dysfunction in epilepsy and intellectual disability. Laboratory Location: 635 Charles Young Dr S, Los Angeles, CA 90095, United States.
Dr. Rodolfo J. Flores serves as an Assistant Professor in the Department of Psychology within the College of Liberal Arts at the University of Texas at El Paso (UTEP). His primary research investigates neuromodulator function in the prefrontal cortex, with emphasis on acetylcholine and dynorphin systems during motivational conflict, stress responses, and addiction pathways. He employs advanced optogenetic and biosensor technologies to dissect neural circuitry underlying psychiatric conditions. Dr. Flores earned his Ph.D. in Social Cognitive and Neuroscience from UTEP in 2019, followed by postdoctoral training at the National Institute of Mental Health (NIMH). His work bridges molecular neuroscience with behavioral outcomes, focusing on how stress and substance exposure alter prefrontal cortical function. His research portfolio demonstrates consistent high-impact publication in top neuroscience journals including Nature Neuroscience , Neuron , and Psychoneuroendocrinology . Current work examines opioid neuropeptide dynamics, nicotine-alcohol interactions, and sex-specific hormonal influences on addiction behaviors. Methodologically, he specializes in genetically encoded biosensors and circuit-level manipulations to study threat processing and reward pathways. Dr. Flores teaches graduate and undergraduate courses including PSYC 4341 (Motivation & Emotion), thesis/dissertation supervision (PSYC 5395/6395), and research applications courses. His lab actively trains students through undergraduate research (RSRC 4033) and independent study opportunities (PSYC 4352).
Virginia Polytechnic Institute and State UniversityUnited States
Matthew W. Buczynski is an Assistant Professor at the School of Neuroscience , part of the College of Science at Virginia Tech . Holding a Ph.D. in Biochemistry from the University of California San Diego (2008) and postdoctoral training at The Scripps Research Institute (2009-2016), he joined Virginia Tech in August 2016 after completing his postdoctoral fellowship. Education: B.S. in Chemistry, University of Michigan , 2001 Ph.D. in Biochemistry, University of California San Diego , 2008 Postdoctoral Training, The Scripps Research Institute , 2009-2016 Dr. Buczynski’s research program focuses on identifying novel druggable targets for addiction and neurological disorders through mass spectrometry and behavioral pharmacology . His work integrates chemical biology , molecular pharmacology , and in vivo microdialysis to study molecular changes in the brain during chronic drug exposure. Key areas include nicotine dependence , ethanol withdrawal , and cross-talk between pain and addiction mechanisms. His recent publications highlight endocannabinoid system modulation , TRPV1/TRPA1 receptor activation in pain, and diacylglycerol lipase (DAGL) mechanisms in nicotine withdrawal. He employs both self-administration and forced exposure models to validate therapeutic targets. Prospective students can contact him directly through his lab’s website .
Dr. Teresa Puthussery is an Associate Professor in the School of Optometry & Vision Science at the University of California, Berkeley. Her research focuses on retinal neurobiology and neurophysiology, investigating how visual signals are encoded in healthy retinas and disrupted during degeneration. She uses advanced techniques like patch-clamp electrophysiology, immunohistochemistry, and microscopy to study retinal circuits, neurotransmitter receptors, and ion channels. Dr. Puthussery teaches courses on vision science anatomy, physiology, and problem-based learning, including VISION SCIENCE 206B/C and 260C. Her research explores questions such as how retinal neurons extract motion/spatial details, how photoreceptor mutations cause degeneration, and how inner retinal circuits adapt post-photoreceptor loss. Recent work includes studies on ON-type direction-selective ganglion cells, optogenetic therapy for vision restoration, and calcium dynamics in foveal ganglion cells post-degeneration. She collaborates on projects involving primate and rodent models, contributing to understanding retinal disease mechanisms and therapeutic targets. Dr. Puthussery’s lab (retinalab.berkeley.edu) emphasizes translational research, bridging basic science and clinical applications. Her work has been published in journals like Nature and Cell Reports , with a focus on retinal degeneration, synaptic plasticity, and optogenetic interventions. She actively participates in training future vision scientists through Berkeley’s Optometry program and oversees GSI affairs as a faculty advisor.
Alicia Che is an Assistant Professor of Psychiatry at Yale University School of Medicine and serves as Director of Graduate Admissions for the Interdepartmental Neuroscience Program. She joined the Yale Department of Psychiatry in 2021 after completing her postdoctoral fellowship with Dr. Natalia De Marco García at Weill Cornell Medical College and Dr. Gord Fishell at NYU. Her research is conducted through the Che Lab at Yale, where she investigates how early life experiences impact brain circuit assembly and mature function in models of psychiatric illness. Yale School of Medicine, Department of Psychiatry Interdepartmental Neuroscience Program Center for Brain & Mind Health Division of Molecular Psychiatry Wu Tsai Institute Yale Center for the Science of Cannabis and Cannabinoids Dr. Che earned her Ph.D. in Physiology and Neurobiology from the University of Connecticut in 2014, where she worked in the laboratory of Dr. Joseph LoTurco. She received her B.S. with triple majors in Biology, Physics, and Physical Chemistry from Pacific Lutheran University in Washington state in 2009. Her research focuses on understanding developmental trajectories following early life experiences to develop diagnostics and early interventions for psychiatric illnesses. Dr. Che's research examines how sensory inputs, social bonding, stress, and substance exposure impact brain development. She employs a multi-dimensional approach to assess transcriptional, circuit, neuronal activity, and behavioral changes across the entire developmental timeline. Her lab currently focuses on four specific areas: the role of oxytocin in social behavior development, circuit dysfunction in PTSD, early-life cannabinoid exposure effects, and the impact of early life stress on development and adulthood. She utilizes advanced techniques including mouse genetics, slice electrophysiology, and longitudinal in vivo 2-photon imaging on behaving animals. Her most recent publications demonstrate significant contributions to understanding neural circuit development, PTSD mechanisms, and the effects of early life experiences on brain function. Her work spans from molecular neuroscience to behavioral outcomes, with publications in top journals including Nature, Neuron, and Nature Communications. Her research has revealed important insights into how translaminar neuronal activity strengthens cortical columns, how oxytocin facilitates social touch development, and how PTSD affects brain transcriptomics. NARSAD Young Investigator Award (2020) K99/R00 Pathway to Independence Award from NINDS (2019) Dr. Che's work has significant implications for understanding and treating neurodevelopmental disorders, PTSD, and the consequences of early life experiences on mental health. She collaborates extensively with researchers across Yale and beyond, with frequent co-authorship with colleagues including Lin Lin, Alex Kwan, and Christopher Pittenger. Her research program bridges basic neuroscience with clinical applications, aiming to translate findings into potential interventions for psychiatric conditions.
University of California, Los AngelesUnited States
Joel Zylberberg is an Adjunct Assistant Professor at the University of California, Los Angeles (UCLA), affiliated with the Department of Ophthalmology within the School of Medicine . His research bridges Computational Neuroscience , Neural Networks , and Machine Learning , focusing on how neural activity and biological mechanisms inform artificial intelligence and visual cortex dynamics . Joel's work explores retinal computation , population coding , and neural adaptation , often analyzing mouse visual cortex and neurophysiological data . His recent publications highlight trends in dynamic retinal processes , stimulus-driven network topology , and brain-inspired machine learning , emphasizing the interplay between biophysics and computational modeling . Collaborators include Greg Field (UCLA), Richard Born (Harvard), and Michael DeWeese (UC Berkeley), with affiliations spanning institutions like University of Washington and University of California, San Diego (UCSD). His work appears in journals such as Nature Neuroscience , Neuron , and PLOS Computational Biology .
Prof. Stephan J. Sigrist is a Full Professor of Genetics at the Institute of Biology, Free University of Berlin. His lab focuses on synaptic active zone architecture, neuroplasticity, and aging-related neurodegeneration. He leads the Collaborative Research Center 958 on Membrane Scaffolding and co-directs NeuroCure, a DFG Cluster of Excellence at Charité. Education: PhD in Molecular Genetics (1997) and Habilitation (2005) from the University of Göttingen. Positions: Einstein Professor (2014–present), Spokesperson CRC 958 (2012–present), and Co-Director NeuroCure (2009–present). Research explores presynaptic mechanisms using Drosophila and mouse models, combined with STED microscopy. Key contributions include discoveries of Bruchpilot's role in active zones and spermidine's protective effects against age-related synapse decline. Grants: Over €6 million in funding, including DFG CRCs, Einstein Foundation, and ERC Advanced Grant (2025). Awards: Einstein Professorship, Best Habilitation Award, EMBO/HFSP Fellowships. Collaborations span structural biology (e.g., Stefan Hell), neurophysiology (David DiGregorio), and aging research (Frank Madeo).
Manu Sharma is an Associate Professor of Neuroscience at the Brain and Mind Research Institute , Weill Cornell Medical College (2024–present). His research focuses on the molecular mechanisms underlying neurodegenerative diseases, particularly tauopathies and synucleinopathies (e.g., Alzheimer’s and Parkinson’s diseases), synaptic transmission, and protein aggregation. Education: Ph.D., University of Toronto (2005) B.Sc., University of Toronto (1998) Research Interests: Dr. Sharma investigates how physiological and pathological modifications of tau and α-synuclein proteins contribute to neurodegeneration. His work explores synaptic vesicle dynamics, chaperone-mediated protein stabilization, and the role of lysosomal pathways in disease progression. Grants: He has secured major funding as Principal Investigator and Co-Investigator from the National Institute on Aging and National Institute of Neurological Disorders & Stroke (2024–2029) for studies on tau proteostasis, synucleinopathies, and small molecule inhibitors targeting neurodegenerative pathways. Labs & Teams: Affiliated with the Brain and Mind Research Institute, Dr. Sharma collaborates on multidisciplinary projects involving synaptic biology, protein quality control, and neurodegeneration models.
Dr. Jason Yi is an Assistant Professor of Neuroscience at Washington University School of Medicine (WashU Medicine). His research focuses on understanding the molecular pathways that shape nervous system development and function, with particular emphasis on autism spectrum disorders (ASD). He leads the Yi Lab, which investigates the role of the ubiquitin ligase UBE3A in the brain and its implications for neurodevelopmental disorders. Dr. Yi received his BS in Biochemistry and Molecular Biology from Dickinson College in 2001 and his PhD in Pharmacology from Duke University in 2009. His laboratory is broadly interested in the molecular pathways that shape nervous system development and function, with the ultimate goal of understanding how dysfunction in these pathways contributes to disease. The current focus is on autism spectrum disorders (ASD), using genetic information from human patients to guide in vitro and in vivo experiments employing biochemical, genetic manipulation, cell biological, and microscopy techniques. Dr. Yi's research has significant clinical implications, particularly in understanding how UBE3A dysfunction relates to both Angelman syndrome (caused by lack of UBE3A activity) and autism (caused by excessive UBE3A activity). His lab discovered that a single phosphorylation event in UBE3A turns off its ubiquitin ligase activity, and that mutations in this site are linked to autism. This work bridges disease genetics with a mechanistic understanding of ASD neurobiology and aims to define developmental timepoints for ASD onset. Dr. Yi's research has been recognized with numerous prestigious awards: Ruth K. Broad Biomedical Research Foundation Predoctoral Fellowship (2006) F32 Kirschstein National Research Service Award (2011) Christina Castellana Postdoctoral Fellowship (2011-2014) The University of North Carolina Postdoctoral Award for Research Excellence (2015) Bridge to Independence Award, The Simons Foundation (2017) NARSAD Young Investigator Award, Brain and Behavior Research Foundation (2018) Whitehall Foundation Research Grant (2018) Alfred P. Sloan Foundation Research Fellowship (2019) Dr. Yi's research program is supported by significant grant funding from organizations including The Simons Foundation, Brain and Behavior Research Foundation, and the Whitehall Foundation. His work bridges basic molecular neuroscience with clinical implications for neurodevelopmental disorders, particularly autism spectrum disorders. Through his research, Dr. Yi is contributing to a deeper understanding of the molecular mechanisms underlying ASD, which may ultimately lead to new therapeutic approaches and interventions. The Yi Lab maintains a collaborative research environment focused on cutting-edge neuroscience techniques. The lab combines molecular, cellular, and genetic approaches to study UBE3A function and its role in neurodevelopment. Their work utilizes patient-derived genetic information to guide experimental approaches, ensuring clinical relevance to autism spectrum disorders. Dr. Yi is also actively involved in mentoring graduate students and postdoctoral fellows, contributing to the training of the next generation of neuroscientists.
Trond Vidar Hansen is a Professor at the Department of Pharmacy, University of Oslo , and leads the LIPCHEM research group . He collaborates with institutions including the University of Bergen and Vestlandets Innovasjonsselskap through the VITADEL project, which recently received NOK 5,000,000 in verification support from the Research Council of Norway. His research focuses on the synthesis and biological evaluation of specialized pro-resolving lipid mediators derived from omega-3 fatty acids, with applications in inflammation resolution, neuroinflammation, and drug development. University : University of Oslo Department : Department of Pharmacy Research Group : LIPCHEM Collaborations : University of Bergen, Vestlandets Innovasjonsselskap Research Interests : H Hansen's work centers on the organic synthesis of bioactive lipid derivatives, particularly pro-resolving mediators from omega-3 polyunsaturated fatty acids. His team investigates their roles in inflammatory disease models , neuroinflammation , and PPAR receptor activation , aiming to develop therapeutic agents for conditions like chronic pain, diabetes, and neurodegenerative disorders. The research integrates stereoselective chemistry , biochemical profiling , and pharmacological evaluation to validate these mediators' clinical potential. Recent Awards : 2025: NOK 2,000,000 verification support from Research Council of Norway 2025: Co-leader of NOK 5,000,000 VITADEL project Publications : His articles (2015–2024) reveal a focus on stereoselective synthesis of resolvins, protectins, and maresins, with applications in anti-inflammatory and neuroprotective therapies . Key subfields include omega-3 metabolite profiling , PPAR agonist design , and biosynthetic pathway elucidation , often utilizing human cell models and mouse disease models . Collaborative projects emphasize commercialization of academic research and translational medicine .
