Alexander A. Mongin

Dr. Alexander Mongin is an Associate Professor in the Department of Neuroscience and Experimental Therapeutics at Albany Medical College. His research focuses on the roles of glial cells in neurological disorders, particularly stroke, Alzheimer's disease, and chronic neurodegeneration. He has received NIH funding for his work on excitotoxicity and ion transport mechanisms.

• Research areas: Glial cells, Stroke, Neurodegeneration, Excitotoxicity
• Grants: R01 NS035205, R21 NS052516

Dr. Mongin investigates how oxidative/nitrosative stress, glial cell swelling, and ion transport dysregulation contribute to neuronal damage. His work combines proteomics, biochemistry, and molecular biology approaches to identify therapeutic targets for neuroprotection.

His recent publications highlight mechanisms of glutamate toxicity, volume-regulated anion channels, and interactions between ion transporters and neurodegenerative processes. Key themes include:

• Pathological glutamate release
• Microglial activation in ischemia
• Oxidative protein modifications
• Clinical implications for stroke and glioblastoma

Dr. Mongin collaborates with clinician-scientists like neurosurgeon Dr. Yu-Hung Kuo and contributes to translational studies on brain tumors. His laboratory employs advanced techniques to analyze protein damage and develop neuroprotective strategies.