Jo Morris

Jo Morris is a Professor of Molecular Genetics at the University of Birmingham, UK. Her career spans roles including Reader in Cancer Genetics (2013–present), Senior Lecturer (2010–2013), and Fellowships at King’s College London (2007–2010, 2003–2006). She leads research at the intersection of cancer genetics, DNA repair, and post-translational modifications.

• Doctor of Philosophy, University of London (1999)
• Bachelor of Arts, University of York (1995)

Research Focus: Morris's work explores how ubiquitin and SUMO pathways govern DNA damage responses, particularly in BRCA1-related breast and ovarian cancers. Her 2004 discovery of ubiquitin conjugation at double-strand breaks (108 citations) and subsequent studies on SUMO regulation of BRCA1 activity (Nature 2009) have shaped the field. Current projects include investigating SUMO activating enzymes and replication fork stability (grants from Cancer Research UK, Wellcome Trust, and Breast Cancer Campaign).

Article Trends: Over 15 recent publications emphasize DNA repair mechanisms, synthetic lethality, and post-translational modifications. Key subfields include BRCA1/53BP1 interactions, SUMO/deubiquitinating enzymes (POH1, USP50), SENP7 chromatin regulation, and implications for cancer therapy.

Scientific Awards:

• Breast Cancer Campaign Team of the Year 2009
• Birmingham Founders Award 2017
• SUMO in Double-Strand Break Repair Fellowship 2017

Grants & Collaborations:

• £1.4M Cancer Research UK grant (2015–2019) on ubiquitin in cancer
• £454.5K Breast Cancer Campaign Fellowship (2007–2011)
• Collaborations with Aga Gambus (MRC Fellow), CRUK Centre studentships, and international institutions (Queens University Belfast, University of Sydney).