معرفی
Dr. Caroline Dewar is a Lecturer in Parasitology at the University of Lancaster's Faculty of Health and Medicine, within the Biomedical and Life Sciences department. Her research focuses on mitochondrial function in African trypanosomes, aiming to elucidate cellular mechanisms underlying mitochondrial quality control pathways and their implications for human diseases like neurodegenerative disorders and metabolic conditions. Her work also informs potential drug discovery for parasitic infections.
Dr. Dewar's laboratory investigates how trypanosomes, which cause devastating diseases in humans and cattle, manage mitochondrial dysfunction. By studying these evolutionarily unique eukaryotes, her research bridges fundamental biology and applied medicine. She actively supervises PhD and MSc students in trypanosome mitochondrial biology and can be contacted at c.dewar1@lancaster.ac.uk for inquiries.
Her professional activities include participation in international conferences (e.g., EMBO Workshop on Protein Quality Control, Swiss Trypanosomatid Meeting) and peer-review roles for journals like PLoS Neglected Tropical Diseases and Journal of The Royal Society Interface. She is affiliated with the Microbes, Pathogens and Immunity research group and has engaged in outreach activities such as the Furness STEM Show and UlverSTEM festivals.
Dr. Dewar's research outputs include studies on mitochondrial protein quality control, ATP synthase structure-function relationships, and the role of mitochondrial DNA in trypanosome biology. Her work highlights the unique adaptations of these parasites and their relevance to broader cellular biology and human health.
