Claire van Dijk

Claire van Dijk is a researcher at Erasmus University Medical Center in the Department of Hematology. Her work focuses on understanding the cellular and molecular mechanisms underlying blood cell development and disorders, particularly using mouse models and single-cell approaches.

Her research interests include:

• Hematopoiesis and blood cell development
• Stem cell biology in the bone marrow microenvironment
• Myeloid cell function and immunology
• Mouse models of blood disorders
• Acute Myeloid Leukemia pathogenesis
• Interferon signaling in hematopoietic deterioration

Dr. van Dijk's recent publications demonstrate a strong focus on single-cell approaches to understand the bone marrow microenvironment in both healthy and disease states. Her work spans from basic stem cell biology to translational research in blood cancers, particularly acute myeloid leukemia. She frequently employs mouse models to investigate genetic and molecular mechanisms underlying hematopoietic disorders.

Her scientific contributions include:

• Developing cellular taxonomies of bone marrow stromal cells
• Investigating inflammatory niche remodeling in AML
• Studying the role of myeloid cells in interferon-mediated hematopoietic decline
• Exploring DNA repair mechanisms in aging models

Dr. van Dijk collaborates extensively with other researchers at Erasmus MC, including prominent scientists like Raaijmakers, Löwenberg, and Sanders, contributing to a robust research program in hematology and stem cell biology.