Hong Chen

Hong Chen is a Principal Investigator at Boston Children's Hospital and an Associate Professor of Surgery at Harvard Medical School. Their work bridges vascular biology, computational methods, and metabolic disease research, with a focus on atherosclerosis, diabetes, and lymphatic system regulation.

• Harvard Medical School, Department of Surgery
• Boston Children's Hospital, Chen Lab

Research spans endothelial cell signaling, single-cell RNA sequencing, and metabolite-mediated communication. Key areas include:

• FOXM1/Dab2 pathways in diabetic wound healing
• Epsin proteins in atherosclerosis and lipid metabolism
• Development of MEBOCOST algorithm for metabolite-CRC detection
• CXCL12/CXCR4 in neuro-lymphatic communication
• VEGFR3 and caveolae inhibition in lymphatic fate determination

Recent publications highlight machine learning applications for cell identity genes, metabolite signaling in adipose tissue, and transcriptional regulators in cardiovascular disease. No explicit scientific awards or student advisement details were found in the provided text.