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Michael D EllisView profile

Professor

• Stroke Rehabilitation
• Motor Control
• Neurorehabilitation
• +3 more

Michael D Ellis is a Professor in the Department of Physical Therapy and Human Movement Sciences at the Feinberg School of Medicine, Northwestern University, where he conducts pioneering research at the intersection of neuroscience, biomechanics, and rehabilitation engineering to advance stroke recovery interventions. His research program focuses on quantifying motor impairments in chronic stroke survivors, particularly flexion synergy and loss of independent joint control in the upper extremity. He employs robotic systems (including the ACT3D platform), shear wave ultrasound elastography , and EMG-based pattern recognition to develop objective assessment tools and targeted therapies. A hallmark of his work is the investigation of progressive abduction loading as a mechanism to overcome gravity-induced discoordination, with significant contributions to understanding the biomechanical basis of elbow contracture and spasticity. Analysis of his 2019-2024 publications reveals three dominant research trajectories: (1) Development of mechatronic evaluation systems for inpatient stroke assessment with established test-retest reliability; (2) Cross-validation of biomechanical measures (e.g., ultrasound elastography as proxy for passive torque); (3) Neuroengineering applications using machine learning to decode movement intent for robotic rehabilitation. His work consistently bridges laboratory findings to clinical practice through quantitative metrics that differentiate impairment subtypes.

Susan DavisView profile

Professor

• Women's Health
• Endocrinology
• Menopause
• +5 more

Professor Susan Davis is a leading clinician researcher at Monash University , focusing on the role of sex hormones in women's health across the lifespan. She leads the Women’s Health Research Program and holds a Level 3 NHMRC Investigator Grant. Additionally, she serves as a Consultant Endocrinologist at Alfred Hospital Melbourne and Cabrini Medical Centre, with leadership roles in academic societies like the Australian Academy of Health and Medical Sciences. PhD in Molecular Biology, Monash University MBBS and FRACP in Endocrinology Her research spans from basic science to clinical trials, emphasizing non-reproductive effects of sex hormones in the brain (cognition, mood, sexual function), cardiovascular system , and bone/cartilage . She advocates for international best practices via co-authored guidelines and collaborations with regulatory bodies (FDA, EMA). Her work aligns with UN SDGs, particularly Education and Health . Recent publications highlight trends in menopause symptom management, hormone-cognition links, and testosterone's role in osteoarthritis. She has over 435 peer-reviewed articles and 475 total outputs. Scientific Awards : Novartis Award (1997) Glaxo Welcome International Diabetes Education Award (2000) Robert Greenblatt Award (2001) NAMS/Procter & Gamble Androgen Research Award (2002) ESA Mayne Pharma Bryan Hudson Clinical Endocrinology Award (2004) Medal of the Royal Australasian College of Physicians (2022) She contributes to national and international policy via advisory roles for the NHS Menopause Improvement Programme and Australian National Women’s Health Strategy. Her clinical advocacy includes hormone therapy guidelines and industry partnerships. Professor Davis actively supervises PhD students and leads major projects like the ETHEL Study (testosterone therapy for heart failure) and MenoPROMPT (menopause care programs), with funding from the NHMRC, MRFF, and Heart Foundation.

Michael J. JoynerView profile

Professor

• Blood Flow Regulation
• Exercise Physiology
• Blood Pressure Regulation
• +7 more

Michael J. Joyner, M.D., is a Professor of Anesthesiology at Mayo Clinic, with joint appointments in Physiology & Biomedical Engineering. He leads research into human physiological responses to stress, including exercise, hypoxia, and cardiovascular challenges. His work focuses on blood flow regulation, glucose metabolism, and integrative physiology in health and disease. Education: MD from University of Arizona, BS in Nutrition and Food Science (University of Arizona). Professional Roles: Consultant in Anesthesiology and Physiology, Principal Investigator of major NIH-funded studies. Research Interests: Blood flow dynamics during exercise Cardiovascular and metabolic responses to stress Convalescent plasma therapies for infectious diseases Elite athlete physiology and performance limits Sex differences in health and disease Recent publications emphasize sex-based disparities in sports performance, field-based health research in athletes, and mechanisms of glucose regulation. His work bridges clinical and basic science to inform therapeutic targets. Awards: Includes the Walter B. Cannon Lecture (2013), Edward F. Adolph Distinguished Lecture (2011), and D.Sc. (Honoris Causa) from McMaster University (2018). Labs/Teams: Active in Mayo Clinic's Anesthesiology, Physiology, and Regenerative Biotherapeutics research programs. Collaborations span global institutions.

Kenton R. KaufmanView profile

Professor

• Human Locomotion
• Biomechanics
• Prosthetics and Orthotics
• +4 more

Kenton R. Kaufman, Ph.D., is a Professor of Biomedical Engineering and Orthopedics at Mayo Clinic, holding the W. Hall Wendel Jr. Musculoskeletal Research Professorship. He leads the Motion Analysis Laboratory, focusing on human locomotion, prosthetics, and musculoskeletal rehabilitation. His academic appointments span the Departments of Orthopedic Surgery, Physiology & Biomedical Engineering. He earned his Ph.D. in Biomechanical Engineering from North Dakota State University and completed postdoctoral training at Mayo Clinic. Research interests include advanced prosthetics, gait analysis, neuromuscular disorders, and clinical biomechanics. He has led projects funded by the National Science Foundation, Department of Defense, and NIH, including work on robotic ankle prosthetics and training methods for wounded warriors. Over 372 publications reflect expertise in biomechanics, musculoskeletal rehabilitation, and clinical engineering. Honors include the Borelli Award (2013), John Insall Award (2012), and Distinguished Engineer recognition (2008). His clinical practice integrates 3D motion analysis, electromyography, and plantar-pressure measurement. He directs research in Mayo's Department of Orthopedic Surgery and collaborates internationally on musculoskeletal and rehabilitation sciences.

David R. LindenView profile

Associate Professor

• Gastroenterology
• Neuroscience
• Physiology
• +3 more

David R. Linden, PhD, is an Associate Professor in the Department of Physiology & Biomedical Engineering at Mayo Clinic, Rochester, Minnesota. His primary affiliation is with Mayo Clinic's research division, holding an Administrative Appointment as Associate Consultant II-Research. He leads multiple NIH-funded projects focusing on enteric nervous system biology, gastrointestinal motility disorders, and neuroregenerative strategies. Dr. Linden’s research integrates molecular biology, animal models, and clinical insights to understand gut-brain interactions and develop therapies for conditions like gastroparesis and enteric neuropathies. Education includes a PhD in Neuroscience from the University of Minnesota and BS in Biology from the University of Wisconsin-Stevens Point. Postdoctoral training included roles at the University of Vermont (Anatomy & Neurobiology) and University of Minnesota (Psychiatry). Research Focus: Key areas include enteric glia-neuron signaling, intestinal motility mechanisms, microbiota-gut interactions, and regenerative therapies for enteric neuropathies. His work emphasizes translational studies using murine models and patient-derived samples. Grants & Projects: Active grants include NIH-funded studies on intrinsic afferent neurons, computational autonomic neurobiology, and polyp growth signaling. Recent projects explore adeno-associated virus therapies for diabetic gastroparesis and circadian rhythm influences on gut transit. Affiliations: Director of the Enteric Neuroscience Program and member of Mayo’s Center for Cell Signaling in Gastroenterology and Center for Multiple Sclerosis & Autoimmune Neurology.

Christina A PacakView profile

Associate Professor

• Neurology
• Genetics
• Mechanisms of Cancer
• +13 more

Christina A. Pacak is an Associate Professor in the Department of Neurology at the University of Minnesota. Her research is centered on the genetics and mechanisms of cancer and rare neuromuscular disorders, particularly Barth syndrome and Cockayne syndrome. She leads multiple externally funded research projects with the NIH, FDA, and Sarepta Therapeutics, focusing on gene therapy, mitochondrial dysfunction, and cardiac and skeletal muscle pathologies. Her research interests include: Gene therapy using adeno-associated virus (AAV) vectors CRISPR/Cas9 genome editing for dilated cardiomyopathy Induced pluripotent stem cell (iPSC)-derived cardiomyocyte models Mechanisms of mitochondrial dysfunction in Barth syndrome Extracellular matrix remodeling in cardiac fibroblasts Behavioral assessment in aging and neurodegenerative models Her recent publications (2024–2025) demonstrate a strong focus on translational applications, including AAV vector optimization for CNS targeting, rescue of mitochondrial defects, and development of clinical models for rare diseases. These works span disciplines such as genetics, neurology, molecular biology, and biomedical engineering, reflecting a highly interdisciplinary approach. Her scientific contributions are supported by major grants, including: National Institutes of Health (NIH) – Mechanisms and Treatment of Cardiac and Skeletal Muscular Dysfunction in Barth Syndrome DHHS FDA – Optimized Production of AAV Vectors for Cockayne Syndrome University of Florida / Sarepta Therapeutics – Canine iPSC-Cardiomyocyte Studies and CRISPR gene therapy development She collaborates extensively with leading researchers in neuromuscular disease and gene therapy. While specific advisees are not listed, her role as Principal Investigator indicates active mentorship of graduate students and postdoctoral researchers. She also contributes to open science through public datasets on figshare.

• Parkinson's disease
• Deep brain stimulation
• Movement disorders
• +5 more

Michael S. Okun is a prominent Professor and Chair of the Department of Neurology at the University of Florida College of Medicine, where he directs the Parkinson's Foundation Center of Excellence. He is internationally recognized as a leading expert in Parkinson's disease and movement disorders with over 986 publications and an h-index of 92. Dr. Okun's research spans multiple critical domains in movement disorders: Diagnosis and clinical management of Parkinson's disease Deep brain stimulation mechanisms, targets, and outcomes Comparative effectiveness of STN versus GPi stimulation Motor and non-motor symptom progression Cognitive and mood aspects of movement disorders The emerging 'Parkinson pandemic' and global disease burden Analysis of Dr. Okun's extensive publication record reveals a career dedicated to bridging basic neuroscience with clinical application. His early work established foundational knowledge about how subthalamic nucleus stimulation changes basal ganglia firing patterns. More recent work addresses the growing public health implications of Parkinson's disease prevalence, with his highly cited 2018 paper on the 'Parkinson pandemic' predicting potential cases exceeding 17 million due to increasing longevity, declining smoking rates, and industrialization. Dr. Okun has made significant contributions to clinical guidelines and consensus statements: Lead author of the influential 2020 JAMA review on Parkinson's disease diagnosis and treatment (over 2,000 citations) Principal investigator for the landmark COMPARE trial comparing cognitive outcomes of different DBS targets Contributor to the 2011 expert consensus on deep brain stimulation for Parkinson disease Developer of innovative rehabilitation approaches like EMST for swallowing disorders As an academic leader, Dr. Okun mentors numerous researchers and clinicians through interdisciplinary collaborations spanning neurology, neurosurgery, psychiatry, and rehabilitation medicine. His work continues to shape global standards for Parkinson's disease management and has directly impacted treatment protocols for thousands of patients worldwide.

Alejandro Pablo AdamView profile

Associate Professor

• Inflammatory Responses
• Vascular Permeability
• Endothelial Cell Biology
• +6 more

Alejandro Pablo Adam is an Associate Professor in the Department of Molecular and Cellular Physiology at Albany Medical College. His research focuses on the pathophysiology of disproportionate inflammatory responses, emphasizing vascular permeability and organ dysfunction in conditions like sepsis, rosacea, and uveitis. He leads a lab dedicated to identifying therapeutic targets for excessive inflammation and tissue damage. Education: PhD, University of Buenos Aires (2007) BS/MS, University of Buenos Aires (1999) Dr. Adam's research explores both acute and sustained mechanisms of vascular leakage caused by cytokines such as IL-6 and TNF-α. Key areas include STAT3 signaling in endothelial cells, epigenetic responses in shock, and the role of adherens junctions in inflammation. His work bridges molecular studies with translational clinical trials, particularly for ocular rosacea. His recent publications and ongoing studies highlight advancements in understanding cytokine-driven vascular dysfunction, innate immunity in chronic inflammation, and novel anti-inflammatory therapeutics. These align with his lab's mission to translate findings into treatments. Scientific Awards & Funding: NIGMS R35 Award (2024) for endothelial signaling research NIH/NIGMS grants supporting vascular leakage and angiogenesis studies Dr. Adam's lab employs cutting-edge techniques like Airyscan and STED microscopy to investigate endothelial junction dynamics. Collaborative projects span pre-eclampsia, chorioretinal diseases, and sepsis models, with mentorship provided to PhD students like Shuhan Lu and postdoctoral fellows.

• Musculoskeletal Disorders
• Sports Medicine
• Pain Research
• +7 more

Iben Axén leads the Musculoskeletal Disorders and Sports Medicine Research Group at Karolinska Institutet's Institute of Environmental Medicine. Her research program focuses on musculoskeletal pain (particularly neck and back disorders), sports injuries, and their intersections with mental health and workplace factors. She maintains extensive international collaborations across Scandinavia, with significant contributions to chiropractic research and evidence-based practice development. Her research interests span musculoskeletal pain mechanisms , sports injury prevention (particularly in youth football and handball), post-COVID conditions , and workplace interventions for mental health disorders. Key methodologies include randomized controlled trials, longitudinal cohort studies, and qualitative investigations of rehabilitation processes. Recent work explores ethical challenges in workplace mental health interventions, biomechanical aspects of spinal manipulation, and multidimensional impacts of post-COVID conditions. Analysis of recent publications reveals strong emphasis on translational research bridging clinical practice and population health. Her team frequently examines how psychological factors modify physical pain outcomes, investigates biomarkers like heart rate variability in pain conditions, and develops instruments for patient selection in maintenance care programs. International collaborations with Norwegian and Danish researchers feature prominently in her work on chiropractic maintenance care. Her team actively contributes to methodological advancements in pain research through innovative data collection techniques including SMS-based longitudinal monitoring and development of clinical prediction tools. Current projects address critical gaps in understanding post-viral syndromes, sports injury prevention in adolescent athletes, and optimizing workplace rehabilitation for mental health conditions.

Lars EideView profile

Professor

• Mitochondrial Biology
• DNA Repair
• Molecular Genetics
• +3 more

Lars Eide is a Professor and Research Leader at the Faculty of Medicine, University of Oslo (UiO) and Oslo University Hospital (OUS) . His work focuses on mitochondrial DNA (mtDNA) repair, oxidative damage, and its role in neurodegenerative and metabolic diseases. He leads the Mitogroup research team and manages the PhD course "Biomarkers for Clinical Research". Research Interests Mitochondrial DNA modifications and repair mechanisms Interplay between mitochondrial function and mtDNA dynamics Metabolic disorders (e.g., Maple Syrup Urine Disease) Neurodegenerative diseases (e.g., Huntington's, Leigh Syndrome) Lipid metabolism and atherosclerosis Cancer metabolism (e.g., pancreatic and prostate cancer) Recent Article Trends include studies on branched-chain fatty acids in diabetes, mtDNA repair in neurogenesis, and metabolomic profiling for cancer biomarkers. His work spans biochemistry , genetics , and clinical applications , with collaborations across institutions like UiO, OUS, and NTNU. Projects include "Functional effects of mitochondrial heteroplasmy" and "Metabolic causes of mitochondrial dysfunction." He holds a Dr. Scient in Mathematics/Natural Sciences from UiO (1997) and a Civil Engineering in Chemistry (Trondheim, 1992).

Marte Charlotte Dobbertin GramView profile

Researcher

• Injury prevention
• Sports injuries
• Overuse injuries
• +5 more

Marte Charlotte Dobbertin Gram is a PhD Research Fellow at the Norwegian School of Sport Sciences (NIH) , Department of Sports Medicine. She combines academic research with clinical practice as a physiotherapist for the Norwegian Gymnastics Federation’s national rhythmic gymnastics team. Education: Bachelor’s in Physiotherapy (NTNU/HiST, 2011-2014), Master’s in Sports Physiotherapy (NIH, 2019) Academic Role: PhD Research Fellow (NIH, ongoing) Clinical Role: Physiotherapist for Norwegian rhythmic gymnastics national team Research Focus: Injury prevention and women’s health in aesthetic sports (rhythmic gymnastics, ballet, dance), with emphasis on urinary incontinence, musculoskeletal disorders, and risk factors. Her work includes cluster-randomized trials and epidemiological studies. Recent Publications address pelvic floor health, injury prevention programs, menstrual cycle communication, and preseason injury patterns in elite female athletes. Teaching: Covers topics such as musculoskeletal disorders, flexibility training, and data handling in sensitive contexts for the Bachelor’s program in Exercise, Health, and Performance.

• Cardiovascular Medicine
• Neuroscience
• Medical Research
• +3 more

Alexey Larionov is a Senior Researcher at the Faculty of Science and Medicine, University of Fribourg, Switzerland. His primary affiliation is within the Medicine Section, where he focuses on advanced biomedical research. His work spans cardiovascular medicine, cellular biology, and infectious diseases, with a particular emphasis on endothelial dysfunction, microglia activity, and renal physiology. Larionov’s research integrates experimental and clinical approaches to address mechanisms underlying diseases such as diabetic kidney disease, SARS-CoV-2 neuropathology, and vascular pathologies. He holds a prominent role in anatomical and medical education, having contributed to innovative teaching methods during the pandemic. His expertise includes anatomical variations impacting clinical conditions like piriformis syndrome and the neuroinflammatory effects of viral infections. Larionov’s studies also explore therapeutic targets for cardiovascular and renal disorders, leveraging molecular mechanisms such as mTOR signaling and cathepsin enzyme activity. Though no formal academic awards are listed, his prolific publication record reflects sustained contributions to medical science. He is reachable at alexey.larionov@unifr.ch and maintains an ORCID profile (0000-0001-6902-8878).

Hong ChenView profile

Associate Professor

• Vascular Biology
• Atherosclerosis
• Lymphatic System
• +5 more

Hong Chen is a Principal Investigator at Boston Children's Hospital and an Associate Professor of Surgery at Harvard Medical School . Their work bridges vascular biology, computational methods, and metabolic disease research, with a focus on atherosclerosis, diabetes, and lymphatic system regulation. Harvard Medical School, Department of Surgery Boston Children's Hospital, Chen Lab Research spans endothelial cell signaling , single-cell RNA sequencing , and metabolite-mediated communication . Key areas include: FOXM1/Dab2 pathways in diabetic wound healing Epsin proteins in atherosclerosis and lipid metabolism Development of MEBOCOST algorithm for metabolite-CRC detection CXCL12/CXCR4 in neuro-lymphatic communication VEGFR3 and caveolae inhibition in lymphatic fate determination Recent publications highlight machine learning applications for cell identity genes, metabolite signaling in adipose tissue, and transcriptional regulators in cardiovascular disease. No explicit scientific awards or student advisement details were found in the provided text.

• Geriatric Physical Therapy
• Muscle Fat Infiltration
• Mobility Assessment
• +6 more

Dr. Addison Odessa serves as an Associate Professor in the Department of Physical Therapy and Rehabilitation Science at the University of Maryland School of Medicine, where she also holds the Director for Research Affairs administrative role. With dual doctoral qualifications (DPT and PhD) from the University of Utah, she completed postdoctoral training at the University of Maryland and the Baltimore VA Medical Center, establishing herself as a Research Health Scientist and GRECC Investigator for the VA Maryland Health Care System. Education: DPT and PhD (University of Utah) Postdoctoral Fellowship: University of Maryland School of Medicine Special Fellowship: Geriatrics (Baltimore VA Medical Center) Dr. Addison's research focuses on muscle fat infiltration , mobility dysfunction , and balance assessment in aging populations, particularly older veterans. Her work examines how hip abductor muscle composition affects postural control, and she investigates lifestyle interventions (diet/exercise) to mitigate age-related decline. Funded by the NIH , VA , and Foundation for Physical Therapy, she co-leads the NIH Pepper Center's Research Education Core. Recent publications analyze gait variability , respiratory-muscle interactions , and telehealth balance assessment . Her team's work spans muscle imaging , inflammatory responses , and community-based interventions like VETS AND VEGGIES, while maintaining rigorous methodological focus on ultrasound measurement reliability and ImageJ analysis discrepancies . NIH Pepper Center co-leader VA Maryland Health Care System researcher Gerofit program longitudinal studies GLP-1 therapy and mobility research Dr. Addison's scientific contributions include evaluating neuromuscular activation in older adults, exploring muscle-bone crosstalk , and investigating prebiotic effects on aging cognition . Her clinical work addresses disordered eating in older adults and develops peer-led diet/exercise programs for veterans with dysmobility.

• Cancer Biology
• Endothelial Cell Biology
• Chronic Disease Research
• +3 more

Dr Leonid Nikitenko is a Lecturer in Biomedical Sciences at Hull York Medical School, University of Hull. His interdisciplinary research bridges biology, medicine, and computer science, focusing on endothelial cell roles in chronic diseases including cancer, idiopathic pulmonary fibrosis (IPF), cardiovascular disorders, and lymphoedema. He employs platform technologies like proteomics and genomics for early cancer detection, with a dedicated website ( www.endothelial-cell.com ) showcasing his work. Former lab alumni now hold positions at top institutions including Oxford, Warwick, and London-based hospitals and biotech companies. His research spans: Endothelial cell reprogramming in disease states Angiogenesis mechanisms in cancer and fibrosis Proteomic and genomic profiling for diagnostic signatures Coagulation-cancer axis in tumor vascularization GPCR signaling in vascular pathologies Recent publications highlight his work in: Quantitative proteomics of CLR interactome (2024) MAPK phosphorylation dynamics in endothelial cells (2023-2024) Single-cell RNA sequencing of aging lung endothelium in IPF (2022) Mechanistic studies on anticoagulant therapies in oncology (2019) Dr Nikitenko's work at the Hull Molecular Imaging Centre contributes to understanding vascular biology across multiple pathologies, with translational applications in diagnostic development and therapeutic targeting.