Feilim Mac Gabhann

Feilim Mac Gabhann is an Associate Professor of Biomedical Engineering at Johns Hopkins University’s Whiting School of Engineering, with a joint appointment in the School of Medicine. His expertise lies in systems pharmacology, focusing on computational modeling of therapies like antibody-drug conjugates, gene therapies, and cell transplants. He investigates the role of VEGF (vascular endothelial growth factor) in diseases such as cancer, HIV, and vascular disorders.

Education:

• Bachelor’s in Chemical Engineering (University College Dublin, 1997)
• PhD in Biomedical Engineering (Johns Hopkins University, 2006)
• Postdoctoral Fellowship in Cardiovascular Research at the University of Virginia (2006–2009)

Research Interests: Computational models to simulate therapies targeting VEGF signaling pathways, HIV pathogenesis, and cardiovascular remodeling. Projects include designing antibody-drug conjugates for cancer, simulating HIV therapies to boost host responses, and developing novel data visualization tools.

Key Contributions: His work bridges computational biology and clinical applications, supported by NIH grants and awards such as the 2012 Sloan Research Fellowship and 2016 Teaching Excellence Award. He is a core faculty member of the Institute for Computational Medicine.

Awards:

• William H. Huggins Excellence in Teaching Award (2016)
• JHU Catalyst Award (2015)
• American Physiological Society Arthur C. Guyton Award (2012)
• NIH Pathway to Independence Award (2008)

Grants & Advising: Leads projects funded by NIH, including virtual clinical trial simulations for HIV therapies. Active in mentoring students and collaborating across disciplines to advance translational medicine.

Labs & Teams: Directs the Computational Design of Therapeutics Lab, focusing on mechanistic modeling of therapeutic interventions and vascular biology. Collaborates with the Institute for Computational Medicine on interdisciplinary projects.