Helen Haskell Hobbs

Helen Haskell Hobbs is a Professor at the University of Texas Southwestern Medical Center and a Howard Hughes Medical Institute Investigator. Her groundbreaking research focuses on genetic mutations affecting cholesterol metabolism and liver disease, leading to significant therapeutic advancements.

• Eugene McDermott Distinguished Chair for the Study of Human Growth and Development
• Co-founder of the Dallas Heart Study
• Board Member at Pfizer

Education:

• BS - Stanford University
• MD - Case Western Reserve University School of Medicine
• Internship - Columbia-Presbyterian Medical Center
• Chief Resident - Parkland Memorial Hospital

Research Interests: Dr. Hobbs investigates genetic determinants of cardiovascular disease and fatty liver disease. Her work on PCSK9 mutations revealed mechanisms for cholesterol regulation, while PNPLA3/TM6SF2 gene studies uncovered pathways for hepatic triglyceride metabolism.

Scientific Awards:

• Breakthrough Prize in Life Sciences (2015)
• Harrington Prize for Innovation in Medicine (2018)
• Heinrich Wieland Prize (2005)
• National Academy of Medicine member (2004)
• Howard Hughes Medical Institute Investigator