معرفی
Dr. Douglas Browning is a Senior Lecturer in the School of Biosciences at Aston University, affiliated with the College of Health and Life Sciences. His research focuses on bacterial gene regulation, outer membrane protein assembly in Gram-negative bacteria, and synthetic biology for recombinant protein systems. He holds a Ph.D. in Microbiology from the University of Warwick and a BSc (Hons) in Biological Sciences (Genetics) from the University of Birmingham. He is a Fellow of the Higher Education Academy (Advance HE) and a member of the Microbiology Society since 2002.
Research Interests:
- Regulation of bacterial virulence in pathogens like Escherichia coli, Klebsiella pneumoniae, and Salmonella.
- Assembly and disruption of Gram-negative bacterial outer membranes via the BAM complex.
- Engineering bacterial systems for high-yield recombinant protein production.
Funding and Awards:
- Current grants include £1.7M from BBSRC for membrane protein research and £130K for industrial collaboration on outer membrane proteins.
- Past awards include BBSRC grants totaling over £2M and industrial contracts with companies like Syngenta.
Teaching and Leadership:
He leads the MRes Research Scientist (L7 Degree Apprenticeship) program and teaches modules on molecular biology, microbiology, and biotechnology. He has held roles such as Midlands Regional Representative for the UK Research Staff Association (2020–2022).
Laboratory Team:
Current lab members include postdoctoral researchers (e.g., Dr. Alexandra Trigg) and students like Emily Baker and Gemma Allcott. Ongoing projects involve bacterial outer membrane engineering and recombinant protein optimization.
