معرفی
Charles Bayly-Jones is a Research Fellow in the Department of Biochemistry & Molecular Biology at Monash University. His work focuses on structural biology, protein dynamics, and their roles in immune systems and cancer. He leads the ARC-funded project 'New methods to capture protein dynamics of the TSC-mTOR signalling axis' (2024–2026) and contributed to the project 'Pleurotolysin: Developing a novel insecticide and nematicide for crop security' (2022).
His research interests include complement system proteins, membrane pore formation, and cancer-related signaling pathways. Recent work combines structural biology techniques like cryo-EM with computational methods to study protein interactions. Key contributions include elucidating the structure of the complement membrane attack complex and the metastatic factor P-Rex1.
Publications highlight advancements in understanding protein dynamics, drug targeting (e.g., cagrilintide), and therapeutic pathways in breast cancer. Grants and collaborations reflect interdisciplinary approaches to solving biological problems with applications in medicine and agriculture.
