Ludovic Tailleux

Ludovic Tailleux is a Research Professor at the Pasteur Institute, specializing in host-pathogen interactions and tuberculosis immunology. His work focuses on the innate immune response against Mycobacterium tuberculosis, particularly in human dendritic cells and macrophages. He has identified DC-SIGN/CD209 as a critical host cell receptor for M. tuberculosis and collaborates with Laurent Barreiro (University of Montreal) on genetic determinants of immune variation.

• Education: Not explicitly detailed in the text, but inferred from research depth to include advanced training in immunology/microbiology.

Tailleux's research spans innate immunity, antigen presentation, genetic architecture of immune response, and host-directed therapies. His projects include identifying host genetic factors affecting M. tuberculosis interplay and analyzing epigenetic changes in immune cells. The 15 most recent publications highlight trends in zinc toxicity mechanisms, nanocarrier drug delivery, microRNA regulation, and purinergic signaling in TB pathogenesis.

He contributes to educational initiatives, including an upcoming MOOC on Tuberculosis (2025) at Pasteur Institute. Collaborative efforts with institutions like University of Montreal and technical teams at Pasteur are central to his work. Tailleux also investigates macrophage polarization, angiogenesis exploitation by TB, and innate immune reprogramming through DNA methylation studies.