Steven Yukl

Steven Yukl, MD is a Physician Scientist at the University of California, San Francisco (UCSF) and the San Francisco VA. His research focuses on understanding mechanisms of HIV latency and SARS-CoV-2 transcriptional regulation. He has conducted studies since 2005 on viral reservoirs, tissue-specific HIV persistence, and immune interactions. His work includes translational research on latency-reversing agents and antiretroviral therapy optimization.

Education: MD from University of Michigan (2000), B.S. in Chemistry from Stanford University (1995). Residency in Internal Medicine/Pediatrics (Duke University, 2004) and Infectious Diseases Fellowship (UCSF, 2008).

Research interests include HIV reservoir quantification, viral transcription dynamics, and host-pathogen interactions. His recent studies explore SARS-CoV-2 subgenomic RNA mechanisms and their impact on pathogenesis. Collaborations involve advanced transcriptomic and genomic approaches to dissect viral persistence and immune responses.

Key contributions include developing novel assays to measure HIV transcription profiles and analyzing tissue-specific differences in viral latency. His work bridges basic science and clinical applications in HIV cure strategies.