معرفی
Ikki Sakuma is an Adjunct Assistant Professor in the Department of Internal Medicine at Yale School of Medicine, specializing in Endocrinology. His research focuses on metabolic disorders, particularly metabolic dysfunction-associated steatohepatitis (NASH), lipid metabolism, and adrenal pathology. He collaborates extensively with leading researchers like Gerald I. Shulman and Kitt Petersen. Sakuma’s work spans molecular mechanisms of liver disease, glycogen synthase inhibition in Pompe disease, and imaging-genotype correlations in adrenal tumors. His studies often employ mouse and rat models to explore therapeutic targets and metabolic pathways. Key publications address liver lipid droplet cholesterol dynamics, CAMKII signaling in hepatic metabolism, and case studies on pasireotide treatment in acromegaly. Sakuma’s research integrates clinical insights with molecular biology to advance understanding of endocrine and metabolic diseases.