جستجوی استاد راهنمای دانشگاهی

Professor Chris Holmes is a Professor of Biostatistics at the University of Oxford, where he moved from Imperial College London in February 2004. He is a Fellow at St Anne's College and works in the Department of Statistics. His research focuses on applications and statistical methods development in genomic sciences and genetic epidemiology, holding a prestigious Programme Leaders Grant in Statistical Genomics from the Medical Research Council. Prior to his position at Oxford, Professor Holmes completed his doctorate in Bayesian statistics at Imperial College London, investigating novel nonlinear pattern recognition methods. This was followed by a post-doctoral position and then a lectureship at Imperial. Before his academic career, he worked in industry for several years in scientific computing, developing techniques for real-time pattern recognition models in defense and SCADA systems. Professor Holmes has a broad interest in the theory, methods and applications of statistics and statistical modeling, with a particular foundation in Bayesian statistics which he views as providing a unified framework for stochastic modeling and information processing. His specific research interests include: Bayesian statistics and stochastic simulation Markov chain Monte Carlo methods Pattern recognition and nonlinear, nonparametric methods Spatial statistics Statistical genetics and genomics Genetic epidemiology His recent publications (2023-2025) demonstrate a strong focus on the intersection of biostatistics, artificial intelligence, and healthcare applications. His work spans multiple domains including AI-driven disease classification in neurology, genomic data analysis for health equity, machine learning tools for healthcare prediction, and addressing bias in medical AI systems. A notable trend across his research is the application of advanced statistical methods to solve pressing problems in genomics, epidemiology, and medical diagnostics, with an increasing emphasis on health equity and the ethical implications of AI in healthcare. Professor Holmes currently supervises PhD students Oscar Clivio, Sahra Ghalebikesabi, and Natalia Garcia Martin. His research is supported by multiple grants, including the MRC Programme Leaders Grant in Statistical Genomics which funds his work in statistical genomics. He is actively involved in three research groups at Oxford that reflect the breadth of his scholarly interests: Computational Statistics and Machine Learning Statistical Genetics and Epidemiology Statistical Theory and Methodology

• Bayesian statistics
• Stochastic simulation
• Markov chain Monte Carlo
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Cheryl Walker, Ph.D., is a Professor in the Departments of Molecular and Cellular Biology, Medicine, and Molecular and Human Genetics at Baylor College of Medicine. She serves as Director of the Center for Precision Environmental Health and Co-Leader of the Chromatin Biology Program at the Dan L Duncan Comprehensive Cancer Center. Her research focuses on gene-environment interactions, epigenomics, and the molecular mechanisms underlying diseases such as cancer, fibroids, and non-alcoholic fatty liver disease (NAFLD). Key areas include the role of chromatin remodelers like SETD2 in genomic stability and their dual functions in cytoskeletal dynamics. She has pioneered studies on how early-life environmental exposures, such as endocrine-disrupting chemicals (EDCs), reprogram the epigenome to increase disease susceptibility later in life. Dr. Walker’s work is funded by NIH and DOD grants, including leadership of the TaRGET II Consortium for environmental epigenomics. Her lab employs cutting-edge technologies like ChIP-seq and RNA-seq to study epigenetic reprogramming. Notable contributions include discoveries linking SETD2 methylation to microtubule stability and genomic integrity, and identifying epigenetic signatures of environmental exposures in health disparities research. Education: Ph.D. in Molecular Biology Affiliations: Baylor College of Medicine, Gulf Coast Center for Precision Environmental Health Her awards include election to the National Academy of Medicine and fellowships in the American Association for the Advancement of Science (AAAS) and American Thoracic Society (ATS). The lab actively collaborates on translational projects, including biomarker development and disaster-related health studies following events like Hurricane Harvey. Key Research Themes: Epigenetic drivers of cancer and fibrosis Environmental epigenomics and disease risk Chromatin-cytoskeleton cross-talk in disease

• Epigenomics
• Cancer Biology
• Molecular Genetics
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Anthony Brown is an Associate Professor in the Department of Cell and Developmental Biology at Weill Cornell Medical College, part of the Graduate School of Medical Sciences. He has been a faculty member since 1987 and currently serves as Director of the Office of Medical Student Research. Education: B.A. in Natural Sciences (Genetics), University of Cambridge, 1977 M.A., University of Cambridge, 1980 Ph.D. in Molecular Biology, University of Edinburgh, 1982 Postdoctoral Fellow, University of California, San Francisco (with Harold Varmus) Postdoctoral Fellow, University of Strasbourg (with Pierre Chambon) Dr. Brown's research focuses on the Wnt family of signaling proteins and their roles in tissue development, homeostasis, and cancer. His work has significantly advanced the understanding of both canonical and non-canonical Wnt pathways, particularly in breast and colorectal cancers. He has shown that Wnt signaling contributes to oncogenesis through mechanisms involving stem-like cells, epithelial-to-mesenchymal transition, and crosstalk with other signaling cascades such as TGFβ. His research employs diverse models including cell culture, organoids, mouse models, and patient-derived tissues. His recent publications reveal a strong emphasis on Wnt signaling in cancer stem cells, metastasis, and signal transduction mechanisms. Trends include the role of Wnt in tumor microenvironments, regulation of ribosomal DNA, and therapeutic targeting of multiple pathways simultaneously. His work frequently appears in high-impact journals such as PNAS, Cancer Research, and Development. Scientific Awards: Royal Society European Science Exchange Fellowship Medical Research Council (U.K.) Travelling Fellowship Cornell Scholars Award Andrew W. Mellon Teacher-Scientist Award Pew Scholar in the Biomedical Sciences Irma T. Hirschl Career Scientist Award WCM Awards for Teaching Excellence WCM Awards for Excellence in Medical Education Dr. Brown has been actively involved in grant-funded research, including as a Co-Investigator on the Clinical and Translational Science Center (UL1) grant awarded by the National Center for Advancing Translational Sciences (2022–2027). He collaborates with a broad network of co-investigators across disciplines. He also mentors students and contributes to medical education, reflecting his dual commitment to research and teaching. His laboratory investigates Wnt signaling mechanisms and their implications for cancer therapeutics.

• Cancer Biology
• Wnt Signaling
• Stem Cells
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Claire Acevedo is an Assistant Professor in the Department of Mechanical and Aerospace Engineering at the University of California San Diego (UCSD), affiliated with the Jacobs School of Engineering. Her lab, the Fracture and Fatigue of Skeletal Tissues Laboratory (F² Lab), focuses on understanding mechanisms of deformation, fracture, and biological responses in skeletal tissues and biomaterials across molecular to macro scales. She holds a Ph.D. from the Swiss Federal Institute of Technology Lausanne (EPFL) and completed postdoctoral research at UC San Francisco and UC Berkeley/Lawrence Berkeley National Laboratory. Dr. Acevedo’s research is funded by the National Science Foundation (NSF), National Institutes of Health (NIH), and the Advanced Light Source. Her work bridges biomechanics, materials science, and high-energy X-ray physics to address bone fragility in aging and diabetes. Key projects include investigating collagen cross-linking effects on bone mechanics and developing novel imaging techniques like deep learning-enhanced synchrotron micro-CT. Education: Ph.D., Swiss Federal Institute of Technology Lausanne (EPFL) Postdoctoral Research: UC San Francisco & UC Berkeley/Lawrence Berkeley National Lab Previous Faculty Position: University of Utah (Mechanical Engineering) Recent contributions include the NSF CAREER Award for studying fracture mechanisms in fragile bones and an NIH R21 grant to explore collagen-level diabetes impacts. Her lab collaborates with the University of Utah Tanner Dance Program to develop K-12 educational initiatives linking dance with biomechanics. Publications span topics like synchrotron imaging innovations, diabetes-induced bone fragility, and collagen nanomechanics. Students in her lab have contributed to advancements in fatigue testing, cross-link analysis, and imaging algorithms. Awards: NSF CAREER Award (2024) NIH R21 Grant (2023) Alice L. Jee Award (2022) Nikon Small World Image of Distinction (2024) The F² Lab hosts a dynamic team with ongoing projects on glycemic effects, synchrotron techniques, and biomaterial design. Future work emphasizes translating findings into clinical fracture prevention strategies and educational outreach.

• Biomechanics
• Fracture Mechanics
• Skeletal Tissues
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Craig Morrell is a Professor at the University of Rochester School of Medicine and Dentistry , with joint appointments in the Departments of Medicine , Microbiology and Immunology , and Pathology and Laboratory Medicine . He serves as Associate Director of the Aab Cardiovascular Research Institute . Education: Sc.B. in Biology, Brown University (1995) D.V.M. , Tufts University School of Veterinary Medicine (2000) Ph.D. in Pathobiology, Johns Hopkins University (2005) His research examines the interface between platelets, vascular biology, and immune cells , focusing on platelet roles in thrombosis, inflammation, and immune regulation. Using advanced mouse models , his lab investigates platelet-derived mediators like β2M and PF4 in diseases such as malaria, stroke, and myocardial infarction. Article trends highlight platelets' dual roles in thrombosis and immune modulation , with recurring themes in vascular inflammation , ERK5 signaling , and age-related immune dysfunction . Scientific Awards: Kenneth M. Brinkous Young Investigators Prize (2008) Deans Gift research award (2006) Multiple travel scholarships and fellowships (2003-2005) Pathology Award-Excellence in Pathology (2000) Mentoring and Teaching : He has mentored 8 doctoral students , 7 undergraduates , and 6 postdoctoral fellows , with a focus on diversity. He serves on thesis committees and the URMC MSTP (MD/PhD) admissions committee . Labs and Collaborations : Leads the Morrell Lab at the Aab Cardiovascular Research Institute, collaborating with institutions like Johns Hopkins and Medical College of Wisconsin.

• Platelet Biology
• Vascular Inflammation
• Thrombosis
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Assistant Professor Low Jun Siong is affiliated with the Department of Microbiology and Immunology at the National University of Singapore (NUS), under the Yong Loo Lin School of Medicine. His research focuses on understanding T and B cell biology in the context of infection, cancer, and autoimmunity. He collaborates with clinical partners to characterize immune cell responses in patient cohorts and explores strategies to manipulate these cells for therapeutic purposes. Key areas of interest include antigen specificity, immune cell dysfunction, and immune-based disease interventions. Education: Holds a BSc and PhD (specific disciplines unspecified). Affiliated with the Cancer Science Institute (CSI) and A*STAR Infectious Diseases Labs. His work spans translational immunology, virology, and cancer immunotherapy. Recent projects include studies on SARS-CoV-2 immune responses, tumor microenvironment interactions, and tropical sponge microbiome evolution. He employs high-throughput approaches and machine learning for immune profiling. Research highlights include: Characterizing T/B cell responses against pathogens and cancers Engineering immune cells for enhanced functionality Investigating antibody mechanisms against coronaviruses Dissecting metabolic influences on T cell efficacy in tumors Exploring symbiotic microbiome evolution in marine environments No specific grants or advising roles are detailed in the provided text. He contributes to collaborative initiatives like the Department Safety and Health Programme (DSHP) and the Department Microbial Culture Collection (DMCC).

• Immunology
• Cancer Biology
• Infectious Diseases
• +۴ مورد دیگر

Dr. Alanna (Leni) Green is a Senior Research Fellow at the School of Medicine and Population Health, University of Sheffield. She leads the Cancer and Bone (CAB) Lab, focusing on eradicating chemotherapy-resistant dormant cancer cells in bone. Her academic journey includes a BBiomedSci at Monash University, a PhD at the University of Melbourne, and postdoctoral roles in the Sheffield Myeloma Research Team and Helleday’s lab. Education: BBiomedSci (Hons), Monash University PhD, University of Melbourne Her research explores bone-immune-cancer interactions, particularly how bone microenvironment cells protect tumors from therapy. Key areas include retinoic acid receptor signaling, vitamin A regulation of hematopoiesis, and novel drug development for myeloma and bone-metastatic cancers. Recent publications highlight her work in cancer metabolism (MTHFD2 inhibition), bone repair mechanisms, and microenvironmental regulation of lymphopoiesis. She has received over 20 awards, including Young Investigator Prizes from ECTS and ASBMR. Scientific Awards: Wellcome Trust Career Development Award (2024) Yorkshire Cancer Research Pioneer Advanced Fellowship (2024) Blood Cancer UK Project Grant (2023) Faculty MDH Early Career Researcher Prize (2020) Dr. Green supervises the Cancer and Bone Lab, which includes postdoctoral researchers and PhD students. She lectures on translational oncology and molecular medicine courses and actively contributes to professional societies like the Bone Research Society and ECTS.

• Bone-Immune-Cancer Interactions
• Cancer Dormancy
• Retinoic Acid Receptor Signaling
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Professor Franca Zanardi is a Full Professor of Organic Chemistry at the Department of Food and Pharmaceutical Sciences, University of Parma, Italy. With a career spanning over two decades, she transitioned from University Researcher (1998-2002) to Associate Professor (2002-2019) before achieving her current role in 2019. Her research focuses on biomedical applications of peptidomimetics, asymmetric synthesis methodologies, and radiolabeled agents for disease diagnosis. Research Interests: Design and synthesis of integrin-targeting peptidomimetics for tumor therapy and diagnostics Development of asymmetric organocatalytic strategies for molecular diversity Creation of radiolabeled compounds for non-invasive diagnosis of neoplastic diseases Scientific Awards: Adolfo Quilico Medal (2024) Premio alla Ricerca Scientifica 'Chimica Organica per le scienze della vita' (2017) Three Excellence Citation Awards (2012, 2012, 2016) Two Hot Paper Recognitions (2015, 2020) Grants and Leadership: Principal Investigator for SARS-CoV-2 biomedical projects (2020-2022), PRIN2020 grant recipient (2022-2024), and participant in multiple international research collaborations. She leads the BioOrganicSynthesiS (BOSS) Group and serves on editorial advisory boards including ACS Central Science .

• Small Molecules & Nanomaterials in Biomedicine
• Asymmetric Synthesis Methodologies
• Radiolabeled Agents for Early Diagnosis
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Dr. John F. Eberth is an Associate Professor at Drexel University's School of Biomedical Engineering, Science and Health Systems. As a cardiovascular engineer with expertise in mechanical controls, continuum biomechanics, and hydrogel-based extracellular matrix mimetics, he leads the Applied Biomechanics and Mechanobiology Lab (ABML) to investigate vascular behavior under mechanical stimuli. PhD in Biomedical Engineering from Texas A&M University (2008) MS in Mechanical Engineering from Clemson University (2004) BS in Mechanical Engineering from Clarkson University (2001) His research focuses on vascular pathology and mechanobiology, including: Aortopathy and aneurysm mechanics Endothelial dysfunction and arterial stiffening Hydrogel-based vascular grafts Calcification chelation therapy Coronary artery disease Perfusion tissue culture Recent publications demonstrate expertise in vascular imaging techniques, mechanical modeling, and therapeutic interventions. Key themes include drug-coated balloon development, collagen fiber mechanics, and bioreactor systems for vascular conditioning.

• Cardiovascular Engineering
• Biomechanics
• Mechanobiology
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Filipa Simões is a Group Leader and British Heart Foundation Intermediate Basic Science Research Fellow at the Institute of Developmental and Regenerative Medicine (IDRM), University of Oxford. She holds a Hugh Price Fellowship in Regenerative Medicine at Jesus College, Oxford. Her work focuses on immune cell programming in cardiac repair, leveraging genomics, spatial omics, and in vivo/in vitro models to dissect macrophage roles in heart regeneration. She completed her PhD at the University of Coimbra (Portugal) and postdoctoral research at Oxford, identifying epicardial subpopulations and macrophage contributions to cardiac scarring. Education: BSc Microbiology and Genetics, Faculty of Sciences, University of Lisbon PhD Biochemistry, University of Coimbra (research at Oxford’s Weatherall Institute) Postdoctoral Training: Department of Physiology, Anatomy, and Genetics, University of Oxford Research Interests: Filipa’s lab explores how macrophages are programmed by neighboring cells to repair heart attack damage. Key themes include immune-cell-cardiac crosstalk, fibrosis pathways, and regenerative signaling. Techniques employed span spatial genomics, functional assays, and zebrafish models to map cellular microenvironments. Awards: British Heart Foundation Intermediate Basic Science Research Fellowship British Heart Foundation Centre of Research Excellence Transition Fellowship Teaching: Leads undergraduate courses in Cardiovascular Development, Genomics, and Developmental Biology. Oversees postgraduate modules on cardio-immuno genomics and cardiac regeneration. Labs/Teams: Heads a multidisciplinary team at IDRM, integrating developmental biology, immunology, and regenerative medicine approaches to advance cardiac repair strategies.

• Regenerative Medicine
• Cardiovascular Biology
• Immunology
• +۳ مورد دیگر

Professor Alicia El Haj is the Interdisciplinary Professor of Cell Engineering at the School of Chemical Engineering and Director of the Institute of Translational Medicine at the University of Birmingham. She leads the Healthcare Technologies Institute (HTI), an interdisciplinary network advancing technologies for tissue healing and rehabilitation. Her research focuses on bioengineering and regenerative medicine, particularly in developing cell-based therapies using biomechanics, bioreactors, and imaging systems. She holds prestigious fellowships, including from the Royal Academy of Engineering and Royal Society of Biology, and has received awards such as the MRC Suffrage Award (2015). Director of the Institute of Translational Medicine Deputy Director of the MRC UKRMP Regen Med Hub Founder of MICA Biosystems, a spin-out company commercializing pharma screening tools Her work bridges biomedical science, engineering, and physical sciences to translate innovative therapies into clinical practice. Key interests include stem cell control systems, mechanotransduction via magnetic nanoparticles, and osteogenesis. Public engagement includes talks at the Royal Society and Hay Festival. Recent research trends emphasize nanomedicine applications, such as magnetic nanoparticle activation of cellular pathways, and interdisciplinary approaches to cartilage repair, bone regeneration, and organ-on-a-chip systems. Over 200 publications highlight her contributions to tissue engineering and regenerative medicine. Scientific Awards: Royal Society Merit Award (2014), MRC Suffrage Award (2015) Grants: EPSRC, MRC, BBSRC, ERC Advanced Grant Labs and affiliations include the HTI, EPSRC Centre for Innovative Manufacturing in Regenerative Medicine, and the European Council for TERMIS. Her work prioritizes bridging lab discoveries to clinical impact, with a focus on collaborative, interdisciplinary teams.

• Bioengineering
• Regenerative Medicine
• Cell Engineering
• +۷ مورد دیگر

Robert A. Sikes is an Associate Professor in the Department of Biological Sciences at the University of Delaware. His research focuses on mechanisms driving advanced prostate cancer progression, particularly the transition to castration-resistant states and metastasis to bone. He holds a B.A. from the University of Colorado, a Ph.D. from the University of Texas, and completed postdoctoral training at the University of Texas Health Science Center and M.D. Anderson Cancer Center. Education: B.A., University of Colorado Ph.D., University of Texas Postdoctoral Research, University of Texas Health Science Center Postdoctoral Research, M.D. Anderson Cancer Center His research investigates growth factor signaling (TGFβ/IGF1), bone marrow-stromal cell interactions, and molecular mediators of perineural migration in prostate cancer. Current projects include exploring Smad-independent Rho GTPase pathways in metastasis and adhesion molecule roles in cancer-bone microenvironment interactions. His lab is located in Wolf Hall.

• Prostate Cancer Metastasis
• Androgen Signaling in Cancer
• TGFβ and IGF1 Signaling Pathways
• +۳ مورد دیگر

John D. Imig, Ph.D., is a Professor and Chair of the Department of Pharmaceutical Sciences at the University of Arkansas for Medical Sciences (UAMS). He holds a B.A. in Biology from Blackburn College and a Ph.D. in Physiology & Biophysics from the University of Louisville. His research focuses on understanding how fatty acids influence cardiovascular, kidney, and metabolic functions. The Imig laboratory employs advanced techniques such as animal phenotyping, 3-D/organoid cell culturing, drug design, and omics approaches to develop therapies for cardiovascular, renal, and metabolic diseases. Dr. Imig is a Fellow of the American Heart Association and American Physiological Society, and holds memberships in prestigious organizations including the American Association for the Advancement of Science and the American Society of Nephrology. He has received notable awards such as the Arkansas Research Alliance Scholar (2022), Lewis K. Dahl Memorial Lecture (2019), and the American Heart Association Established Investigator (2004). His research emphasizes multi-target drug development for metabolic diseases, renal fibrosis mechanisms, and the role of epoxylipids in hypertension. Recent studies include investigations into chemotherapy-induced kidney and heart damage, dual enzyme inhibitors, and protective agents for organ transplantation. Collaborative efforts in drug design and omics-based approaches drive translational outcomes for clinical applications. Dr. Imig leads a lab renowned for integrative research spanning basic molecular mechanisms to preclinical drug testing. His work bridges academia and industry, addressing unmet clinical needs in cardiovascular and renal therapeutics. Ongoing projects explore novel therapies targeting epoxide pathways and nuclear receptors to combat chronic diseases.

• Cardiovascular Research
• Renal Physiology
• Metabolic Disorders
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David Weisblat is a Professor in the Department of Molecular and Cell Biology at UC Berkeley's College of Letters & Science. His research focuses on developmental and evolutionary processes in glossiphoniid leeches (e.g., Helobdella ), particularly their segmentation mechanisms and molecular phylogeny within Lophotrochozoa. He leads studies integrating embryological, genomic, and genetic approaches to understand how developmental pathways evolved across bilaterian animals. Research Interests: Weisblat’s work addresses how cell fates and signaling pathways (WNT, NOTCH, TGFβ) shape leech development, with emphasis on the evolutionary origins of segmentation. His lab combines microinjection techniques, transcriptome analysis, and CRISPR mutagenesis to explore stem cell dynamics and conserved developmental programs. Key Projects: Current efforts investigate grandparental stem cell divisions in segmentation and intercellular signaling during early embryogenesis. The lab’s genomic resources—including BAC libraries and EST databases—facilitate comparative studies across Lophotrochozoan taxa. Lab Contributions: The Weisblat lab pioneered Helobdella as a model organism, enabling breakthroughs in Evo-Devo. Their findings bridge developmental plasticity and evolutionary innovation, particularly in annelids versus arthropods/deuterostomes.

• Developmental Biology
• Evolutionary Developmental Biology (Evo-Devo)
• Molecular Phylogenetics
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Alex Banks is an Assistant Professor at Harvard Medical School and Beth Israel Deaconess Medical Center (BIDMC), with a focus on metabolic disorders. As Director of the Energy Balance core facility at BIDMC, he employs indirect calorimetry to study energy expenditure, food intake, and thermogenesis in mice. His research bridges genetic, pharmacological, and environmental factors to enhance understanding of obesity and metabolic diseases, while developing open-source tools like CalR to standardize metabolic analysis for the broader scientific community. Role: Assistant Professor Affiliation: Harvard Medical School, BIDMC Facility: Energy Balance Core Director Research Interests: The Banks Lab investigates mechanisms of obesity and metabolic disorders, emphasizing energy balance regulation through: Indirect calorimetry and metabolic rate analysis Genetic and pharmacological modulation of PPARγ Gut microbiome interactions with host metabolism Neural circuits controlling thermogenesis and food-seeking behavior Development of computational tools (CalR) for metabolic data Scientific Trends: Recent work spans obesity-linked phosphorylation of PPARγ, thermogenesis regulation via thyroid hormone, microbiome-dependent metabolic control, and novel methods for calorimetry. Collaborative projects address translational applications in bariatric surgery and metabolic drug development. Collaborations: The lab serves as a hub for Harvard/Boston-area researchers and provides freely accessible analytical tools to maximize utility of animal and human studies in combating obesity.

• Metabolic Disorders
• Energy Balance
• Obesity
• +۶ مورد دیگر