Thierry Langer

Professor Thierry Langer is a Full Professor of Pharmaceutical Chemistry at the University of Vienna’s Faculty of Life Sciences (Department of Pharmaceutical Sciences). He leads research in computational drug design, with a focus on pharmacophore modeling, 3D-QSAR analysis, and AI-driven molecular design. His work bridges theoretical and experimental chemistry, addressing targets like viral proteases (e.g., SARS-CoV-2), GABA receptors, and dopamine transporters.

Research interests include:

• Pharmacophore-guided drug discovery for anti-viral and CNS therapies
• Development of next-generation computational tools (e.g., PharmacoMatch, QPhAR)
• Protein-ligand interaction modeling using neural networks and graph-based algorithms

Recent studies focus on: Inhibitors for herpesvirus nuclear egress complexes, AI-optimized antivirals, and dopamine transporter inhibitors for cognitive enhancement. His lab collaborates on projects like the NeuroDeRisk initiative to de-risk neurotoxic compounds.

Publications emphasize drug repurposing, metabolic pathway analysis, and scalable synthesis methods for promising drug candidates.