جستجوی استاد راهنمای دانشگاهی

Dr. Gary Hon is an Assistant Professor at UT Southwestern Medical Center affiliated with the Cecil H. and Ida Green Center for Reproductive Biology Sciences and the Lyda Hill Department of Bioinformatics. He leads a research program focused on decoding the complexity of the human genome through two primary directions: understanding the molecular basis of cell state for regenerative medicine applications, and elucidating how non-coding variants contribute to development and disease. His lab employs integrative techniques at the interface of gene regulation, epigenetics, genome engineering, single-cell genomics, and bioinformatics. His research interests span genomics, epigenetics, bioinformatics, gene regulation, stem cell biology, and disease mechanisms. Dr. Hon earned his graduate degree from UC San Diego's Bioinformatics and Systems Biology Program and completed post-doctoral training in Dr. Bing Ren's lab before joining UT Southwestern in 2015. Dr. Hon has received significant recognition including the CPRIT Scholar award and NIH Director’s New Innovator Award. His recent publications demonstrate a focus on advanced genomic techniques including Perturb-Seq optimization, single-cell transcriptomics in cancer and reproductive biology, enhancer network mapping, and stem cell modeling of human development.

• Genomics
• Epigenetics
• Bioinformatics
• +۳ مورد دیگر

Jeff Anderson is an Associate Professor in the Department of Botany and Plant Pathology at Oregon State University (OSU), affiliated with the College of Agricultural Sciences. His research focuses on molecular mechanisms of bacterial pathogenesis and plant disease resistance, particularly the inter-kingdom chemical signaling between Pseudomonas syringae and Arabidopsis . He investigates how bacterial pathogens use plant-derived metabolites to activate virulence and how plants activate immune responses. His lab employs genetic, biochemical, and omics approaches to study host-pathogen interactions. Anderson holds a Ph.D. from Cornell University (2006). He teaches courses in biology and functional genomics, including BI221 and BDS478/578. His research has been supported by grants such as the NSF CAREER award (2020), which funds studies on plant-pathogen metabolic interfaces. He has mentored multiple students, including PhD candidate Dylan Gregory and undergraduates Sarah Khan, Grace Norman, and Gustavo Velazquez. Key research trends in his articles include host-derived metabolite signaling, plant immune activation via pattern-triggered immunity, and bacterial virulence regulation. He has also explored the role of proline depletion in plant defense and the molecular mechanisms of thiamin priming in crop protection. Awards: 2025 R.M. Wade Award for Excellence in Teaching 2025 Registry of Distinguished Teachers 2021 Savery Outstanding Young Faculty Award 2020 NSF CAREER Award Anderson leads a research group that emphasizes translational outcomes in plant disease management. His work on metabolite signaling and host-pathogen interactions has implications for developing crop protection strategies against bacterial pathogens.

• Molecular mechanisms of bacterial pathogenesis
• Plant disease resistance
• Inter-Kingdom chemical signaling between bacteria and plants
• +۴ مورد دیگر

Nouria Hernandez is a distinguished academic and researcher currently serving as Professor and Director of the Center for Integrative Genomics at the University of Lausanne. Her career spans multiple prestigious institutions, including Cold Spring Harbor Laboratory and the Howard Hughes Medical Institute. EDUCATION Baccalaureate, Collège de Genève (1976) Diploma in Biology, University of Geneva (1980) Ph.D. in Molecular Biology, University of Heidelberg (1983) Her research focuses on RNA polymerase III transcription regulation and its genomic implications. She has received significant recognition for her contributions, including the Max Cloëtta Foundation Prize and memberships in EMBO and Academia Europaea. HONORS & AWARDS Swiss National Science Foundation post-doctoral fellowship (1983-1984) Damon Runyon-Walter Winchell Cancer Fund fellowship (1985-1986) Rita Allen Foundation scholarship (1989-1994) EMBO member (2007) Executive board, Swiss Academy of Sciences (2007) Prof. Dr. Max Cloëtta Foundation Prize (2007) Member of the Academia Europaea (2013)

• Transcription of small nuclear RNA genes
• Regulation of RNA polymerase III transcription
• Genomic regulation of RNA polymerase III transcription
• +۱ مورد دیگر

Heath MacMillan is an Associate Professor in the Department of Biology at Carleton University, Faculty of Science. His research focuses on integrative insect physiology, particularly how environmental stressors like extreme temperatures, microplastics, and dietary changes affect molecular, biochemical, and whole-organism performance. Research Themes: Cold tolerance mechanisms, ionoregulatory collapse, microplastic pollution impacts, thermal acclimation physiology, and nutritional ecology for edible insects. Model Systems: Drosophila melanogaster, Gryllodes sigillatus, Aedes aegypti, and tropical butterflies. Techniques: Transcriptomics, metabolomics, in vitro osmoregulation assays, thermal gradient devices, and fluorescent microplastic tracking. His lab collaborates with Environment and Climate Change Canada, Dr. Jennifer Provencher, and Entomo Farms to address both fundamental physiological questions and applied problems in sustainable insect protein production. Current work explores how thermal plasticity and cross-tolerance mechanisms interact with ecological stressors like hypoxia and desiccation. Publications highlight his team's development of the ionoregulatory collapse model for cold tolerance, discovery of microplastic impacts on cricket growth, and characterization of thermal acclimation's role in maintaining central nervous system function. Research integrates molecular mechanisms with ecological predictions about species distribution and abundance under climate change. Lab opportunities emphasize collaborative, interdisciplinary work across physiology, biochemistry, and ecology. Graduate students and postdocs are encouraged to develop independent projects within the lab's existing frameworks. Undergraduates gain hands-on experience through volunteer work and independent studies.

• Insect physiology
• Thermal stress responses
• Cold tolerance mechanisms
• +۶ مورد دیگر

Paul A. Harding is a Professor and Chair of the Biology department at Miami University. His research focuses on understanding the role of heparin-binding EGF-like growth factor (HB-EGF) in reprogramming cells into brown adipose tissue (BAT)-like phenotypes. He leads the Cell, Molecular and Structural Biology Graduate Program and is affiliated with the Center for Animal Behavior and Center for Neuroscience and Behavior. His work explores HB-EGF/ADAM12S interactions in metabolic regulation and therapeutic applications for obesity and diabetes. Research interests include adipose tissue biology, cellular reprogramming mechanisms, and the molecular pathways governing energy expenditure. His lab uses adenoviral gene delivery systems to investigate BAT-like cell induction in human adipose tissue. Experimental plans include in vivo studies to validate cellular reprogramming efficacy. No scientific awards are explicitly listed. Courses taught include Molecular Techniques (BIO 464), Human Physiology (BIO 161), and Advanced Biotechnology Applications (BSC 416). Current projects involve exploring FGF2 and Klf3's roles in HB-EGF-mediated stem-like state induction.

• Molecular Biology
• Cellular Biology
• Obesity Research
• +۳ مورد دیگر

Prof. G.V. Shivashankar is a Full Professor of Mechano-Genomics at ETH Zurich and holds a joint appointment at the Paul Scherrer Institute (PSI), Switzerland. He previously served as Deputy Director of the Mechanobiology Institute (MBI) at the National University of Singapore (NUS), where he also held the IFOM-NUS Chair Professorship. His research focuses on nuclear mechanics, genome regulation, and cancer diagnostics, integrating optical imaging, machine learning, and functional genomics. Educated at The Rockefeller University (PhD, 1994–1999) and with postdoctoral training at NEC Research Institute, he has led groundbreaking studies on nuclear mechanogenomics and mechano-driven cell fate transitions. Awards include the Birla Science Prize (2006), Swarnajayanthi Fellowship (2007), and EMBO membership (2019). His work bridges disciplines, exploring how mechanical forces influence nuclear architecture and gene regulation. He leads the Laboratory of Multiscale Bioimaging at PSI, collaborating with IFOM in Milan. Current projects include developing nuclear biomechanical markers for early cancer diagnosis and AI-driven analysis of chromatin dynamics. Grants include support from the Mechanobiology Institute, Ministry of Education (Singapore), and the IFOM-MBI Joint Lab. Notable achievements include detecting chemoresistant cancer cells via chromatin biomarkers and reprogramming fibroblasts for tissue regeneration. His lab actively mentors students and collaborates globally on mechanobiology applications in health and disease.

• Mechano-Genomics
• Nuclear Mechanics
• Genome Regulation
• +۳ مورد دیگر

John A. Pulikkan, PhD, is an Assistant Professor in the Department of Cell Biology, Neurobiology and Anatomy at the Medical College of Wisconsin. His research focuses on deciphering the interplay between transcription factors and chromatin dynamics in normal and malignant hematopoietic stem cells, with a particular emphasis on acute myeloid leukemia (AML). He leads the Pulikkan Lab, dedicated to identifying novel therapeutic targets for leukemia treatment through genetic, epigenetic, and biochemical approaches in mouse models and human primary leukemic cells. Dr. Pulikkan earned his PhD from Ludwig Maximilian University of Munich, Germany, where his work elucidated mechanisms of C/EBPα in hematopoiesis. His postdoctoral research at the University of Massachusetts Medical School led to the discovery of AI-10-49, a small molecule inhibitor targeting CBFβ-SMMHC in leukemia. This work demonstrated the feasibility of targeting 'undruggable' oncogenic transcription factors, with AI-10-49 now advancing toward clinical development. His research interests span three key areas: (1) transcription factor-chromatin dynamics in hematopoiesis, (2) transcriptional deregulation in AML, and (3) functional roles of non-coding RNAs in leukemia. Notable contributions include insights into MYC chromatin dynamics inhibition and SWI/SNF/PRC axis disruption in cancer. Awards: ASH Scholar Award, Alex's Lemonade Stand Foundation Young Investigator Award, Lauri Strauss Leukemia Foundation Discovery Grant Lab Focus: Translational research bridging basic science and clinical leukemia therapy Key Findings: Role of ADAR2 RNA editing in AML, hijacking of PU.1 antisense promoters by CBF fusions, and N-MYC survival pathways in inv(16) AML

• Chromatin Dynamics
• Hematopoiesis
• Leukemia Biology
• +۳ مورد دیگر

Katherine G. Quinn, PhD serves as Associate Professor and Director within the Department of Psychiatry and Behavioral Medicine at the Medical College of Wisconsin (MCW). Her leadership roles include Associate Director of the Center for AIDS Intervention Research and Co-Director of the Prevention and Implementation Sciences Training (PAIST) Lab, where she advances community-engaged public health research. Dr. Quinn's educational background includes a PhD in Public and Community Health from MCW, an AM in Social Service Administration from the University of Chicago, and a BA in Social Welfare and Justice from Marquette University. Her research critically examines how intersectional discrimination and stigma—particularly racism and anti-LGBTQ+ bias—impact health outcomes for Black sexual and gender minorities. Key focus areas include HIV treatment disparities, PrEP access, mental health, community violence, and resilience strategies. Analysis of her recent publications reveals a consistent emphasis on qualitative and mixed-methods approaches to understanding health inequities. Her work spans HIV prevention, telehealth adaptations for rural populations, vaccine hesitancy in Black communities, and the syndemic effects of structural violence. A distinctive thread across her scholarship is centering community voices to develop culturally responsive interventions. Through the PAIST Lab and Center for AIDS Intervention Research, Dr. Quinn mentors emerging researchers and implements training programs in prevention science. Her operational framework prioritizes community partnership in all research phases, from design to dissemination. Current projects address doula integration for birth equity, self-collected HIV monitoring tools, and navigating healthcare systems amid pervasive medical mistrust.

• HIV Research
• Health Disparities
• Intersectionality
• +۷ مورد دیگر

Steven Yukl, MD is a Physician Scientist at the University of California, San Francisco (UCSF) and the San Francisco VA. His research focuses on understanding mechanisms of HIV latency and SARS-CoV-2 transcriptional regulation. He has conducted studies since 2005 on viral reservoirs, tissue-specific HIV persistence, and immune interactions. His work includes translational research on latency-reversing agents and antiretroviral therapy optimization. Education: MD from University of Michigan (2000), B.S. in Chemistry from Stanford University (1995). Residency in Internal Medicine/Pediatrics (Duke University, 2004) and Infectious Diseases Fellowship (UCSF, 2008). Research interests include HIV reservoir quantification, viral transcription dynamics, and host-pathogen interactions. His recent studies explore SARS-CoV-2 subgenomic RNA mechanisms and their impact on pathogenesis. Collaborations involve advanced transcriptomic and genomic approaches to dissect viral persistence and immune responses. Key contributions include developing novel assays to measure HIV transcription profiles and analyzing tissue-specific differences in viral latency. His work bridges basic science and clinical applications in HIV cure strategies.

• HIV Research
• Virology
• Latent Infection Mechanisms
• +۳ مورد دیگر

Satchidananda Panda is a Professor at the Salk Institute for Biological Studies, leading the Regulatory Biology Laboratory. His research focuses on circadian rhythms and their impact on health, metabolism, and disease. He discovered the role of melanopsin in regulating circadian clocks and pioneered studies on time-restricted eating (TRE), showing its benefits in preventing obesity, diabetes, and metabolic disorders. His work integrates basic science with translational research, leveraging clinical trials and wearable technology to improve public health. Education: PhD in Molecular Biology from The Scripps Research Institute (2001), Postdoctoral Research at Genomics Institute of the Novartis Research Foundation (2001-2005). Research Interests: Circadian regulation of metabolism, sleep, and aging. Key discoveries include the molecular mechanisms of light sensing, circadian disruption's role in chronic diseases, and TRE's therapeutic potential. Current projects explore TRE's applications in shift workers, cancer patients, and individuals with metabolic syndrome. Key Innovations: Developed the MyCircadianClock app to collect global data on eating/sleep patterns, enabling large-scale studies. Collaborates with the Wu Tsai Human Performance Alliance to explore exercise and circadian health links. Awards: 2023 AAAS Fellow, 2014 Julie Martin Mid-Career Award, 2006 Dana Foundation Award, and Pew Scholar honor (2006). Labs/Teams: Panda Lab at Salk focuses on multi-omics analysis and translational studies. Active in clinical trials testing TRE in firefighters, shift workers, and diabetic patients.

• Circadian Rhythms
• Metabolism
• Sleep Science
• +۴ مورد دیگر

Dr. Joseph Pegler is a Lecturer in molecular plant biology at the School of Environmental and Life Sciences, University of Newcastle. His research focuses on improving crop yields under abiotic stress through understanding plant genetic and molecular responses, particularly involving microRNA pathways and nutrient transport. He holds a PhD in Biological Sciences from the University of Newcastle and has received awards including the 2024 Early Career Researcher Excellence Award and the 2021 Fulbright Future Scholarship. Education Doctor of Philosophy (Biological Sciences), University of Newcastle Bachelor of Biotechnology (Honours), University of Newcastle Bachelor of Biotechnology, University of Newcastle Research Interests Dr. Pegler’s work addresses food security challenges via molecular mechanisms in plants, including RNA silencing, abiotic stress responses, and sugar transport pathways. He explores how microRNAs regulate plant adaptation to environmental stressors like drought, salinity, and heavy metals. His research also extends to optimizing cannabinoid production in Cannabis sativa and enhancing crop resilience through genetic manipulation. Teaching & Service He teaches courses in plant adaptation, biochemistry, and molecular genetics, and holds administrative roles such as Deputy Program Convenor for the Bachelor of Biotechnology and College of Engineering, Science and Environment Board member. He has received multiple teaching awards, including the 2024 Teaching Excellence Award (Highly Commended). Funding & Grants Dr. Pegler has secured over $238,891 in grants, including funding for studies on environmental pollutants and plant-based solutions like Moringa’s PFAS sequestration. Recent grants include the 2024 Hunter Medical Research Institute project and an Australian Academy of Science grant. Collaborations His international collaborations include work at the University of Minnesota (Fulbright Fellowship) and research on cannabis at the University of Newcastle. He actively engages in interdisciplinary projects, emphasizing cross-sector solutions to global challenges.

• Molecular Plant Biology
• Abiotic Stress
• Plant Physiology
• +۳ مورد دیگر

Dr. Tim Sherman is a Professor in the Department of Biology and Adjunct Associate Professor in the Department of Marine Sciences at the University of South Alabama. He holds a B.S. in Biology from Arkansas Tech University (1981) and a Ph.D. in Biochemistry from Texas A&M University (1988). His research focuses on plant cell biology, biochemistry, and the physiology of aquatic and marine species. Key areas include molecular interactions between seagrasses and pathogens, stress tolerance mechanisms in halophytic algae, and nitrogen/carbon metabolism in marine algae. Current projects investigate seagrass die-offs, invasive species impacts, and parasite-plant host interactions. Dr. Sherman’s recent work emphasizes seagrass pathology and environmental stress responses. His articles span marine ecology, molecular biology, and plant physiology, with notable contributions to understanding invasive species dynamics and disease mechanisms. Grants: NSF MRI grant for a light sheet microscope (PI: Tom Rich). Lab Focus: Examines thermal responses of marine fish to climate change and anthropogenic nutrient effects on plant competition. His advisory work includes mentoring students in ecology, molecular biology, and environmental science. Collaborations span seagrass conservation, microbial diversity, and parasitic barnacle-host interactions.

• Plant Physiology
• Marine Biology
• Biochemistry
• +۳ مورد دیگر

Professor Pipsa Saharinen is a faculty member at the University of Helsinki, affiliated with the Department of Biochemistry and Developmental Biology within the Faculty of Medicine . Her research focuses on vascular biology, lymphatic system dynamics, and cancer therapy, particularly investigating mechanisms regulating endothelial cell behavior and vascular integrity. She holds grants from the Sigrid Jusélius Foundation, Cancer Foundation (Syöpäsäätiö), and the Academy of Finland, supporting projects like Biological Barrier Mechanics and Disease and Translational Cancer Medicine Program . Her work includes collaborations in the Helsinki In Vivo Animal Imaging Platform , enhancing translational research capabilities. Her scientific contributions span over 75 publications, emphasizing vascular mechanotransduction, lymphangiogenesis, and targeted therapies for metastatic cancers. Key findings include cytoskeletal regulation in lymphatic endothelium resilience and the protective role of Pim3 kinase in vascular barriers. Awards: Pfizer Scholar in Cancer Research (2001), Best Biomedical Thesis (2004) Supervised: Postdoctoral researchers (e.g., Anne Pink, Elina Kiss) and doctoral candidates in biomedical and integrative life sciences. Current research explores molecular mechanisms underlying vascular barrier function and metastasis, with clinical implications for cancer treatment and lymphatic disorders.

• Biomedicine
• Cell and Molecular Biology
• Vascular Biology
• +۳ مورد دیگر

Lennart Beckmann is an Clinical Assistant Professor at the University Medical Center Hamburg-Eppendorf, affiliated with the II. Medical Clinic and Polyclinic under the Faculty of Medicine. His research focuses on hematology and oncology, particularly investigating coagulation mechanisms in cancer and hematological disorders. He has contributed to studies on tumor-induced thrombosis, immune checkpoint inhibitors, and the role of myeloperoxidase in anticoagulant therapies. Beckmann has published extensively in journals like J Thromb Haemost and Hamostaseologie , addressing topics such as extracellular vesicle-mediated coagulation and small-molecule inhibitors for factor XI. He holds awards including the 2029 Young Investigator Award (DGHO) and the 2019 Dieter Kurt Hossfeld Prize for clinical oncology/hematology. His work bridges clinical research and translational medicine, with a focus on improving understanding of thrombotic complications in cancer and autoimmune conditions. Collaborations include studies on drug repurposing (e.g., bacitracin, rutin) and mechanisms of acquired protein S deficiency. Beckmann’s research also examines the interplay between inflammation, monocyte activation, and coagulation pathways in diseases like antiphospholipid syndrome and acute myeloid leukemia.

• Hematology
• Oncology
• Thrombosis
• +۳ مورد دیگر

Max Staller is an Assistant Professor in the Department of Molecular and Cell Biology at the University of California, Berkeley, affiliated with the College of Letters & Science and the Center for Computational Biology. His lab focuses on understanding how transcriptional activation domains regulate gene expression through interdisciplinary approaches combining experimental, computational, and theoretical methods. Research Interests: Transcriptional regulation mechanisms in development and stress responses Functional analysis of intrinsically disordered protein domains Machine learning applications in protein sequence-function prediction Evolutionary dynamics of transcription factors Grants & Collaborations: Lead investigator on the NSF-funded PlantSynBio project (2021) for identifying transcriptional activation domains across plant species. Collaborates with the Cohen Lab (Washington University) on mutational scanning studies. Labs & Affiliations: Director of the Staller Lab, which integrates high-throughput experiments with computational modeling. Active in the Berkeley Bioscience community and the Center for Computational Biology.

• Transcriptional Regulation
• Gene Expression
• Intrinsically Disordered Proteins
• +۳ مورد دیگر