Carolyn Sevier

Carolyn Sevier is a Professor in the Department of Molecular Medicine at Cornell University's College of Veterinary Medicine. She leads a research laboratory focused on redox signaling and protein homeostasis, with affiliations to the Biochemistry, Molecular, and Cell Biology (BMCB) and Biomedical & Biological Sciences (BBS) PhD programs. Dr. Sevier mentors graduate students and postdoctoral researchers, providing guidance through Cornell's structured academic pathways.

Research Focus

Her work spans redox regulation mechanisms in the endoplasmic reticulum, protein folding, and cellular stress responses. Key areas include:

• Thiol-based redox signaling pathways
• Chaperone-mediated protein homeostasis
• Interorganelle communication (ER-mitochondria)
• Oxidative stress adaptation
• Disulfide bond formation/reduction

Publication Trends

Recent articles (2016-2024) demonstrate a consistent focus on endoplasmic reticulum redox dynamics, chaperone functions (BiP/Hsp70), and stress response mechanisms. Work integrates yeast genetics, mammalian models, and biochemical approaches to explore fundamental cellular processes with implications for metabolic and degenerative diseases.

Academic Training

Dr. Sevier actively advises graduate students through Cornell's BMCB and BBS programs and recruits postdoctoral scholars. Her laboratory provides training in biochemical, genetic, and cell biological techniques for studying redox biology.