معرفی
Dr. Christian Bassi is a Lecturer in Cancer Biology and Group Leader at the University of Leeds, Faculty of Biological Sciences. He holds a PhD from the University of Toronto and has conducted postdoctoral research at the Campbell Family Institute for Breast Cancer Research and the Institute of Cancer Research, London. His research focuses on synthetic lethality and SUMOylation in cancer and neuronal differentiation.
Research Interests: His work centers on uncovering novel synthetic lethality interactions through CRISPR-based screening of the SUMO pathway, with therapeutic implications in cancer. He also investigates SUMO dynamics on chromatin during neuronal differentiation using advanced CUT&RUN technology. These interdisciplinary approaches bridge molecular oncology, epigenetics, and cell signaling.
Publication Trends: His recent research publications reflect a strong focus on tumor suppressor regulation, particularly PTEN, and its role in DNA damage response and cancer progression. The methodologies involve molecular genetics, cell-based assays, and high-throughput screening, indicating a translational research orientation with implications for targeted therapies.
- Scientific Awards:
- Cancer Research Institute Irvington Postdoctoral Fellowship Program
Advising and Grants: As a Group Leader, Dr. Bassi supervises research in his laboratory and leads independent projects. He is currently funded by the BBSRC IPA Tranche 2 (2024) for a project titled "Investigating the Role of SUMOylation in Neural Differentiation using CUT&RUN." This supports his innovative work at the intersection of chromatin biology and cellular differentiation.
Labs and Teams: Dr. Bassi leads his own research group at the University of Leeds, focusing on cancer biology and synthetic lethality. He previously contributed to research teams at the Campbell Family Institute and the Institute of Cancer Research, and has industry experience in assay development within a global pharmaceutical CDMO.
