جستجوی استاد راهنمای دانشگاهی

Irene Netchine is a leading researcher in pathophysiology of fetal growth , affiliated with Sorbonne University and Saint-Antoine Hospital in Paris, France. Her work focuses on the IGF system and parental imprinting in growth-related disorders, including Silver-Russell syndrome (SRS) , Beckwith-Wiedmann syndrome (BWS) , and Temple syndrome (TS14) . PU-PH (HDR) at Sorbonne University Team Leader at Saint-Antoine Hospital Her research spans genomic imprinting , epigenetic methylation , and IGF signaling , with a focus on molecular mechanisms of 11p15 and 14q32 imprinting disorders. She has developed high-throughput sequencing panels for diagnosing fetal growth anomalies and pioneered iPSC models with balanced methylation for studying imprinting pathologies. Recent publications highlight her expertise in cellular modeling of imprinting disorders, environmental influences on methylation, and clinical-genomic correlations in rare growth syndromes. She leads the RADICO-IDMET cohort and contributes to international consensus statements on SRS management.

• Fetal Growth Disorders
• Genomic Imprinting
• Epigenetics
• +۲ مورد دیگر

Ludovic Tailleux is a Research Professor at the Pasteur Institute , specializing in host-pathogen interactions and tuberculosis immunology . His work focuses on the innate immune response against Mycobacterium tuberculosis, particularly in human dendritic cells and macrophages. He has identified DC-SIGN/CD209 as a critical host cell receptor for M. tuberculosis and collaborates with Laurent Barreiro (University of Montreal) on genetic determinants of immune variation. Education : Not explicitly detailed in the text, but inferred from research depth to include advanced training in immunology/microbiology. Tailleux's research spans innate immunity , antigen presentation , genetic architecture of immune response , and host-directed therapies . His projects include identifying host genetic factors affecting M. tuberculosis interplay and analyzing epigenetic changes in immune cells. The 15 most recent publications highlight trends in zinc toxicity mechanisms , nanocarrier drug delivery , microRNA regulation , and purinergic signaling in TB pathogenesis. He contributes to educational initiatives, including an upcoming MOOC on Tuberculosis (2025) at Pasteur Institute. Collaborative efforts with institutions like University of Montreal and technical teams at Pasteur are central to his work. Tailleux also investigates macrophage polarization , angiogenesis exploitation by TB , and innate immune reprogramming through DNA methylation studies.

• Host-Pathogen Interactions
• Tuberculosis Immunology
• Innate Immunity
• +۴ مورد دیگر

Glenda Comai is a Permanent Researcher (CRCN CNRS) at the Department of Developmental and Stem Cell Biology, CNRS UMR 3738, Institut Pasteur, Paris, where she has worked since 2016 in Prof. Shahragim Tajbakhsh's laboratory. She serves on the Advisory Board of the French Society of Developmental Biology (SFBD) since 2019 and recently obtained her HDR (Habilitation à diriger des Recherches) from Université Paris Saclay in 2024. Her research focuses on understanding the mechanisms underlying tissue patterning during development, with special emphasis on craniofacial muscles. Using 3D-imaging, mouse genetics, and single cell/single nuclear omics approaches, she investigates how heterogeneity at the level of stem cells and myofibers is established and how this impacts muscular genetic disorders. Her work reveals significant differences between extraocular muscle stem cells and those from limb muscles, particularly in their regenerative capacity and molecular signatures. Analysis of her recent publications shows a strong trend toward understanding the transcriptional and epigenetic regulation of muscle stem cell identity, particularly how anatomical location influences stem cell behavior. Her research spans developmental biology, stem cell biology, and muscle physiology, with particular emphasis on craniofacial development and muscle regeneration mechanisms. AFM PRC Grant (2024-2026) ANR JCJC Grant (2021-2024) AFM Trampolin Grant (2020-2021) As Principal Investigator, Dr. Comai leads two major research projects: AFM-Trampolin: Cellular and genetic basis for robustness of cranial myogenic populations (ENCRYPT) and ANR-JCJC: Mechanisms defining functional heterogeneity of anatomically distinct myogenic populations (MUSE). Her laboratory employs advanced techniques including bioimage analysis, confocal microscopy, stem cell culture, and various molecular biology methods to investigate muscle development and regeneration.

• Developmental Biology
• Stem Cell Biology
• Muscle Development
• +۴ مورد دیگر

Odile Sismeiro is a Senior Research Engineer at the Transcriptome and Epigenome Platform within the Biomics Pole at the Institut Pasteur . With over three decades of experience, she has been pivotal in advancing RNA sequencing technologies since 2009. Diplôme Universitaire de Technologie Diplôme d’Études Scientifiques et Techniques from CNAM, Paris Her research intertwines Transcriptomics , Microbial Genetics , and Host-Pathogen Interactions , particularly through developing and applying: DNA array technology Next-Generation Sequencing (NGS) RNA-seq data analysis pipelines Key publication themes highlight: Streptococcus pathogenicity networks RNA-based immune sensing mechanisms Vector-borne disease genetics Microbial biofilm regulation She actively contributes to: Scientific training programs Technological development projects Collaborative research across multiple Institut Pasteur units

• Transcriptomics
• Next-Generation Sequencing (NGS)
• Microbial Genetics
• +۳ مورد دیگر

Thomas Boudier is an Associate Professor at Centrale Méditerranée with additional affiliation as Professor Associate at Sorbonne University's Institute of Biology Paris-Seine (IBPS). His research focuses on bioimage informatics, bridging computer science and biological imaging to develop advanced tools for analyzing complex biological structures. His educational background includes: PhD in Bioimage Informatics from Sorbonne University (1994-1997) Master's in Computer Vision from Nice Sophia Antipolis University (1992-1993) Undergraduate studies in Mathematics from Paris Diderot University (1990-1992) Dr. Boudier's research spans the intersection of computer science and biological imaging, with particular expertise in 3D image analysis and processing. His work has significantly contributed to developing computational methods for analyzing complex biological structures across multiple scales. He has pioneered approaches for electron microscopy image segmentation, 3D reconstruction of cellular structures, and quantitative analysis of tissue organization. His research has important applications in neuroscience, cancer biology, and regenerative medicine, where precise quantification of cellular and subcellular structures is critical. His extensive publication record demonstrates consistent innovation in bioimage analysis, with recent work focusing on deep learning applications for electron microscopy, 3D analysis of neuronal structures, and computational modeling of cardiac cells. His development of specialized software tools like TAPAS, Spot Spine, and CardioVinci has provided the research community with valuable resources for automated image analysis. Throughout his career, Dr. Boudier has maintained strong collaborations across international institutions, including work at Academia Sinica in Taiwan and The Walter and Eliza Hall Institute of Medical Research in Australia. His research laboratory is affiliated with INRIA - National Institute for Research in Digital Science and Technology, where he contributes to advancing computational methods for biological imaging.

• Image Processing
• Biomedical Imaging
• Computer Vision
• +۳ مورد دیگر

Alessandra Pierani is a Professor leading a research team focused on understanding the genetics and development of the cerebral cortex, particularly the role of Cajal-Retzius cells in neural circuit formation. Her work bridges developmental neuroscience, evolutionary biology, and clinical applications, with affiliations at Institut Imagine (Paris) and the Institute of Psychiatry and Neurosciences of Paris (IPNP). Her research investigates how transient neuronal populations influence cortical architecture, with implications for neurological disorders like autism, schizophrenia, and epilepsy. Key areas include neuronal migration, synaptic gene regulation, and the evolutionary origins of higher-order cortical functions. Her team employs mouse and primate models to study developmental mechanisms linking early brain formation to later-onset psychiatric conditions. Recent projects emphasize translational research, collaborating with clinicians and geneticists to develop mouse models for cortical abnormalities and improve diagnosis of neurodevelopmental diseases. The team includes 22 members from 7 nationalities, with associated labs at both institutes.

• Cortical Development
• Neurological Disorders
• Neuronal Migration
• +۳ مورد دیگر

Sameh SELIM is a Teacher-Researcher in Plant Pathology and Molecular Biology at the Université de Picardie Jules Verne, affiliated with the Faculty of Agrosciences and the Department of Agricultural and Animal Sciences. He is a member of the AGHYLE research unit and actively collaborates with institutions like INRA, CNRS, and industry partners such as Bayer and BASF. His research focuses on plant-microbe interactions, alternative methods to chemical control, and the genetic biodiversity of soil microbial communities. SELIM holds a Ph.D. in Biochemistry, Molecular and Cellular Biology from the University of Burgundy (2005) and an MS in Biotechnology and Plant Pathology from El-Suez Canal University (1998). His work emphasizes the development of resistance inducers, fungicide efficacy, and the molecular mechanisms underlying plant defense responses. Recent publications highlight advancements in using Bacillus velezensis BE2 for disease control, transcriptomic analyses of wheat-pathogen interactions, and soil ecosystem service assessments. His research also addresses the durability of resistance mechanisms against pathogens like Zymoseptoria tritici and Mycosphaerella graminicola. SELIM collaborates with global institutions, including the University of Burgundy and ISA Lille, and participates in networks like RMT ELICITRA and the French Society of Phytopathology. His projects span from lab studies to field applications, addressing real-world challenges in sustainable agriculture and disease management.

• Molecular Biology
• Plant Pathology
• Biochemistry
• +۳ مورد دیگر

Guilhem Janbon is a Researcher and Head of the Laboratory of RNA Biology of Fungal Pathogens within the Mycology Department at the Institut Pasteur in Paris, France. He leads a multidisciplinary research team focused on understanding the molecular biology of human fungal pathogens, particularly Cryptococcus neoformans . His work bridges fundamental research on gene expression with translational applications in medical mycology. His primary research interests include: Transcriptome structure and plasticity in fungi Regulation of gene expression via alternative splicing and transcription start site (TSS) usage The role of long non-coding RNAs (lncRNAs) in fungal biology The biogenesis and function of fungal extracellular vesicles (EVs) Host-pathogen interactions and fungal virulence mechanisms His recent publications reveal a strong trend towards understanding dynamic gene regulation in response to environmental stress and its impact on antifungal resistance and virulence. A significant portion of his work explores the potential of fungal extracellular vesicles as both virulence factors and novel vaccine platforms, indicating a forward-looking approach to therapeutic development. Dr. Janbon actively mentors a team of young scientists, including PhD students and post-doctoral researchers, fostering the next generation of mycologists. He leads several research projects funded by the Institut Pasteur, such as those investigating lncRNAs and intron-dependent gene regulation in Cryptococcus . He is also involved in collaborative research, notably as a co-leader of the Pasteur International Unit on Fungal Extracellular Vesicles with partners in the UK and Brazil, highlighting his role in international scientific networks.

• Mycology
• Fungal Pathogenesis
• RNA Biology
• +۸ مورد دیگر

Anavaj Sakuntabhai is the Head of the Ecology and Emergence of Arthropod-borne Pathogens unit at the Institut Pasteur, a UMR unit jointly affiliated with CNRS and INRAE. His research focuses on host-pathogen interactions in vector-borne diseases, particularly dengue, Zika, malaria, and emerging infectious diseases. He leads multiple research projects and is involved in major transversal initiatives such as LabEx IBEID and PICREID. His research interests center on understanding the genetic and immunological basis of host susceptibility to infectious diseases. Key areas include host genetic susceptibility to Zika and dengue viruses, immune crosstalk in COVID-19, and host-parasite interactions in malaria. His work integrates genomics, transcriptomics, and immunology to develop novel strategies for disease prevention and control. The recent publications of Dr. Sakuntabhai and his team reveal strong trends in vector-borne disease research, with a focus on dengue and Zika virus immunology, host genetic responses, and urban transmission dynamics. There is a clear emphasis on translational research, including vaccine development and biomarker discovery, supported by advanced genomic and transcriptomic analyses. He has been principal investigator on several significant projects, including the DENFREE consortium on dengue transmission in Europe and studies on immune responses to SARS-CoV-2 and malaria. His work is supported by major research platforms such as LabEx Milieu Intérieur and LabEx IBEID. Study of immune crosstalk in COVID-19 (COVIMUNE) Host genetic susceptibility to Zika virus Effect of host-parasite interaction on malaria outcome DENFREE consortium – Dengue Framework for Resisting Epidemics in Europe CoSimmGen cohort for human disease studies Dr. Sakuntabhai has mentored numerous graduate students, PhD candidates, postdoctoral researchers, and technicians, many of whom are listed as former members of his research unit. His lab contributes significantly to international collaborative efforts in Southeast Asia and Africa through the PICREID network.

• Host-pathogen interactions
• Genetics
• Immunology
• +۱۰ مورد دیگر

Sebastien Moreau is a Lecturer in the Department of Animal Biology and Genetics at Université François-Rabelais. He is affiliated with the UMR CNRS 7261 - Research Institute on Insect Biology (IRBI) and the Faculty of Sciences and Techniques. His research focuses on four main areas: non-lethal identification methods for wild bees, innovative composting technologies, functional ecology of agricultural landscapes, and molecular mechanisms governing host-parasitoid interactions in hymenoptera. His work combines field studies with molecular biology techniques, bioinformatics, and biochemical analysis. Key projects include EXAPICO (2025-2028) for wild bee conservation and development of the Compostou shared composting system. He has collaborated extensively with regional stakeholders including Zéro Déchet Touraine, CETU Innophyt, and participated in national initiatives like Trame Verte et Bleue. Dr. Moreau has authored/co-authored over 35 peer-reviewed publications since 1997, with recent work emphasizing genomic studies of parasitic wasps and venom protein characterization. His applied ecology research addresses both environmental sustainability (composting systems) and fundamental biological questions (parasitoid-host molecular dialog). Teaching responsibilities include courses in Applied Ecology, Waste Prevention, Animal Biology, Histology, Cell Biology, and Entomology. He has developed innovative pedagogical projects like the 'Effet Papillon' initiative linking student action to climate change mitigation. Professional service includes jury participation for national flower meadow competitions and advisory roles in regional ecological planning. His work exemplifies interdisciplinary research spanning molecular biology to community-based environmental solutions.

• Wild Bees Conservation
• Composting Technology
• Functional Ecology
• +۳ مورد دیگر

Milena Hasan is a Researcher at the Institut Pasteur in Paris, France, specializing in UTechS Single Cell Biomarkers unit. Her work focuses on cutting-edge single-cell transcriptomics , immune profiling , and cytometry data analysis across diverse conditions including viral infections, autoimmune diseases, and cancer immunotherapy. Lead investigator for multiple projects (TPAI, TTP, VARIANCE) involving single-cell technology training and advanced immune response analysis Key contributor to the Milieu Intérieur program studying immune system heterogeneity She actively develops tools for multi-omics data integration and leads courses on Single Cell Gene Expression and Beyond (2022, 2025) and Advanced Immunology (2025). Her research spans host-pathogen interactions , T cell dynamics , and inflammatory disease mechanisms through innovative technologies like spectral cytometry and single-cell proteomics.

• Single-cell transcriptomics
• Immunology
• Infectious disease research
• +۵ مورد دیگر

Antoine Gessain is a leading medical virologist and Head of Structure at the Oncogenic Virus Epidemiology and Pathophysiology (EPVO) unit at the Institut Pasteur in Paris. He received his MD and PhD from Parisian universities and has been instrumental in advancing research on retroviruses and oncogenic viruses since the unit's founding in 2001. He leads multiple research projects and collaborates with international institutions across Central Africa, French Guiana, and Peru. His research interests include: Virology and molecular epidemiology of HTLV-1, HHV-8, and simian foamy viruses Zoonotic transmission of retroviruses from primates to humans Genetic diversity and global dissemination of oncogenic viruses Pathogenesis of HTLV-1-associated diseases such as myositis and neuromyelopathy Immunological responses to retroviral infections His recent publications (2022–2025) reflect a strong focus on emerging viral threats, structural virology, and the molecular mechanisms of viral entry and immune neutralization. Notably, his team has contributed key insights into the structure of foamy virus envelope proteins, seroreactivity to ebolaviruses in Central Africa, and the epidemiology of HTLV-1 transmission in rural populations. Dr. Gessain has received no explicitly mentioned scientific awards in the provided text. However, his role as principal investigator on multiple funded projects and his extensive publication record underscore his scientific impact. He is actively involved in mentoring researchers and post-doctoral fellows, though specific PhD advisees are not listed. His work is supported by long-term collaborations with the Réseau International des Instituts Pasteur, CIRMF in Gabon, and Peruvian academic institutions. He also contributes to teaching at the Institut Pasteur, co-directing courses in systematic virology and infectious disease circulation. His research unit operates at the intersection of basic virology, public health, and clinical applications, with strong links to hospital departments and animal care facilities for translational research.

• Virology
• Epidemiology
• Retrovirology
• +۱۲ مورد دیگر

Sebastian Baumgarten is the Head of the 'Parasite RNA Biology' Group at the Institut Pasteur, France, a position he has held since June 2021. He is affiliated with the Department of Biology of Host-Parasite Interactions. Previously, he was a post-doctoral researcher at the same institute from 2016 to 2021. His educational background includes a Ph.D. (2013–2016) and MSc (2012–2013) from the Red Sea Research Center at King Abdullah University of Science and Technology, Saudi Arabia, and a BSc (2009–2012) from the University of Tübingen, Germany. His research centers on RNA biology in malaria parasites, particularly focusing on RNA modifications such as m6A and tRNA methylation, epigenetic regulation, and post-transcriptional gene control in Plasmodium falciparum . He employs advanced genomic techniques including CRISPR, RNAseq, and ChIPseq to study gene regulation and immune evasion mechanisms in protozoan parasites. His recent publications reveal a strong trend in understanding how RNA modifications influence parasite development, stress response, and antigenic variation. His work bridges molecular parasitology with epitranscriptomics, contributing significantly to the understanding of gene regulation in malaria parasites. Notable scientific contributions include studies published in Nature Microbiology , mBio , EMBO Reports , and Life Science Alliance , focusing on m6A methylation, RUF6 ncRNA interactions, and cohesin-mediated gene repression. He has supervised or collaborated with several researchers including post-doctoral fellows, PhD students, and technicians within his team. His group is actively involved in uncovering the molecular mechanisms of parasite survival and immune evasion, with potential implications for antimalarial drug and vaccine development. The 'Parasite RNA Biology' group operates within the Institut Pasteur's ecosystem, leveraging interdisciplinary platforms for genomics, imaging, and functional analysis to advance understanding of malaria parasite biology.

• RNA modifications
• Parasitology
• Malaria
• +۱۲ مورد دیگر

Fabienne GUERARD is a University Professor at the University of Western Brittany (UBO) since 2008, specializing in marine biotechnology and enzymatic engineering. Her research focuses on enzymatic hydrolysis of marine substrates for high-value active molecule production, collagen matrix development for regenerative medicine, and bioadhesion mechanisms in Pacific oyster larvae. She also investigates immune responses in marine organisms like the Manila clam infected by Vibrio species. Deputy Director of the Marine Environmental Sciences Laboratory (LEMAR, UMR 6539) since 2012 Project Manager for Biotechnologies at UBO and co-facilitator of the IUEM cross-disciplinary axis 'Marine Biotechnologies' Her teaching contributions include leading the LMD reform for the IUP Innovation in Food Industries program, creating the VALBIOREM specialty in the Master 2 SBM, and contributing to the accreditation of the ESIAB agri-food engineering training's marine biotechnology section. Prof. Guerard has managed major research projects such as FP6 SEAFOODplus, INTERREG-funded BIOTECMAR, and collaborates extensively with industry through Competitiveness Clusters like CapBioTeK and Technopoles in Brest/Quimper. Her work bridges academia and innovation, particularly in valorizing marine by-products and developing bioactive materials.

• Marine Biotechnology
• Biochemistry
• Enzymatic Engineering
• +۳ مورد دیگر

Hélène Thomas is a Senior Lecturer HDR at La Rochelle University, affiliated with the LIENSs (LIttoral ENvironment and Societies) laboratory (UMR 7266). She serves as CNRS Scientific Institute referent for INEE and is an elected member of CNU 65 (Cell Biology). Her research integrates molecular and cellular tools to study defense mechanisms in marine organisms under environmental stressors. Research Interests: Dr. Thomas specializes in immunotoxicology and ecophysiology of marine organisms, particularly using molluscs (oysters, mussels, scallops) and fish as bioindicators. Her work focuses on biomarker development for assessing impacts of microplastics, nanomaterials, trace elements, pesticides, and organic pollutants in coastal ecosystems. She investigates host-pathogen interactions across biological organization levels to develop conservation strategies for marine environments. Publication Trends: Recent publications (2021-2025) reveal concentrated research on microplastic effects in bivalves, multi-biomarker port monitoring across Mediterranean and Atlantic sites, and advanced analytical methods for contaminant screening. Her work bridges field studies with laboratory analyses to address emerging pollutants and climate change impacts on marine health. Scientific Awards: None listed. Advising and Grants: She has supervised doctoral students and post-doctoral researchers through national programs including AQUAECOs (2018-2021), Marina (2015-2018), and PRECODD Discobiol (2007-2010), plus European projects like NANORETOX (2008-2012) and ANCORIM (2008-2012). She coordinates France-Norway international programs and provides technical support to Kendari City for water cycle management (2020-2024). Labs and Teams: Former Head of AMARE Research Team (2014-2018), she currently leads research within LIENSs laboratory. Her team collaborates with University of Seville and MNHN on WIBE information system development for environmental monitoring, utilizing SAFAS XENUS laboratory facilities for coastal zone analyses.

• Immunotoxicology
• Ecophysiology
• Marine Biology
• +۳ مورد دیگر