معرفی
Felice Elefant is Professor of Biology at Drexel University, leading research on epigenetic mechanisms in brain function and neurodegeneration. Her lab investigates histone acetylation homeostasis in cognitive processes and disease pathology.
Education:
- PhD, Temple University
- BS, George Washington University
- Postdoctoral Training: Epigenetics, University of Pennsylvania (Howard Hughes Medical Institute)
Research focuses on how disruption of histone acetylation balance contributes to cognitive impairment in neurodegenerative disorders. Current work examines specific histone acetyltransferases (HATs) like Tip60 as therapeutic targets for Alzheimer's disease, exploring mechanisms to restore epigenetic balance without side effects.
Publications demonstrate consistent investigation of Tip60's role across model organisms, with recent advances in understanding its RNA-binding functions and transcriptomic impacts in Alzheimer's pathology. Research integrates molecular profiling with behavioral analysis.
Laboratory located in PISB 312A develops innovative approaches to modulate epigenetic pathways for cognitive enhancement, emphasizing translational neuroscience applications.
