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James B Bliskaمشاهده پروفایل

استاد

Dartmouth CollegeUnited States

James B. Bliska is a Professor of Microbiology and Immunology at the Geisel School of Medicine at Dartmouth, and Distinguished Professor serving as Senior Lead Faculty Member of the Dartmouth Personalized Treatments for Cystic Fibrosis (CF) Cluster. He holds a BS in Bacteriology from the University of Wisconsin-Madison (1983) and a PhD in Molecular Biology from the University of California-Berkeley (1988). His research focuses on bacterial effectors' interactions with host leukocytes, particularly in pathogenesis and immune defense mechanisms. Key areas include Yersinia, Pseudomonas, and Burkholderia pathogenesis, inflammasome regulation, and Cystic Fibrosis-related lung infections. Dr. Bliska's leadership in the CF Cluster aims to advance translational research and training in CF and lung diseases. He has mentored 15 graduate students and 7 postdoctoral fellows, emphasizing diversity in STEM. His lab explores type III and VI secretion systems, effector-triggered immunity, and synthetic immunology approaches to combat lung infections. Education: BS, Bacteriology, University of Wisconsin-Madison (1983) PhD, Molecular Biology, University of California-Berkeley (1988) Postdoctoral Training, Stanford University (1993) Leadership: Senior Lead Faculty Member, CF Cluster Former Director, Center for Infectious Diseases (Stony Brook University) Research Themes: Yersinia effector-pyrin interactions Pseudomonas and Burkholderia CF lung infections Inflammasome activation and immune evasion His lab combines molecular, cellular, and immunological approaches to understand host-pathogen interactions. Recent work highlights synthetic immunology strategies and the role of bacterial effectors in immune regulation.

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Arne Rietschمشاهده پروفایل

دانشیار

Case Western Reserve UniversityUnited States

Arne Rietsch, PhD is an Associate Professor in the Department of Molecular Biology and Microbiology at Case Western Reserve University School of Medicine. He also serves as the Associate Director of the Medical Scientist Training Program at the School of Medicine. His research focuses on bacterial pathogenesis, particularly studying how Pseudomonas aeruginosa causes disease through its type III secretion system. Dr. Rietsch's laboratory investigates three main aspects of the type III secretion system (T3SS): translocator protein secretion, the control mechanisms that prevent effector secretion prior to cell contact (involving PcrG/PcrV and the PopN complex), and the mechanism by which cell contact triggers effector secretion. His work has revealed that translocation of effector proteins can be feedback inhibited by the type III effector ExoS. His research spans bacterial pathogenesis, molecular microbiology, host-pathogen interactions, and bacterial secretion systems, with important implications for treating infections caused by this opportunistic pathogen. Dr. Rietsch's recent publications (2022-2025) demonstrate continued research productivity across multiple areas including bacterial pathogenesis, immunology, and regenerative medicine. His work shows consistent focus on Pseudomonas aeruginosa mechanisms while expanding into related fields like STING pathway regulation and liver fibrosis. Small molecule induced STING degradation facilitated by the HECT ligase HERC4 (2024) The transcription factor ZNF469 regulates collagen production in liver fibrosis (2025) A biofilm-tropic Pseudomonas aeruginosa bacteriophage uses the exopolysaccharide Psl as receptor (2025) NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity (2023) PopB-PcrV Interactions Are Essential for Pore Formation in the Pseudomonas aeruginosa Type III Secretion System Translocon (2022) As Associate Director of the Medical Scientist Training Program, Dr. Rietsch plays a significant role in training the next generation of physician-scientists. His laboratory provides research opportunities for graduate students and postdoctoral fellows interested in bacterial pathogenesis and molecular microbiology, with collaborations particularly strong with Dr. Eric Pearlman on ocular infections. The Rietsch lab combines genetic, biochemical, and cell biological approaches to understand how P. aeruginosa interacts with host cells at the molecular level. Their work addresses important questions in infectious disease research with relevance to public health, particularly for immunocompromised patients, burn victims, and those with cystic fibrosis.

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Mikael Elofssonمشاهده پروفایل

استاد

Umea UniversitySweden

Mikael Elofsson is a Professor and Dean of the Faculty of Science and Technology at Umeå University. He holds a PhD from the Lund Institute of Technology (1996) and completed postdoctoral research at Yale University. His research focuses on antiviral and antibacterial compounds, particularly targeting viral entry mechanisms and bacterial virulence systems. Key projects include developing glycoconjugates and small molecules against adenoviruses, coxsackieviruses, and Pseudomonas aeruginosa. He leads the Mikael Elofsson lab, exploring chemical probes for ADP-ribosyltransferases and epigenetic signaling. Notable collaborations include work with AstraZeneca on antiviral drug discovery. Education: PhD in Organic Chemistry (1996, Lund Institute of Technology); Postdoc at Yale University (1996–1999) Affiliations: Department of Chemistry, Faculty of Science and Technology, Umeå University Research interests span antiviral drug development, bacterial virulence inhibition, and epigenetic modifiers. His lab’s work on salicylidene acylhydrazides led to the FDA-approved drug Kyprolis (Carfilzomib). Current projects include inhibitors for type III secretion systems and ADP-ribosyltransferases, with applications in infectious diseases and cancer. Publications highlight advancements in antiviral small molecules (e.g., benzavir-2), trivalent sialic acid inhibitors for adenoviruses, and structure-based design of PARP inhibitors. His work bridges chemistry and biology, with a focus on translational medicine.

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Michael Laiosaمشاهده پروفایل

دانشیار

University of Wisconsin-MilwaukeeUnited States

Dr. Michael Laiosa is an Associate Professor and Faculty Chair at the University of Wisconsin-Milwaukee , affiliated with the College of Health Sciences and Department of Environmental Health Sciences . He holds a PhD in Microbiology and Immunology from SUNY Upstate Medical University and a BS in Biochemistry from SUNY at Geneseo. Education : PhD, Microbiology and Immunology (SUNY Upstate Medical University); BS, Biochemistry (SUNY at Geneseo) Research Interests focus on the impact of developmental exposure to environmental contaminants like dioxins on hematopoietic stem cells and long-term immune system health. His work bridges mechanistic toxicology with public health, particularly addressing disparities in urban communities. Teaching : Courses include PH 703 (Environmental Health Sciences), PH 819 (Social and Environmental Justice), and PH 821 (Advanced Survey of Environmental and Occupational Health).

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Richard Haywardمشاهده پروفایل

دانشیار

University of CambridgeUnited Kingdom

Dr Richard Hayward serves as a University Associate Professor in the Microbiology Division of the Department of Pathology at the University of Cambridge and holds the position of Director of Studies and Fellow in Medical Sciences at Trinity College. His research focuses on the molecular mechanisms of bacterial infections, particularly obligate intracellular pathogens. His work centers on Chlamydia trachomatis , the leading bacterial cause of sexually transmitted diseases globally and trachoma-induced blindness in developing nations. Key research areas include: Intracellular biology of pathogen-host interactions Type III secretion system (T3SS) effector proteins Inclusion biogenesis and membrane compartment reprogramming Structural mimicry of eukaryotic functions by bacterial effectors Cellular processes subverted during infection (cytoskeletal dynamics, intracellular trafficking) Hayward employs biochemical, cell biology, and advanced bio-imaging approaches alongside emerging genetic techniques to investigate these processes. His laboratory operates within the Microbiology and Parasitology Division, with active research on Chlamydia 's virulence mechanisms involving >50 putative effector proteins. No scientific awards were explicitly documented in the source materials. As Director of Studies at Trinity College, Hayward supervises PhD students and contributes to undergraduate medical sciences education. His group maintains active research collaborations within the Department of Pathology's specialized facilities including the Pathogen Cryo-Imaging Facility (PaCIFiC). Current research priorities include deciphering effector protein functions and identifying novel therapeutic targets against neglected tropical diseases. The Hayward Group operates within the Department of Pathology's Microbiology and Parasitology Division, utilizing advanced imaging and genomic facilities. Current research focuses on characterizing anonymous chlamydial proteins (comprising ~35% of the genome with no homology to known proteins) and their role in pathogenesis.

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A. Wali Karzaiمشاهده پروفایل

استاد

Stony Brook UniversityUnited States

Professor A. Wali Karzai is a leading faculty member at Stony Brook University , where he serves as Professor and Chair of the Department of Biochemistry and Cell Biology . A 2003 Pew Scholar in the Biomedical Sciences, he heads the Karzai Lab, which investigates the molecular mechanisms governing protein and RNA homeostasis, ribosome rescue, and post-transcriptional regulation in bacteria. Research Interests: Post-transcriptional regulation of gene expression Protein homeostasis and adaptor-guided proteolysis Quality control of nascent polypeptide synthesis Quality control of mRNA decoding and decay Role of tmRNA/SmpB system in bacterial virulence His group combines classical biochemistry, structural biology, molecular genetics, functional genomics, and bioinformatics to dissect the function of RNA–protein complexes that orchestrate gene expression and protein quality control. Current projects focus on the tmRNA-mediated trans-translation process, nonstop mRNA decay, Lon protease–directed degradation, and the physiological significance of these pathways in pathogenic bacteria such as Yersinia and Francisella . Scientific Awards: Pew Scholar in the Biomedical Sciences (2003) Advising & Mentorship: The Karzai Lab has trained numerous graduate students and postdoctoral researchers. Current lab members include postdocs Thiago Rodrigues, PhD, Melanie Cragan, Javon Lo, and Nina Cheng. Alumni have secured independent positions in academia and industry. The group is actively recruiting graduate students and postdocs interested in RNA biology, proteostasis, and bacterial pathogenesis. Lab & Collaborations: The laboratory is housed within the Centers for Molecular Medicine at Stony Brook University and is equipped for high-resolution structural studies, high-throughput genetics, and quantitative biochemistry. Collaborative projects span microbiology, structural biology, and infectious disease programs across campus and with external partners.

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Debra L Miltonمشاهده پروفایل

استاد

Umea UniversitySweden

Debra L Milton is a Professor in the Department of Molecular Biology at Umeå University, where she leads a research group focused on infection biology. She also serves as the national director of the National Doctoral Programme in Infections and Antibiotics (NDPIA), a significant player in the national infection biology arena. Education: PhD from University of Alabama (1986) Postdoctoral research at Howard Hughes Medical Institute, Salt Lake City, Utah (1986-1989) Postdoctoral research at Umeå University (1990) Dr. Milton's research primarily focuses on the virulence and survival mechanisms of the fish pathogen Vibrio anguillarum . Her group investigates how this bacterium communicates within its population to coordinate complex activities such as biofilm formation, colonization of host tissues, and protein secretion via the type VI secretion system. A key aspect of her work examines how bacteria evade phagocytic capacity of epithelial cells to colonize fish skin surfaces. In collaboration with researchers at Troy University, Alabama, she also investigates the microbial safety of using pureed whole foods for tube feeding. Analysis of Dr. Milton's publication record reveals a strong focus on bacterial communication systems, particularly quorum sensing in Vibrio species. Her work spans molecular mechanisms of virulence, biofilm formation, and host-pathogen interactions in aquatic environments. The research has significant implications for understanding fish diseases and developing therapeutics for the fish farming industry. Contact Information: Email: debra.l.milton@umu.se Phone: +46 90 785 08 15 Location: 6K and 6L, Hospital area, Umeå University, 901 87 Umeå As national director of NDPIA, Dr. Milton plays a key role in shaping doctoral education in infection biology across Sweden. Her research group continues to investigate fundamental mechanisms of bacterial pathogenesis with applications to aquaculture and food safety. Her laboratory focuses specifically on how Vibrio anguillarum constitutes part of the normal microflora of the aquatic environment but can cause vibriosis, a terminal hemorrhagic septicaemia, when fish health is compromised. Understanding these mechanisms aims to aid in the development of therapeutics to prevent disease in the fish farming industry.

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Sara Paisمشاهده پروفایل

پژوهشگر

University of TübingenGermany

Sara Pais is a researcher affiliated with the Faculty of Mathematics and Natural Sciences at an unspecified university, specializing in the Department of Cellular and Molecular Microbiology . Her work focuses on molecular mechanisms of bacterial pathogenesis through Type III and Type IV secretion systems, particularly the targeting and insertion of effector proteins into host cell membranes. General Research Areas : Bacterial Pathogenesis, Host-Pathogen Interactions, Type III Secretion Systems, Type IV Secretion Systems, Molecular Microbiology, Membrane Protein Targeting Key Trends in Publications : Her research spans topics such as effector protein dynamics in Chlamydia trachomatis and Legionella pneumophila , secretion system assays, Golgi complex interactions, lipid droplet associations, and chaperone-substrate complexes. The work emphasizes molecular mechanisms of bacterial invasion and survival within eukaryotic host cells. Laboratory & Team : Dr. Pais collaborates with the Cellular and Molecular Microbiology working group, alongside colleagues like Dr. Abdelhakim Boudrioua, Nicola Gericke, and others, within the broader Faculty of Mathematics and Natural Sciences.

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Annelise Snyderمشاهده پروفایل

استادیار

Western Washington UniversityUnited States

Dr. Annelise Snyder is an Assistant Professor in the Biology Department at Western Washington University (WWU), specializing in immunology and cancer biology. She joined WWU in January 2024 after postdoctoral training at the Fred Hutchinson Cancer Center and Salk Institute. Her research focuses on understanding how macrophages interact with tumor cells during brain metastasis in breast cancer, aiming to identify mechanisms to enhance immune surveillance. She is committed to mentoring students and promoting diversity in STEM through teaching and outreach. Education: Ph.D. in Immunology, University of Washington (2019) B.A. in Biology and Chemistry, Williams College (2011) Research Interests: Dr. Snyder investigates immune evasion strategies employed by cancer cells, particularly in brain metastases. Her lab employs cellular, molecular, and computational tools to study macrophage-tumor interactions. Key areas include tumor immunology, necroptosis pathways, and therapeutic strategies to combat cancer. She emphasizes mentorship to prepare students for biomedical careers. Awards: Tang Prize Foundation Postdoctoral Fellowship (2020-2021) NIH NRSA F32 Predoctoral Fellowship (2017-2019) NSF Graduate Research Fellowship (2013-2017) Advising & Lab: While currently not accepting undergraduate or MS student applications (2024-2025), her lab focuses on macrophage function in metastatic cancer. Past mentorship includes guiding students in immunology techniques and scientific communication.

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Nitin Nitinمشاهده پروفایل

دانشیار

University of CincinnatiUnited States

Nitin Nitin is an Associate Professor in Electrical and Computer Engineering at the University of Cincinnati, with secondary appointments in Computer Science. His research integrates AI, blockchain, and cyber-physical systems for applications in healthcare, energy, and computing. Patents include innovations in vehicle safety systems and data classification. Funded by NIH, DAAD, and OCRI, current projects explore smart contracts, battery management, and medical imaging AI. He directs graduate research in ML-driven GUI testing and blockchain infrastructure. Recipient of multiple teaching awards, he developed courses on smart contract programming and computational engineering.

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Petr Brozمشاهده پروفایل

استاد

University of LausanneSwitzerland

Petr Broz is a Full Professor in the Department of Biochemistry at the Faculty of Biology and Medicine, University of Lausanne (UNIL), where he has been a faculty member since 2017, first as Associate Professor and promoted to Full Professor in 2022. His research focuses on the molecular mechanisms of innate immunity, particularly inflammasome activation and host defense against bacterial pathogens such as Salmonella typhimurium and Francisella tularensis . Appointed Full Professor, UNIL, 2022 Associate Professor, UNIL, 2017–2022 Assistant Professor, Biozentrum, University of Basel, 2013–2017 Postdoctoral Fellow, Stanford University, 2008–2012 PhD in Microbiology, University of Basel, 2006 MSc in Biology, University of Basel, 2002 Dr. Broz’s research explores how the innate immune system detects bacterial pathogens and mounts defensive responses. His work investigates inflammasome assembly, regulation, and function, particularly in the context of interferon signaling and CRISPR/Cas9-based genetic screens. He uses advanced molecular and cellular techniques to dissect host-pathogen interactions and identify novel immune regulators. The 15 most recent publications highlight a strong focus on inflammasome biology, pyroptosis, interferon signaling, and bacterial immune evasion. These works span high-impact journals such as Nature , Science , Nature Immunology , and PNAS , demonstrating consistent contributions to immunology and infection biology. Key themes include the spatiotemporal regulation of inflammasomes, the role of gasdermin D in cell death, and the interplay between interferon responses and inflammasome activation. Scientific awards and recognition include: EMBO Young Investigator (2015) Friedrich Miescher Award (2016) He has received multiple grants from the Swiss National Science Foundation (SNSF) and an ERC Consolidator Grant, supporting his innovative research. Dr. Broz is actively involved in mentoring and has supervised numerous PhD students, master’s students, and postdoctoral fellows. His laboratory integrates genomic, biochemical, and immunological approaches to uncover fundamental mechanisms of immune defense. He is also engaged in undergraduate and postgraduate teaching at UNIL. His research team operates at the forefront of molecular immunology, utilizing cutting-edge technologies such as CRISPR screening and live-cell imaging to study host defense mechanisms in real time. The lab collaborates with national and international partners to advance understanding of infectious diseases and inflammatory processes.

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Monika Maurhofer Bringolfمشاهده پروفایل

استاد

ETH ZurichSwitzerland

Monika Maurhofer Bringolf serves as a Titular Professor and Lecturer at the Department of Environmental Systems Science at ETH Zürich, where she leads the research group focused on Biological Control. Her academic career at ETH Zürich spans over 25 years, beginning as an assistant researcher (1996-1999) and progressing to her current position as senior researcher and lecturer since 2000. Her educational background includes a Dipl. sc. nat. from ETH Zürich (1988) and a Dr. sc. nat. from the Institute of Phytopathology/Plant Sciences at ETH Zürich (1993). These qualifications established the foundation for her extensive research in plant-microbe interactions and biological control mechanisms. Professor Maurhofer Bringolf's research centers on the ecological properties of biocontrol pseudomonads and the complex interactions between crop plants and microorganisms inhabiting the rhizosphere. Her work spans microbial ecology, plant pathology, and biological pest control, with particular emphasis on how plant-beneficial bacteria can improve soil health and plant resistance against pathogens and pests. She investigates the mechanisms governing interactions among biocontrol bacteria, phytopathogens, pest insects, plants, and non-target microbiota. Her research employs approaches ranging from field studies to comparative genomics and transcriptomics to understand how biocontrol bacteria can switch between different ecological niches. Her recent publications demonstrate a strong focus on entomopathogenic bacteria, microbial consortia for pest control, and the suppressive properties of composts against soilborne pathogens. The research shows an increasing trend toward understanding microbial communities and their collective effects on plant health and pest management, with particular attention to how different biocontrol organisms can work synergistically. Winner of the 'golden owl' teaching award from ETH Zurich students in 2014 Winner of the 'golden owl' teaching award from ETH Zurich students in 2017 She actively contributes to scientific policy as a member of the Swiss Expert Committee for Biosafety (SECB) and the Swiss Society for Phytiatry. Her research has been supported by grants from the Swiss National Science Foundation, including projects on microbial consortia for pest control and molecular determinants of insect-plant associated lifestyles of beneficial pseudomonads. Professor Maurhofer Bringolf teaches Plant Pathology I and Plant Pathology III courses at ETH Zürich, maintaining her commitment to educating future plant pathologists and environmental scientists while continuing her active research program.

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Sebastian Acosta Juradoمشاهده پروفایل

پژوهشگر

Pablo de Olavide UniversitySpain

Sebastián Acosta Jurado is a researcher in Molecular Biology and Biochemical Engineering at the Centro Andaluz de Biología del Desarrollo (CABD), affiliated with the research group EXPRESIÓN GENICA EN BACTERIAS DE INTERÉS MEDIOAMBIENTAL . His work focuses on gene regulation in rhizobia, particularly Sinorhizobium fredii HH103 , and its symbiotic interactions with legumes.

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Eric Deedsمشاهده پروفایل

استاد

University of California, Los AngelesUnited States

Eric Deeds is a Professor in the Department of Integrative Biology and Physiology at UCLA, focusing on computational and systems biology. His research bridges structural biology, protein interactions, and mathematical modeling. Education B.S. in Biochemistry, Case Western Reserve University (2001) B.A. in English, Case Western Reserve University (2001) A.M. in Biology, Harvard University (2003) Ph.D. in Biology, Harvard University (2005) His work explores biochemical signaling networks, proteasome assembly, and cellular communication using computational approaches. Recent publications highlight applications in macromolecular interactions , single-cell RNA sequencing , and drug stability analysis . Collaborations span structural biology, pharmacology, and microbiology. Key themes from his 2025-2022 publications include weak interactions in protein assembly , signaling network dynamics , and computational models for disease mechanisms . He has contributed to understanding sex differences in renal metabolism and structural properties of complex drugs . Deeds’ lab integrates mathematical modeling with experimental validation, emphasizing timescale separation in bacterial proteasome assembly and pathway insulation in signaling networks. His interdisciplinary work spans bioinformatics , physical biology , and evolutionary systems biology .

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Patrik M. Bavoilمشاهده پروفایل

استاد

University of Maryland, BaltimoreUnited States

Dr. Patrik M. Bavoil serves as Professor and Chair of the Department of Microbial Pathogenesis at the University of Maryland School of Dentistry, with secondary appointments in Microbiology and Immunology. A leading Chlamydia pathogenesis researcher, he has pioneered work on type III secretion systems and contact-dependent bacterial development models. His academic training includes: Diplôme Universitaire d'Etudes Supérieures (DUES) in Chemistry-Biology, Université de Grenoble, France (1972) Maîtrise and Diplôme d'Etudes Approfondies (DEA) in Biochemistry, Université Claude Bernard, Lyon, France (1975-1976) Ph.D. in Microbiology, UC Berkeley (1982) Postdoctoral Fellowship, UC San Francisco (1982-1984) Postdoctoral Fellowship, Stanford University (1984-1987) Dr. Bavoil's research focuses on molecular mechanisms of Chlamydia infection, particularly type III secretion, polymorphic membrane proteins, and ecopathogenomics. His NIH-funded EPSTI center investigates the triad of Chlamydia trachomatis pathogenomics, vaginal microbiota dynamics, and host genetics through the STING cohort study. Recent publications demonstrate increasing integration of mathematical modeling and multi-omics approaches to understand bacterial development and host-pathogen interactions. His scientific contributions are recognized through: Research Fellowship, American Social Health Association (1982-1984) National Research Service Award, NIAID/NIH (1984-1986) Research Career Development Award, NIAID/NIH (1992-1996) "Professeur Invité" at Institut Pasteur, Paris (1994-1995) Fellow, American Academy of Microbiology (2015-present) As co-director of the NIH-NIAID-funded STI Cooperative Research Center (EPSTI), Dr. Bavoil leads a multi-institutional consortium involving UMB, Duke University, University of Technology Sydney, and University of Idaho. His editorial leadership includes serving as Editor-in-Chief of Pathogens and Disease, and past presidency of the Chlamydia Basic Research Society. His laboratory work centers on the molecular pathogenesis of obligate intracellular bacteria within the Department of Microbial Pathogenesis.

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