Bindu Paul

Bindu Paul is an Associate Professor in the Department of Pharmacology and Molecular Sciences at the Johns Hopkins University School of Medicine, with joint appointments in Psychiatry and Neuroscience. Her research focuses on redox signaling mechanisms in neurodegenerative diseases, aging, and neuroprotection, particularly through hydrogen sulfide (H₂S) and nitric oxide (NO) pathways. She is affiliated with the Biochemistry, Cellular and Molecular Biology (BCMB), Neuroscience Training Program, and the Chemistry and Biology Interface Graduate Program.

Her research interests include cellular and molecular neuroscience, redox biology, neurodegenerative diseases such as Alzheimer’s and Huntington’s, traumatic brain injury, chronic fatigue syndrome, and long-term neurological effects of COVID-19. She investigates how post-translational modifications like persulfidation and nitrosylation regulate neuronal signaling and how their dysregulation contributes to disease pathophysiology. Her lab employs cell culture, mouse models, and patient samples to identify therapeutic targets within redox signaling networks.

Recent publications highlight her work on the Nrf2 pathway, biliverdin reductase, mitochondrial fission, and H₂S-based therapeutics. Her studies show that modulating redox networks offers neuroprotective benefits and may lead to novel treatments for neurodegeneration. She has published in top-tier journals including Science, Nature, PNAS, and Cell Metabolism, indicating a strong and ongoing research trajectory.

Scientific Awards:

• No specific awards listed in the provided text.

Dr. Paul has advised several graduate students and postdoctoral researchers, including J.I. Sbodio, S. Chakraborty, S.J. Tripathi, and C. Vasavda. Her work is supported by collaborations with prominent researchers such as Solomon H. Snyder and Andrew A. Pieper. She has not received mention of grants in the text, but her publication volume and journal impact suggest active funding. Her lab is located in the Hunterian Building at Johns Hopkins, with office in Room 307 and lab in Room 305.

She is actively involved in redox biology research, particularly in linking metabolic and signaling pathways in neurodegeneration. Her team explores how redox imbalance contributes to disease progression and how targeting these pathways can yield therapeutic interventions for conditions ranging from Alzheimer’s to long COVID.