معرفی
Giada De Palma is a Part-Time Assistant Professor in the Department of Medicine at McMaster University. Her research focuses on the gut microbiome, gut-brain axis, and their roles in irritable bowel syndrome (IBS), chronic abdominal pain, and neuroimmune interactions.
- Key research themes: Gut-Brain Axis, Microbiota-Host Interactions, Visceral Pain Mechanisms, Dietary Interventions in IBS
- Academic collaborations: Premysl Bercik, Elena Verdu, Stephen Michael Collins, Michael Surette, Maria Pinto-Sanchez
Her recent publications highlight lysophospholipid signaling in IBS, microbiota-induced CGRP production, and sex-dependent visceral sensitivity. She has contributed to understanding how histamine-producing gut bacteria and β-defensins influence pain and immune function. Her work also reveals microbial transfer effects on anxiety phenotypes and age-related memory decline.
Notable methodological contributions include humanized mouse models and metabolomic profiling to study microbiota-diet interactions. Current research explores probiotic interventions like Saccharomyces boulardii for gut-brain axis dysfunction.
