معرفی
Diane Joseph-McCarthy is the Executive Director of the Bioengineering Technology & Entrepreneurship Center and a Professor of the Practice in Biomedical Engineering at Boston University. She holds affiliations with the Departments of Chemistry and Materials Science & Engineering. Her research focuses on computational approaches for protein-ligand interactions, drug discovery, and infectious disease modeling. Notable contributions include work on SARS-CoV-2 inhibitors, antibiotic potentiation strategies, and computational tools like E-FTMap for pharmacophore identification.
Education:
- PhD in Physical Chemistry, MIT
- B.A. in Chemistry with Computer Science minor, Boston University
Research Interests: Her work integrates chemical biology, biophysics, and computational science to address challenges in drug discovery. Key areas include:
- Fragment-based drug design
- Antiviral and antibacterial therapies
- Protein-protein interaction inhibitors
- Computational modeling of ligand binding sites
Publications & Awards: Over 150 publications span topics like SARS-CoV-2 evolution, antibiotic synergy, and machine learning in drug discovery. She is a 2023 Fellow of the American Institute for Medical and Biological Engineering and a 2016 Distinguished Alumni Speaker for BU Chemistry.
Labs/Teams: Leads the Joseph-McCarthy Group focused on computational drug design and molecular modeling. Collaborates with interdisciplinary teams across engineering, chemistry, and public health.
