Christoph Fahlke

Prof. Christoph Fahlke is a Professor at the Institute for Biological Information Processes (IBI) within Forschungszentrum Jülich, leading the Molecular and Cellular Physiology (IBI-1) department. His research focuses on membrane transport mechanisms, synaptic transmission, and the pathophysiology of genetic disorders. Recent work emphasizes the role of glutamate transporters and CLC anion channels in neurological diseases.

Key research areas include:

• Mechanisms of ion transport in excitable cells
• Structure-function relationships of transporters like EAAT and ClC proteins
• Genetic mutations linked to neurodevelopmental disorders
• CLC channel modulation by fluoride and metabolic signals

His publications highlight collaborative approaches combining experimental and computational methods to study ion channels. Notable contributions include elucidating CLC-3's role in pain perception and EAAT-linked ataxias. Current work explores how transporter dysfunction impacts glial and neuronal physiology.

Prof. Fahlke's lab is part of the Helmholtz Association and collaborates widely, contributing to projects like the Peter Grünberg Institut. He has authored over 50 peer-reviewed articles and holds an ORCID ID: 0000-0001-8602-9952.