معرفی
Prof. Bert Janssen is a structural biologist at Utrecht University, leading a research group focused on molecular mechanisms of intercellular signaling and adhesion in the nervous system. He is affiliated with the Bijvoet Centre for Biomolecular Research and employs techniques like protein crystallography, cryo-EM, and biophysical assays.
- Education
- MSc in Molecular Sciences, Wageningen University (2002)
- PhD in Structural Biology, Utrecht University (2007, cum laude)
His research bridges structural biochemistry and neurobiology, revealing how protein conformational changes drive cellular communication. Recent work includes structural insights into teneurin-3 dimerization and contactin-2 adhesion.
Publications highlight trends in neuronal signaling, protein architecture, and disease-related mechanisms (e.g., cancer, neurological disorders). He has secured major grants like the ERC Starting Grant (2015) and NWO VICI Grant (2023).
- Scientific Awards
- NWO VICI Grant (2023)
- ERC Starting Grant (2015)
- NWO VIDI Grant (2012)
- PUG Prize (2011)
- HFSP Fellowship (2009)
- HGK Westenbrink Prize (2008)
His lab investigates how structural dynamics of receptors, ligands, and adhesion proteins underpin tissue organization and disease pathology. Collaborations span institutions like the University of Oxford, where he conducted postdoctoral work on semaphorin-plexin signaling.
