Michael S. Okun
Professor · Parkinson's disease
Schloss Dagstuhl - Leibniz Center for InformaticsAbout
Michael S. Okun is a prominent Professor and Chair of the Department of Neurology at the University of Florida College of Medicine, where he directs the Parkinson's Foundation Center of Excellence. He is internationally recognized as a leading expert in Parkinson's disease and movement disorders with over 986 publications and an h-index of 92.
Dr. Okun's research spans multiple critical domains in movement disorders:
- Diagnosis and clinical management of Parkinson's disease
- Deep brain stimulation mechanisms, targets, and outcomes
- Comparative effectiveness of STN versus GPi stimulation
- Motor and non-motor symptom progression
- Cognitive and mood aspects of movement disorders
- The emerging 'Parkinson pandemic' and global disease burden
Analysis of Dr. Okun's extensive publication record reveals a career dedicated to bridging basic neuroscience with clinical application. His early work established foundational knowledge about how subthalamic nucleus stimulation changes basal ganglia firing patterns. More recent work addresses the growing public health implications of Parkinson's disease prevalence, with his highly cited 2018 paper on the 'Parkinson pandemic' predicting potential cases exceeding 17 million due to increasing longevity, declining smoking rates, and industrialization.
Dr. Okun has made significant contributions to clinical guidelines and consensus statements:
- Lead author of the influential 2020 JAMA review on Parkinson's disease diagnosis and treatment (over 2,000 citations)
- Principal investigator for the landmark COMPARE trial comparing cognitive outcomes of different DBS targets
- Contributor to the 2011 expert consensus on deep brain stimulation for Parkinson disease
- Developer of innovative rehabilitation approaches like EMST for swallowing disorders
As an academic leader, Dr. Okun mentors numerous researchers and clinicians through interdisciplinary collaborations spanning neurology, neurosurgery, psychiatry, and rehabilitation medicine. His work continues to shape global standards for Parkinson's disease management and has directly impacted treatment protocols for thousands of patients worldwide.
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