Amit Verma

Dr. Amit Verma is a Professor at Albert Einstein College of Medicine, leading the Amit Verma Laboratory focused on molecular mechanisms of blood cancers, particularly myelodysplastic syndromes (MDS) and leukemias. His research spans cellular signaling pathways, cancer stem cells, epigenomic analysis, and clinical trials to identify therapeutic targets.

Research Interests:
- Investigating inflammatory signaling pathways (e.g., IRAK4, TGF-β)
- Characterizing MDS/AML stem cells and their role in disease relapse
- Developing novel inhibitors (e.g., RVU120, HT-6184)
- Translating findings into clinical trials for anemia and treatment-resistant cancers
- Addressing healthcare disparities in minority populations

Recent Work Trends:
- Dominant focus on MDS pathogenesis and targeted therapies
- Integration of bioinformatics and epigenetic profiling for biomarker discovery
- Exploration of socioeconomic barriers to hematologic cancer care

Clinical Trials:
- Luspatercept efficacy in MDS patients
- Venetoclax/decitabine combinations in AML
- Emavusertib for FLT3-mutated AML

Labs/Teams:
The Amit Verma Lab collaborates with clinical teams at Montefiore Einstein Center for Cancer Care to translate discoveries into patient care, particularly through their MDS Center of Excellence clinic.