معرفی
Mateus Guerra, PhD, is a Senior Staff Scientist at the Yale School of Medicine, Department of Medicine (Digestive Diseases). He holds appointments in Digestive Diseases and is affiliated with the Center for Cellular and Molecular Imaging (CCMI). His research focuses on calcium signaling pathways in liver pathophysiology, metabolic dysfunction-associated steatohepatitis (NASH), and mitochondrial biology. Guerra earned his PhD in Pharmacology from the Federal University of Minas Gerais (2010), with a visiting research stint at Università di Roma La Sapienza (2008), and earlier degrees including an MSc in Biochemical Pharmacology (2004) and BS in Pharmacy (2000).
Key research interests include the role of cytosolic calcium in hepatic metabolism, neutrophil-mediated liver injury in alcoholic hepatitis, and lipid droplet cholesterol regulation in NASH. His work integrates molecular biology, cell signaling, and advanced imaging techniques to study liver diseases. Collaborations with prominent researchers like Michael H. Nathanson and Gerald I. Shulman highlight his contributions to translational hepatology.
Guerra's lab at the CCMI explores cellular mechanisms linking metabolic stress and liver injury, with recent studies published in Proceedings of the National Academy of Sciences, Cell Metabolism, and Journal of Clinical Investigation. His research has identified novel therapeutic targets for NASH and alcohol-related liver diseases through insights into mitochondrial calcium dynamics and lipid droplet biology.
No scientific awards are explicitly listed, but his extensive publication record underscores peer recognition. He advises a collaborative network of researchers but no named students are documented here. Funding sources and grants are not specified in the provided text.