Michael A McCloskey

Dr. Michael A McCloskey is a retired Associate Professor at Iowa State University. He holds a B.S. in Plant Science from the University of California, Riverside (1974), and a Ph.D. in Biochemistry from the University of California, Davis (1979). His research focuses on membrane physiology across immune cells, neurons, and algae, particularly studying store-operated calcium entry (SOCE), potassium channels, and ABC-type transporters. Notable projects include investigating Pavlovian conditioning of allergic reactions via mast cell signaling, neuronal differentiation pathways in astrocyte-affected neural progenitors, and bicarbonate transport mechanisms in Chlamydomonas algae.

Key contributions include identifying CRAC channels' role in mast cell calcium influx and demonstrating NF-AT transcription factor activation in mast cells. His work also addresses biophysical problems like lipid mobility in glycosylation and complement attack complex membrane permeabilization. Dr. McCloskey has published extensively in journals like PLoS ONE, Journal of Neuroscience Research, and Journal of Biological Chemistry.

Publications from 2017 highlight interdisciplinary work in biomimetic wind energy systems, reflecting his broader interests in applying biological principles to engineering challenges. His research bridges immunology, neuroscience, and plant biology, emphasizing cellular signaling and membrane dynamics.