Andrew Patrick Rice

Andrew Patrick Rice is a Professor in the Department of Molecular Virology & Microbiology at Baylor College of Medicine in Houston, Texas. He holds the Nancy Chang Endowed Professorship and is a member of the Dan L Duncan Comprehensive Cancer Center. His research focuses on gene expression regulation during viral infections, particularly HIV and influenza A.

• Ph.D., Brandeis University (1982)
• B.A., University of California, Santa Cruz (1973)
• Advanced training at Imperial Cancer Research Fund and University of Cambridge (1982)

Research Interests: Dr. Rice investigates how the HIV Tat protein interacts with cellular factors like P-TEFb (Cdk9/Cyclin T1) to regulate transcriptional elongation. His lab also explores influenza A NS1 protein interactions with PDZ domains and their role in virulence. Key areas include:

• Transcriptional regulation in HIV
• RNA polymerase II phosphorylation
• MicroRNA and lncRNA in viral replication
• PDZ protein associations in pathogenic viruses
• Cell cycle subversion by HIV
• Cyclin T1 induction during macrophage differentiation

Scientific Trends: His recent publications emphasize transcriptional elongation mechanisms in HIV, miRNA inhibition of viral replication, and PDZ-binding motifs in influenza virulence. Articles from 2003–2021 highlight cross-disciplinary insights into virology, molecular biology, and immunology.