معرفی
Rafael Calais Gaspar is a Researcher in the Department of Internal Medicine at Yale School of Medicine, Yale University. He holds a PhD, MSc, and BS in Nutrition, Sports, and Metabolism Science from the University of Campinas. His work focuses on metabolic pathways, hepatic and muscle physiology, and the impact of exercise on metabolic disorders.
Key research interests include lipid metabolism, insulin resistance, NAFLD/NASH, and the molecular mechanisms governing metabolic adaptations. Collaborations with prominent researchers like Gerald I. Shulman and Mario Kahn underscore his contributions to understanding metabolic dysfunction.
Recent publications highlight breakthroughs in liver lipid droplet cholesterol's role in steatohepatitis, exercise's effect on hepatic metabolism, and SGLT2 inhibitors' cardiac effects. His studies often integrate animal models and human clinical data to explore metabolic disease mechanisms.
Gaspar's lab investigates interventions like time-restricted feeding and exercise, aiming to combat obesity, diabetes, and cardiometabolic disorders. His work bridges basic science and translational medicine, with implications for therapeutic development.