معرفی
Prof. dr. Cor Calkhoven is a Professor at the Faculty of Medical Sciences, University of Groningen (UMCG), affiliated with the Molecular Oncology and Protein Homeostasis departments. His research focuses on gene regulation mechanisms, particularly translational control of mRNA, and its role in ageing, cancer, and metabolic diseases. He holds a PhD from the University of Groningen and has held postdoctoral fellowships at the Max Delbrück Center (Berlin) and the Leibniz Institute (Jena). His lab investigates the mTORC1 signaling pathway and its impact on healthspan and lifespan. Key research areas include C/EBPβ isoform regulation, metabolic reprogramming in cancer, and age-related disease mechanisms.
Education:
- Bachelor/Master’s in Biology and Chemistry, University of Groningen
- PhD in Molecular Biology, University of Groningen (1990s)
Research Interests: Translational control of gene expression, mRNA regulation in cancer, mechanisms of ageing and longevity, metabolic pathways in tumorigenesis, and the role of C/EBPβ isoforms in cellular differentiation.
Recent Articles: Focus on FTO demethylase oncogenic functions, TSC complex dual roles in cancer, and metabolic reprogramming via C/EBPβ-LIP.
Awards: None explicitly listed.
Grants/Advising: Supervised 7 students (names not specified). Active in grants related to ageing and cancer metabolism research.
Labs/Teams: Leads research at UMCG and ERIBA (European Research Institute for the Biology of Ageing), collaborating with institutions globally on metabolic and oncogenic mechanisms.
