
معرفی
Anant B. Parekh serves as Professor of Physiology and Director of the Centre for Integrative Physiology at the University of Oxford's Department of Physiology, Anatomy and Genetics (DPAG) within the Medical Sciences Division. He is also a Fellow of Merton College, Oxford, holding a continuous academic appointment since 1997.
His research focuses on intracellular calcium signalling mechanisms, particularly store-operated calcium channels (CRACs), calcium-dependent exocytosis in mast cells, and the physiological consequences of calcium dysregulation in disease. His laboratory investigates how plasma membrane channels interact with intracellular organelles like mitochondria to generate cellular responses.
Analysis of recent publications reveals consistent focus on CRAC channel pathophysiology across cardiovascular, dermatological, and immunological contexts, with increasing translational emphasis on therapeutic targeting of calcium signaling pathways since 2020.
- Fellow of the Royal Society (2019)
- Fellow of the Academy of Medical Sciences (2012)
- George Lindor Brown Prize (2012)
- India International Foundation Prize (2009)
- Wellcome Prize in Physiology (2002)
- Chair of Gordon Conference on Calcium Signalling (2017)
Parekh has secured major research fellowships including Lister Institute Senior Research Fellowship, Wellcome Trust Career Development Fellowship, and multiple college fellowships at Oxford. His laboratory maintains editorial leadership through positions on journals including Journal of Physiology and Cell Calcium. Current research directions focus on CRAC channel dysfunction in human disease with therapeutic development implications.
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